Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

1973 • 7,616 citations

THIOREDOXIN

1985 • 1,885 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Reduction of Ribonucleotides

1979 • 1,170 citations

Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes.

1984 • 728 citations

Oxygen radical chemistry of polyunsaturated fatty acids

1989 • 716 citations

Selenocysteine: the 21st amino acid

1991 • 668 citations

On the Specificity of the Oxygenation of Unsaturated Fatty Acids Catalyzed by Soybean Lipoxidase

1967 • 660 citations

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1982 • 610 citations

Mammalian lipoxygenases: molecular structures and functions

1992 • 571 citations

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

1990 • 429 citations

The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase.

1994 • 361 citations

Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.

1979 • 324 citations

Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction.

1977 • 294 citations

Identification of a selenocysteyl-tRNASer in mammalian cells that recognizes the nonsense codon, UGA

1989 • 281 citations

Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non‐stoichiometric oxidation of NADPH in the presence of oxygen

1992 • 244 citations

Selenocysteine lyase, a novel enzyme that specifically acts on selenocysteine. Mammalian distribution and purification and properties of pig liver enzyme.

1982 • 233 citations

Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase.

1992 • 206 citations

Chemistry and Biochemistry of Flavoenzymes

2018 • 188 citations

Reactive oxygen-reducing and protein-refolding activities of adult t cell leukemia-derived factor /human thioredoxin

1992 • 176 citations

The level and half‐life of glutathione in human plasma

1980 • 165 citations

Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione

1993 • 162 citations

Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51)

1988 • 160 citations

Molecular biology of selenium with implications for its metabolism ¹

1991 • 143 citations

ADF, A Growth-Promoting Factor Derived from Adult T Cell Leukemia and Homologous to Thioredoxin: Involvement in Lymphocyte Immortalization by HTLV-I and EBV

1991 • 104 citations

Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase.

1980 • 88 citations

Arachidonate 15-lipoxygenase; characteristics and potential biological significance.

1991 • 72 citations

Selenocysteine

1987 • 37 citations

Rearrangement of 15-hydroperoxy-eicosatetraenoic acid (15-HPETE) during incubations with hemoglobin: A model for platelet lipoxygenase metabolism

1981 • 28 citations

Fatty acid hydroperoxide isomerase inSaprolegnia parasitica: Structural studies of epoxy alcohols formed from isomeric hydroperoxyoctadecadienoates

1989 • 27 citations

Glutathione peroxidase activity of D,L-selenocystine and selenocystamine

1980 • 26 citations

A gas-liquid chromatographic method for steric analysis of 2-hydroxy, 3-hydroxy, and 2,3-dihydroxy acids

1994 • 8 citations