Recruitment of Gcn5-containing Complexes during c-Myc-dependent Gene Activation

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability

2000 • 1,275 citations

[10] Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast

1983 • 1,095 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis

2000 • 994 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

1997 • 714 citations

The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins

1998 • 675 citations

Histone-like TAFs within the PCAF Histone Acetylase Complex

1998 • 534 citations

Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

1998 • 490 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

2000 • 479 citations

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

1992 • 458 citations

c-Myc Proteolysis by the Ubiquitin-Proteasome Pathway: Stabilization of c-Myc in Burkitt's Lymphoma Cells

2000 • 447 citations

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc

1999 • 427 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

1999 • 394 citations

Function of the c-Myc Oncogenic Transcription Factor

1999 • 379 citations

Expanded Lysine Acetylation Specificity of Gcn5 in Native Complexes

1999 • 371 citations

BIN1 is a novel MYC–interacting protein with features of a tumour suppressor

1996 • 358 citations

New light on Myc and Myb. Part I. Myc.

1990 • 325 citations

An ATPase/Helicase Complex Is an Essential Cofactor for Oncogenic Transformation by c-Myc

2000 • 314 citations

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

1994 • 313 citations

Deconstructing Myc: Figure 1.

2001 • 311 citations

c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover

2000 • 276 citations

The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region.

1992 • 266 citations

Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast.

1986 • 254 citations

Transcriptional elongation by RNA polymerase II is stimulated by transactivators

1994 • 243 citations

Binding and Suppression of the Myc Transcriptional Activation Domain by p107

1994 • 242 citations

DNA-bound Fos proteins activate transcription in yeast

1988 • 223 citations

Activator-dependent regulation of transcriptional pausing on nucleosomal templates.

1996 • 205 citations

c-Myc Mediates Activation of the cad Promoter via a Post-RNA Polymerase II Recruitment Mechanism

2001 • 199 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

Regulation of c-Myc through Phosphorylation at Ser-62 and Ser-71 by c-Jun N-Terminal Kinase

1999 • 185 citations

Hold back of RNA polymerase II at the transcription start site mediates down-regulation of c-myc in vivo.

1992 • 182 citations

Identification of TATA-binding Protein-free TAFII-containing Complex Subunits Suggests a Role in Nucleosome Acetylation and Signal Transduction

1999 • 181 citations

A Human SPT3-TAFII31-GCN5-L Acetylase Complex Distinct from Transcription Factor IID

1998 • 179 citations

New Myc-interacting proteins: a second Myc network emerges

1999 • 178 citations

Transcription factors vs nucleosomes: regulation of the PH05 promoter in yeast

1997 • 173 citations

The ADA Complex Is a Distinct Histone Acetyltransferase Complex in Saccharomyces cerevisiae

1999 • 172 citations

The TAFs in the HAT

1998 • 155 citations

Analysis of an Activator:Coactivator Complex Reveals an Essential Role for Secondary Structure in Transcriptional Activation

1998 • 155 citations

Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo

2000 • 149 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination

1998 • 142 citations

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.

1994 • 139 citations

Identification of a large Myc-binding protein that contains RCC1-like repeats

1998 • 136 citations

RNA Polymerase II Holoenzyme Recruitment Is Sufficient to Remodel Chromatin at the Yeast PHO5 Promoter

1997 • 133 citations

myc Boxes, Which Are Conserved in myc Family Proteins, Are Signals for Protein Degradation via the Proteasome

1998 • 130 citations

Recruitment of the SWI-SNF Chromatin Remodeling Complex as a Mechanism of Gene Activation by the Glucocorticoid Receptor τ1 Activation Domain

2000 • 127 citations

Structural and Functional Requirements for the Chromatin Transition at the PHO5 Promoter in Saccharomyces cerevisiae upon PHO5 Activation

1993 • 123 citations

Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes

2000 • 122 citations

The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter.

1994 • 121 citations

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

1998 • 120 citations

Hpr1 Is Preferentially Required for Transcription of Either Long or G+C-Rich DNA Sequences in Saccharomyces cerevisiae

2001 • 111 citations

MM-1, a Novel c-Myc-associating Protein That Represses Transcriptional Activity of c-Myc

1998 • 110 citations

Functional Interaction of the c-Myc Transactivation Domain with the TATA Binding Protein: Evidence for an Induced Fit Model of Transactivation Domain Folding

1996 • 109 citations

Two yeast acid phosphatase structural genes are the result of a tandem duplication and show different degrees of homology in their promoter and coding sequences.

1982 • 108 citations

The AD1 Transactivation Domain of E2A Contains a Highly Conserved Helix Which Is Required for Its Activity in both Saccharomyces cerevisiae and Mammalian Cells

1996 • 108 citations

DNA replication origin and transcriptional enhancer in c-myc gene share the c-myc protein binding sequences.

1989 • 106 citations

Continuous and widespread roles for the Swi-Snf complex in transcription

1999 • 106 citations

The N-Terminal Domain of c-Myc Associates with α-Tubulin and Microtubules In Vivo and In Vitro

1995 • 93 citations

DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc.

1989 • 87 citations

AMY‐1, a novel C‐MYC binding protein that stimulates transcription activity of C‐MYC

1998 • 85 citations

Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5

2001 • 81 citations

A new bind for Myc

1992 • 79 citations

How Transcriptional Activators Bind Target Proteins

2001 • 67 citations

Histone Acetyltransferase Complexes Can Mediate Transcriptional Activation by the Major Glucocorticoid Receptor Activation Domain

1999 • 63 citations

C-myc and the yeast transcription factor PHO4 share a common CACGTG-binding motif.

1991 • 59 citations

The structure and regulation of phosphoglucose isomerase in Saccharomyces cerevisiae

1988 • 43 citations

DNA-binding domain of human c-Myc produced in Escherichia coli.

1989 • 40 citations

Absence of a paused transcription complex from the c-myc P2 promoter of the translocation chromosome in Burkitt's lymphoma cells: implication for the c-myc P1/P2 promoter shift.

1993 • 36 citations

Overexpression of c-Myc and cell immortalization alters c-Myc phosphorylation

1997 • 35 citations

A new bind for Myc

1992 • 30 citations

Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity.

1993 • 29 citations

A protein-binding site in the c-myc promoter functions as a terminator of RNA polymerase II transcription.

1992 • 28 citations

c-Myc transactivation domain-associated kinases: Questionable role for map kinases in c-Myc phosphorylation

1999 • 26 citations

[8] In Vivo Analysis of nucleosome structure and transcription factor binding in Saccharomyces cerevisiae

1995 • 25 citations

RLR1 (THO2), required for expressing lacZ fusions in yeast, is conserved from yeast to humans and is a suppressor of SIN4

2000 • 20 citations

Transcription elongation of the murine ornithine decarboxylase (ODC) gene is regulated in vitro at two downstream elements by different attenuation mechanisms.

1995 • 9 citations

The transactivation potential of a c-Myc N-terminal region (residues 92- 143) is regulated by growth factor/Ras signaling

1996 • 8 citations

A Gal4-ς54 Hybrid Protein That Functions as a Potent Activator of RNA Polymerase II Transcription in Yeast

2001 • 6 citations

Deleted Work

1955 • 0 citations