Back to search

Mutations in β-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C 1 1Edited by J. Karn

Data up to Jan 2025

Published1999
Citations233
References71

Total Citations Per Year

Abstract

References (71)

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Current protocols in molecular biology

1988 • 7,584 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

1989 • 2,603 citations

Changes in the Cross-Striations of Muscle during Contraction and Stretch and their Structural Interpretation

1954 • 1,655 citations

Structural Changes in Muscle During Contraction: Interference Microscopy of Living Muscle Fibres

1954 • 1,532 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

[7] Preparation of myosin and its subfragments from rabbit skeletal muscle

1982 • 963 citations

Mutations in the Gene for Cardiac Myosin-Binding Protein C and Late-Onset Familial Hypertrophic Cardiomyopathy

1998 • 759 citations

A new protein of the thick filaments of vertebrate skeletal myofibrils

1973 • 615 citations

Mutations in the cardiac myosin binding protein–C gene on chromosome 11 cause familial hypertrophic cardiomyopathy

1995 • 574 citations

Cardiac myosin binding protein–C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy

1995 • 440 citations

Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?

1995 • 400 citations

Sensing the heat: the application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions

1996 • 341 citations

Towards a molecular understanding of titin.

1992 • 338 citations

Organization and Sequence of Human Cardiac Myosin Binding Protein C Gene (MYBPC3) and Identification of Mutations Predicted to Produce Truncated Proteins in Familial Hypertrophic Cardiomyopathy

1997 • 295 citations

The role of cytoskeletal proteins in cardiomyopathies

1998 • 275 citations

A Molecular Map of the Interactions between Titin and Myosin‐Binding Protein C

1996 • 272 citations

Molecular structure of the sarcomeric Z-disk: twotypes of titin interactions lead to an asymmetrical sorting of alpha -actinin

1998 • 248 citations

Conservation within the myosin motor domain: implications for structure and function

1996 • 221 citations

Structural interpretation of the mutations in the beta-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy.

1995 • 219 citations

The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif.

1993 • 203 citations

The muscle thin filament as a classical cooperative/allosteric regulatory system

1998 • 203 citations

Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts

1988 • 196 citations

Interaction of C-protein with myosin, myosin rod and light meromyosin

1975 • 196 citations

The ultrastructural location of C-protein, X-protein and H-protein in rabbit muscle

1986 • 188 citations

Alteration of myosin cross bridges by phosphorylation of myosin-binding protein C in cardiac muscle.

1996 • 183 citations

The binding of skeletal muscle C-protein to F-actin, and its relation to the interaction of actin with myosin subfragment-1

1978 • 178 citations

Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization Of cardiac transcript and protein.

1997 • 172 citations

The interaction of C-protein with heavy meromyosin and subfragment-2

1978 • 171 citations

The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers

1996 • 168 citations

Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin

1980 • 167 citations

Phosphorylation of purified cardiac muscle C-protein by purified cAMP-dependent and endogenous Ca2+-calmodulin-dependent protein kinases.

1984 • 155 citations

Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen.

1988 • 155 citations

Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: an intracellular member of the immunoglobulin superfamily.

1990 • 152 citations

A survey of interactions made by the giant protein titin

1993 • 141 citations

Wag the Tail: Structural Dynamics of Actomyosin

1998 • 140 citations

Sequential appearance of muscle‐specific proteins in myoblasts as a function of time after cell division: Evidence for a conserved myoblast differentiation program in skeletal muscle

1994 • 139 citations

The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy.

1997 • 138 citations

The carboxyl terminus of myosin binding protein C (MyBP-C, C-protein) specifies incorporation into the A-band of striated muscle

1996 • 131 citations

Mammalian skeletal muscle C-protein: purification from bovine muscle, binding to titin and the characterization of a full-length human cDNA

1992 • 130 citations

The C-proteins of rabbit red, white, and cardiac muscles.

1983 • 129 citations

Complete sequence of human fast‐type and slow‐type muscle myosin‐binding‐protein C (MyBP‐C)

1993 • 120 citations

Telomere length and proliferation potential of hematopoietic stem cells

1995 • 117 citations

Isoform Transitions of the Myosin Binding Protein C Family in Developing Human and Mouse Muscles

1998 • 111 citations

Phosphorylation of a myofibrillar protein of Mr 150 000 in perfused rat heart, and the tentative identification of this as C‐protein

1980 • 111 citations

Contractile protein mutations and heart disease

1996 • 109 citations

Effects of cholinergic and adrenergic agonists on phosphorylation of a 165,000-dalton myofibrillar protein in intact cardiac muscle.

1982 • 104 citations

[2] Preparation of myofibrils

1982 • 98 citations

Phosphorylation of chicken cardiac C-protein by calcium/calmodulin-dependent protein kinase II.

1991 • 90 citations

Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies.

1984 • 85 citations

C-Protein and the Periodicity in the Thick Filaments of Vertebrate Skeletal Muscle

1973 • 84 citations

Myosin minifilaments

1980 • 83 citations

Immunochemical analysis of C-protein isoform transitions during the development of chicken skeletal muscle

1984 • 72 citations

Complete primary structure of chicken cardiac C-protein (MyBP-C) and its expression in developing striated muscles

1995 • 71 citations

Molecular pathology of familial hypertrophic cardiomyopathy caused by mutations in the cardiac myosin binding protein C gene.

1998 • 62 citations

Isoform-specific Interaction of the Myosin-binding Proteins (MyBPs) with Skeletal and Cardiac Myosin Is a Property of the C-terminal Immunoglobulin Domain

1997 • 62 citations

Structure of C protein purified from cardiac muscle.

1985 • 60 citations

Contraction characteristics and ATPase activity of skeletal muscle fibers in the presence of antibody to myosin subfragment 2.

1992 • 51 citations

The leucine zippers of the HLH-LZ proteins Max and c-Myc preferentially form heterodimers

1995 • 51 citations

The Structure of the Head-Tail Junction of the Myosin Molecule

1996 • 49 citations

Heart C-protein is transiently expressed during skeletal muscle development in the embryo, but persists in cultured myogenic cells

1985 • 48 citations

The Coiled-Coil Helix in the Neck of Kinesin

1998 • 43 citations

Dynamic behaviour of the head-tail junction of myosin

1996 • 36 citations

Identification of a region susceptible to proteolysis in myosin subfragment-2.

1980 • 30 citations

The intracompartmental sorting of myosin alkali light chain isoproteins reflects the sequence of developmental expression as determined by double epitope-tagging competition

1996 • 29 citations

Influence of the cardiac myosin hinge region on contractile activity.

1991 • 27 citations

Assembly of Cardiac C-protein during Myofibrillogenesis in Myogenic Cells in Culture.

1995 • 14 citations

Myosin mutations in hypertrophic cardiomyopathy and functional implications.

1994 • 9 citations

Cited By (0)

Loading...