Towards a molecular understanding of titin.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein

1988 • 1,501 citations

Enhancement by N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions

1986 • 865 citations

The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line.

1988 • 608 citations

Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

1989 • 368 citations

Myogenesis in the mouse embryo: differential onset of expression of myogenic proteins and the involvement of titin in myofibril assembly.

1989 • 297 citations

Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line.

1988 • 261 citations

The location of C-protein in rabbit skeletal muscle

1976 • 247 citations

A regular pattern of two types of 100-residue motif in the sequence of titin

1990 • 244 citations

Regulatory and structural motifs of chicken gizzard myosin light chain kinase.

1990 • 208 citations

Purification and properties of native titin

1984 • 203 citations

Evidence that nebulin is a protein‐ruler in muscle thin filaments

1991 • 196 citations

CAMs and Igs: Cell Adhesion and the Evolutionary Origins of Immunity

1987 • 187 citations

Use of DNA sequence and mutant analyses and antisense oligodeoxynucleotides to examine the molecular basis of nonmuscle myosin light chain kinase autoinhibition, calmodulin recognition, and activity.

1990 • 167 citations

[51] Gene isolation by screening λgt11 libraries with antibodies

1987 • 163 citations

Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: an intracellular member of the immunoglobulin superfamily.

1990 • 152 citations

Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA

1986 • 148 citations

Immunocytochemical studies of cardiac myofibrillogenesis in early chick embryos. I. Presence of immunofluorescent titin spots in premyofibril stages.

1987 • 131 citations

Molecular Size and Shape of β-Connectin, an Elastic Protein of Striated Muscle1

1984 • 130 citations

Identification and localization of high molecular weight proteins in insect flight and leg muscle.

1990 • 117 citations

Repetitive titin epitopes with a 42 nm spacing coincide in relative position with known a band striations also identified by major myosin-associated proteins an immunoelectron-microscoplcal study on myofibrils

1989 • 107 citations

Drosophila has a twitchin/titin-related gene that appears to encode projectin.

1991 • 103 citations

Amino acid sequence of rabbit skeletal muscle myosin light chain kinase

1986 • 96 citations

A myofibrillar protein of insect muscle related to vertebrate titin connects Z band and A band: purification and molecular characterization of invertebrate mini-titin

1990 • 95 citations

Giant polypeptides of skeletal muscle titin: Sedimentation equilibrium in guanidine hydrochloride

1988 • 86 citations

Biosynthesis of titin in cultured skeletal muscle cells.

1989 • 65 citations

Complete sequence and in vitro expression of a tissue-specific phosphatidylinositol-linked N-CAM isoform from skeletal muscle

1988 • 61 citations

Isolation of the cDNA encoding rat skeletal muscle myosin light chain kinase. Sequence and tissue distribution.

1988 • 56 citations

The early expression of myofibrillar proteins in round postmitotic myoblasts of embryonic skeletal muscle

1990 • 46 citations

Purification and physical properties of nematode mini-titins and their relation to twitchin

1991 • 42 citations

Molecular motors and the cytoskeleton

1991 • 21 citations

Direct amplification of cDNA inserts from λ libraries using the cloning-adapter as primer for PCR

1989 • 15 citations

Quantitative immunoenzymatic assay of human lutropin, with use of a bi-specific monoclonal antibody

1990 • 9 citations