Isoform Transitions of the Myosin Binding Protein C Family in Developing Human and Mouse Muscles

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Molecular diversity of myofibrillar proteins: gene regulation and functional significance

1996 • 1,542 citations

A new protein of the thick filaments of vertebrate skeletal myofibrils

1973 • 615 citations

The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line.

1988 • 608 citations

Mutations in the cardiac myosin binding protein–C gene on chromosome 11 cause familial hypertrophic cardiomyopathy

1995 • 574 citations

Cardiac myosin binding protein–C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy

1995 • 440 citations

Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle

1994 • 437 citations

Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?

1995 • 400 citations

A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternate splicing.

1985 • 305 citations

Myogenesis in the mouse embryo: differential onset of expression of myogenic proteins and the involvement of titin in myofibril assembly.

1989 • 297 citations

Organization and Sequence of Human Cardiac Myosin Binding Protein C Gene (MYBPC3) and Identification of Mutations Predicted to Produce Truncated Proteins in Familial Hypertrophic Cardiomyopathy

1997 • 295 citations

A Molecular Map of the Interactions between Titin and Myosin‐Binding Protein C

1996 • 272 citations

The location of C-protein in rabbit skeletal muscle

1976 • 247 citations

Does titin regulate the length of muscle thick filaments?

1989 • 240 citations

Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene.

1993 • 223 citations

The structure of the sarcomeric M band: localization of defined domains of myomesin, M-protein, and the 250-kD carboxy-terminal region of titin by immunoelectron microscopy.

1996 • 212 citations

The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif.

1993 • 203 citations

The ultrastructural location of C-protein, X-protein and H-protein in rabbit muscle

1986 • 188 citations

Phosphorylation of purified cardiac muscle C-protein by purified cAMP-dependent and endogenous Ca2+-calmodulin-dependent protein kinases.

1984 • 155 citations

Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: an intracellular member of the immunoglobulin superfamily.

1990 • 152 citations

Cardiac troponin T in developing, regenerating and denervated rat skeletal muscle

1990 • 141 citations

Sequential appearance of muscle‐specific proteins in myoblasts as a function of time after cell division: Evidence for a conserved myoblast differentiation program in skeletal muscle

1994 • 139 citations

Mammalian skeletal muscle C-protein: purification from bovine muscle, binding to titin and the characterization of a full-length human cDNA

1992 • 130 citations

The C-proteins of rabbit red, white, and cardiac muscles.

1983 • 129 citations

Complete sequence of human fast‐type and slow‐type muscle myosin‐binding‐protein C (MyBP‐C)

1993 • 120 citations

Repetitive titin epitopes with a 42 nm spacing coincide in relative position with known a band striations also identified by major myosin-associated proteins an immunoelectron-microscoplcal study on myofibrils

1989 • 107 citations

Phosphorylation of chicken cardiac C-protein by calcium/calmodulin-dependent protein kinase II.

1991 • 90 citations

Mismatch between myosin heavy chain mRNA and protein distribution in human skeletal muscle fibers

1997 • 89 citations

Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies.

1984 • 85 citations

Molecular cloning of chicken myosin-binding protein (MyBP) H (86-kDa protein) reveals extensive homology with MyBP-C (C-protein) with conserved immunoglobulin C2 and fibronectin type III motifs.

1993 • 82 citations

Immunochemical analysis of C-protein isoform transitions during the development of chicken skeletal muscle

1984 • 72 citations

Complete primary structure of chicken cardiac C-protein (MyBP-C) and its expression in developing striated muscles

1995 • 71 citations

Identification of a program of contractile protein gene expression initiated upon skeletal muscle differentiation

1993 • 59 citations

Heart C-protein is transiently expressed during skeletal muscle development in the embryo, but persists in cultured myogenic cells

1985 • 48 citations

Assembly of the cardiac I-band region of titin/connectin: expression of the cardiac-specific regions and their structural relation to the elastic segments

1996 • 38 citations