Macrophages Can Decrease the Level of Cholesteryl Ester Hydroperoxides in Low Density Lipoprotein

Beyond Cholesterol

1989 • 6,533 citations

The role of lipid peroxidation and antioxidants in oxidative modification of LDL

1992 • 2,335 citations

Book ReviewAmbulatory Pediatric Care

1989 • 2,075 citations

The role of oxidized lipoproteins in atherogenesis

1996 • 1,382 citations

Role of vitamin E in preventing the oxidation of low-density lipoprotein

1991 • 649 citations

Role of oxidatively modified LDL in atherosclerosis

1990 • 614 citations

Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography

1987 • 362 citations

Human Atherosclerotic Plaque Contains Both Oxidized Lipids and Relatively Large Amounts of α-Tocopherol and Ascorbate

1995 • 357 citations

Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols

1995 • 315 citations

[50] Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence

1994 • 313 citations

α-tocopherol consumption during low-density-lipoprotein oxidation

1990 • 312 citations

Requirement for, Promotion, or Inhibition by α-Tocopherol of Radical-Induced Initiation of Plasma Lipoprotein Lipid Peroxidation

1997 • 264 citations

A Method for Defining the Stages of Low-Density Lipoprotein Oxidation by the Separation of Cholesterol and Cholesteryl Ester-Oxidation Products Using HPLC

1993 • 221 citations

Biothiols in Health and Disease

1995 • 199 citations

Lipid hydroperoxide involvement in copper-dependent and independent oxidation of low density lipoproteins.

1991 • 177 citations

Enzymatic reduction of phospholipid and cholesterol hydroperoxides in artificial bilayers and lipoproteins

1990 • 171 citations

Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions

1993 • 159 citations

Transport of cystine and cysteine and cell growth in cultured human diploid fibroblasts: Effect of glutamate and homocysteate

1982 • 130 citations

Lipids of human atheroma Part 4. Characterisation of a new group of polar sterol esters from human atherosclerotic plaques

1971 • 113 citations

Coexistence of Oxidized Lipids and α-Tocopherol in All Lipoprotein Density Fractions Isolated From Advanced Human Atherosclerotic Plaques

1999 • 106 citations

Reduction of HDL- and LDL-Associated Cholesterylester and Phospholipid Hydroperoxides by Phospholipid Hydroperoxide Glutathione Peroxidase and Ebselen (PZ-51)

1994 • 106 citations

Modified Low Density Lipoprotein Enhances the Secretion of Bile Salt-stimulated Cholesterol Esterase by Human Monocyte-Macrophages

1997 • 96 citations

Pro-oxidant effects of lipoxygenase-derived peroxides on the copper-initiated oxidation of low-density lipoprotein

1992 • 93 citations

Biological fate of amino acid, peptide and protein hydroperoxides

1995 • 88 citations

α‐Tocopherol does not inhibit hypochlorite‐induced oxidation of apolipoprotein B‐100 of low‐density lipoprotein

1997 • 78 citations

Greater selective uptake by Hep G2 cells of high-density lipoprotein cholesteryl ester hydroperoxides than of unoxidized cholesteryl esters

1993 • 78 citations

Thioredoxins: universal, yet specific thiol-disulfide redox cofactors.

1995 • 76 citations

Expression of hormone-sensitive lipase mRNA in macrophages.

1993 • 73 citations

Cholesterylester hydroperoxide reducing activity associated with isolated high- and low-density lipoproteins

1995 • 72 citations

Effects of ebselen and probucol on oxidative modifications of lipid and protein of low density lipoprotein induced by free radicals

1994 • 68 citations

Is α-tocopherol a reservoir for α-tocopheryl hydroquinone?

1995 • 64 citations

Degradation by cultured fibroblasts and macrophages of unmodified and 1,2-cyclohexanedione-modified low-density lipoprotein from normal and homozygous familial hypercholesterolaemic subjects

1982 • 58 citations

Formation of sulfhydryl groups in the culture medium by human diploid fibroblasts

1980 • 57 citations

Human macrophage-mediated oxidation of low-density lipoprotein is delayed and independent of superoxide production

1994 • 53 citations

Essential differences in cholesteryl ester metabolism between human monocyte-derived and J774 macrophages. Evidence against the presence of hormone-sensitive lipase in human macrophages.

1994 • 49 citations

Direct Copper Reduction by Macrophages

1997 • 49 citations

Phospholipid hydroperoxide cysteine peroxidase activity of human serum albumin

1999 • 48 citations

[33] Assessment of prooxidant activity of vitamin E in human low-density lipoprotein and plasma

1999 • 47 citations

Macrophages Require Both Iron and Copper to Oxidize Low-Density Lipoprotein in Hanks’ Balanced Salt Solution

1995 • 43 citations

Effects of supplementing with vitamin E on the uptake of low density lipoprotein and the stimulation of cholesteryl ester formation in macrophages

1994 • 41 citations

Batch-To-Batch Variation of Chelex-100 Confounds Metal-Catalysed Oxidation. Leaching of Inhibitory Compounds from A Batch of Chelex-100 and Their Removal by a Pre-Washing Procedure

1995 • 35 citations

Detection of Membrane Associated Thioredoxin on Human Cell Lines

1997 • 33 citations

α‐Tocopherol mediated peroxidation in the copper (II) and met myoglobininduced oxidation of human low density lipoprotein: The influence of lipid hydroperoxides

1995 • 33 citations

Abbau von Linols�urehydroperoxyden zu fl�chtigen Monocarbonylverbindungen

1976 • 31 citations

Cell-mediated oxidation of low-density lipoprotein: the elusive mechanism(s)

1996 • 27 citations

Prooxidant and Antioxidant Activities of Macrophages in Metal-Mediated LDL Oxidation

1999 • 20 citations

α-Tocopherol supplementation of macrophages does not influence their ability to oxidize LDL

1998 • 19 citations

Reduction of Lipid Hydroperoxides by Apolipoprotein B-100

1999 • 16 citations

Endothelial Cells Prevent Accumulation of Lipid Hydroperoxides in Low-Density Lipoprotein

1997 • 11 citations

α-Tocopherol enhances the peroxidase activity of hemoglobin on phospholipid hydroperoxide

1997 • 7 citations

Sulfhydryl groups generated by macrophages into the culture medium

1988 • 5 citations