Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

Basic local alignment search tool

1990 • 87,358 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Reduced surface: An efficient way to compute molecular surfaces

1996 • 1,864 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

Empirical correlation between protein backbone conformation and C.alpha. and C.beta. 13C nuclear magnetic resonance chemical shifts

1991 • 1,072 citations

PROMOTIF—A program to identify and analyze structural motifs in proteins

1996 • 1,046 citations

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1991 • 949 citations

Role of CBP/P300 in nuclear receptor signalling

1996 • 935 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

The application visualization system: a computational environment for scientific visualization

1989 • 865 citations

Efficient computation of three-dimensional protein structures in solution from nuclear magnetic resonance data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA

1991 • 787 citations

Amino‐aromatic interactions in proteins

1986 • 752 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

Methodological Advances in Protein NMR

1993 • 721 citations

Methodological advances in protein NMR

1993 • 686 citations

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

1992 • 684 citations

RNA Helicase A Mediates Association of CBP with RNA Polymerase II

1997 • 532 citations

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α

1996 • 492 citations

Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB

1992 • 458 citations

Two-dimensional NMR experiments for correlating carbon-13.beta. and proton.delta./.epsilon. chemical shifts of aromatic residues in 13C-labeled proteins via scalar couplings

1993 • 440 citations

Phosphorylation of CREB at Ser-133 Induces Complex Formation with CREB-Binding Protein via a Direct Mechanism

1996 • 396 citations

High-level expression of recombinant genes in Escherichia coli is dependent on the availability of the dnaY gene product

1989 • 363 citations

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

1995 • 361 citations

Heteronuclear filters in two-dimensional [¹H, ¹H]-NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

1990 • 354 citations

CBP as a transcriptional coactivator of c-Myb.

1996 • 347 citations

Measurement of HN-H? J couplings in calcium-free calmodulin using new 2D and 3D water-flip-back methods

1994 • 345 citations

Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP

1996 • 344 citations

Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints

1991 • 335 citations

The FSSP database of structurally aligned protein fold families.

1994 • 323 citations

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.

1995 • 318 citations

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo.

1992 • 295 citations

Amino/Aromatic Interactions in Proteins: Is the Evidence Stacked Against Hydrogen Bonding?

1994 • 294 citations

Induced α Helix in the VP16 Activation Domain upon Binding to a Human TAF

1997 • 286 citations

Planar Stacking Interactions of Arginine and Aromatic Side-Chains in Proteins

1994 • 283 citations

Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling

1997 • 283 citations

[11] Multidimensional heteronuclear nuclear magnetic resonance of proteins

1994 • 269 citations

Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors.

1997 • 236 citations

Transcriptional control: Versatile molecular glue

1996 • 231 citations

Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB.

1991 • 229 citations

Triple post‐transcriptional control

1990 • 217 citations

Adaptor-mediated Recruitment of RNA Polymerase II to a Signal-dependent Activator

1996 • 199 citations

The cAMP-regulated transcription factor CREB interactswith a component of the TFIID complex.

1994 • 192 citations

Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressers

1993 • 169 citations

A pulsed field gradient isotope‐filtered 3D ¹³C HMQC‐NOESY experiment for extracting intermolecular NOE contacts in molecular complexes

1994 • 161 citations

Measurement of three-bond nitrogen-carbon J couplings in proteins uniformly enriched in nitrogen-15 and carbon-13

1993 • 144 citations

A Structural Analysis of Phosphate and Sulphate Binding Sites in Proteins

1994 • 139 citations

Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP.

1996 • 120 citations

A positive genetic selection for disrupting protein–protein interactions: Identification of CREB mutations that prevent association with the coactivator CBP

1996 • 103 citations

Novel Pulse Sequences for the Resonance Assignment of Aromatic Side Chains in13C-Labeled Proteins

1996 • 22 citations