VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments.

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

1982 • 755 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1984 • 644 citations

The immunoglobulin heavy chain variable region (Igh‐V) locus in the mouse. I. One hundred Igh‐V genes comprise seven families of homologous genes

1984 • 537 citations

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

1981 • 497 citations

Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase

1986 • 452 citations

Regulation of Genome Rearrangement Events during Lymphocyte Differentiation

1986 • 422 citations

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.

1982 • 411 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 402 citations

Developmentally Controlled Expression of Immunoglobulin V _H Genes

1985 • 349 citations

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

1981 • 327 citations

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1982 • 278 citations

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

1984 • 261 citations

Genomic organization of the genes encoding mouse T-cell receptor α-chain

1985 • 202 citations

Pre-B cells in mouse bone marrow: immunofluorescence stathmokinetic studies of the proliferation of cytoplasmic mu-chain-bearing cells in normal mice.

1983 • 188 citations

Regulated progression of a cultured pre-B-cell line to the B-cell stage

1985 • 174 citations

Novel κ light-chain gene rearrangements in mouse λ light chain-producing B lymphocytes

1984 • 157 citations

Members of novel VH gene families are found in VDJ regions of polyclonally activated B-lymphocytes.

1985 • 147 citations

Myelogenous production and maturation of B lymphocytes in the mouse.

1981 • 126 citations

Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism.

1983 • 113 citations

Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type

1984 • 107 citations

Double recombination of a single immunoglobulin kappa-chain allele: implications for the mechanism of rearrangement.

1985 • 89 citations

The D-J_Hcomplex is an intermediate to the complete immunoglobulin beavy-chain V-region gene

1983 • 43 citations