A Gal4-ς54 Hybrid Protein That Functions as a Potent Activator of RNA Polymerase II Transcription in Yeast

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1991 • 1,369 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The sigma 70 family: sequence conservation and evolutionary relationships

1992 • 894 citations

A new class of yeast transcriptional activators

1987 • 706 citations

Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery

1998 • 557 citations

Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.

1992 • 531 citations

Expression of sigma 54 (ntrA)-dependent genes is probably united by a common mechanism

1989 • 504 citations

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

1992 • 446 citations

Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter

1986 • 444 citations

Function of a Bacterial Activator Protein That Binds to Transcriptional Enhancers

1989 • 440 citations

Redundant roles for the TFIID and SAGA complexes in global transcription

2000 • 360 citations

Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction

1999 • 358 citations

The Functional and Regulatory Roles of Sigma Factors in Transcription

1998 • 357 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

1989 • 303 citations

SAP30, a Novel Protein Conserved between Human and Yeast, Is a Component of a Histone Deacetylase Complex

1998 • 288 citations

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

1997 • 277 citations

Cloning of a human gene encoding the general transcription initiation factor IIB

1991 • 274 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

1999 • 220 citations

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain

1995 • 188 citations

The ADA Complex Is a Distinct Histone Acetyltransferase Complex in Saccharomyces cerevisiae

1999 • 172 citations

Role of eukaryotic-type functional domains found in the prokaryotic enhancer receptor factor σ54

1990 • 171 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

Use of in vitro protein synthesis from polymerase chain reaction-generated templates to study interaction of Escherichia coli transcription factors with core RNA polymerase and for epitope mapping of monoclonal antibodies

1991 • 137 citations

Gene activation by recruitment of the RNA polymerase II holoenzyme.

1996 • 123 citations

Mechanisms of transcriptional activation in vivo: two steps forward

1996 • 122 citations

A yeast mating-selection scheme for detection of protein – protein interactions

1994 • 119 citations

Activator-Mediated Recruitment of the RNA Polymerase II Machinery Is the Predominant Mechanism for Transcriptional Activation in Yeast

1998 • 118 citations

Recruiting TATA-Binding Protein to a Promoter: Transcriptional Activation without an Upstream Activator

1995 • 108 citations

Related RNA Polymerase-binding Regions in Human RAP30/74 And Escherichia coli σ70

1991 • 99 citations

The Bacterial Enhancer-binding Protein NtrC as a Molecular Machine

1998 • 96 citations

Converting Escherichia coli RNA Polymerase into an Enhancer-Responsive Enzyme: Role of an NH ₂ -Terminal Leucine Patch in σ ⁵⁴

1995 • 93 citations

Promoter opening via a DNA fork junction binding activity

1998 • 90 citations

Amino-terminal sequences of sigma N (sigma 54) inhibit RNA polymerase isomerization

1999 • 73 citations

Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB

1997 • 73 citations

Core RNA Polymerase and Promoter DNA Interactions of Purified Domains of σN: Bipartite Functions

1995 • 66 citations

Functional Interaction between Ssu72 and the Rpb2 Subunit of RNA Polymerase II in Saccharomyces cerevisiae

2000 • 62 citations

A fork junction DNA-protein switch that controls promoter melting by the bacterial enhancer-dependent sigma factor

1999 • 54 citations

Sequences in σ N determining holoenzyme formation and properties 1 1Edited by J. Karn

1999 • 50 citations

An activation-specific role for transcription factor TFIIB in vivo

1999 • 44 citations

Specific Components of the SAGA Complex Are Required for Gcn4- and Gcr1-Mediated Activation of the his4-912δ Promoter in Saccharomyces cerevisiae

1999 • 38 citations

Identification of an N-Terminal Region of Sigma 54 Required for Enhancer Responsiveness

1998 • 38 citations

Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target

2000 • 36 citations

PCR mutagenesis identifies a polymerase-binding sequence of sigma 54 that includes a sigma 70 homology region

1995 • 34 citations

DNA-binding determinants of sigma 54 as deduced from libraries of mutations

1997 • 27 citations

Sigma Factor Relatives in Eukaryotes

1991 • 25 citations

Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum

2000 • 15 citations