ADP-ribosylation factors, 20,000 Mr guanine nucleotide-binding protein activators of cholera toxin and components of intracellular vesicular transport systems

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

1992 • 736 citations

Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development

1983 • 645 citations

G protein involvement in receptor-effector coupling.

1988 • 618 citations

ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein

1991 • 604 citations

The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.

1986 • 533 citations

'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles

1991 • 524 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.

1984 • 410 citations

Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor.

1977 • 391 citations

Binding of ARF and β-COP to Golgi Membranes: Possible Regulation by a Trimeric G Protein

1991 • 359 citations

Cholera

1973 • 294 citations

Protein N-myristoylation

1991 • 289 citations

Adp-Ribosylating Toxins and G Proteins: Insights into Signal Transduction

1990 • 285 citations

Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins

1991 • 267 citations

The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.

1992 • 259 citations

ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes.

1990 • 257 citations

Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition.

1979 • 230 citations

ADP-ribosylation factor is required for vesicular trafficking between the endoplasmic reticulum and the cis-Golgi compartment.

1992 • 213 citations

Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.

1991 • 207 citations

Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins

1991 • 199 citations

ADP-ribosylation of Gs promotes the dissociation of its alpha and beta subunits.

1984 • 196 citations

Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.

1992 • 185 citations

Chemical and immunological characterization of the 21-kDa ADP-ribosylation factor of adenylate cyclase.

1988 • 175 citations

Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase.

1982 • 172 citations

Nucleotide binding and cofactor activities of purified bovine brain and bacterially expressed ADP-ribosylation factor

1989 • 150 citations

Cholera toxin activation of adenylate cyclase. Roles of nucleoside triphosphates and a macromolecular factor in the ADP ribosylation of the GTP-dependent regulatory component.

1980 • 148 citations

Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain.

1988 • 141 citations

Two distinct members of the ADP-ribosylation factor family of GTP-binding proteins regulate cell-free intra-golgi transport

1992 • 128 citations

A role for ADP-ribosylation factor in nuclear vesicle dynamics

1992 • 110 citations

Effect of myristoylation on GTP-dependent binding of ADP-ribosylation factor to Golgi.

1993 • 106 citations

Guanine nucleotide-binding proteins in the intestinal parasite Giardia lamblia. Isolation of a gene encoding an approximately 20-kDa ADP-ribosylation factor.

1992 • 91 citations

Purification and characterization of type II heat-labile enterotoxin of Escherichia coli

1986 • 85 citations

Characterization of transducin from bovine retinal rod outer segments. Mechanism and effects of cholera toxin-catalyzed ADP-ribosylation.

1984 • 79 citations

Cloning of genes that encode a new heat-labile enterotoxin of Escherichia coli

1986 • 79 citations

Mechanisms of action of cholera and Escherichia coli enterotoxins

1979 • 76 citations

Production of type II heat-labile enterotoxin by Escherichia coli isolated from food and human feces

1986 • 70 citations

Advances in research on cholera and related diarrheas

1990 • 69 citations

Variation in chemical properties and antigenic determinants among type II heat-labile enterotoxins of Escherichia coli

1986 • 68 citations

Mechanism of cholera toxin activation by a guanine nucleotide-dependent 19 kDa protein

1990 • 62 citations

Mechanism of Activation of Cholera Toxin by ADP-Ribosylation Factor (ARF): Both Low- and High-Affinity Interactions of ARF with Guanine Nucleotides Promote Toxin Activation

1990 • 58 citations

Genetics of type IIa heat-labile enterotoxin of Escherichia coli: operon fusions, nucleotide sequence, and hybridization studies

1987 • 58 citations

NAD glycohydrolase and ADP-ribosyltransferase activities are intrinsic to the A1 peptide of choleragen.

1979 • 57 citations

Differential expression during development of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding protein activators of cholera toxin

1991 • 57 citations

GTP but not GDP analogues promote association of ADP-ribosylation factors, 20-kDa protein activators of cholera toxin, with phospholipids and PC-12 cell membranes.

1992 • 56 citations

Redistribution of ADP-ribosylation factor during stimulation of permeabilized cells with GTP analogues

1991 • 55 citations

ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl-terminal ADP-ribosylation factor domain.

1993 • 52 citations

Activation of Escherichia coli heat-labile enterotoxins by native and recombinant adenosine diphosphate-ribosylation factors, 20-kD guanine nucleotide-binding proteins.

1991 • 51 citations

A second guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin.

1983 • 51 citations

ADP-ribosylation by cholera toxin: functional analysis of a cellular system that stimulates the enzymic activity of cholera toxin fragment A1

1987 • 49 citations

Effects of temperature on ADP-ribosylation factor stimulation of cholera toxin activity

1993 • 48 citations

Interaction of ADP-ribosylation factor with Escherichia coli enterotoxin that contains an inactivating lysine 112 substitution.

1993 • 44 citations

Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.

1992 • 44 citations

Human and Giardia ADP-ribosylation factors (ARFs) complement ARF function in Saccharomyces cerevisiae.

1992 • 42 citations

Effects of phospholipid and GTP on recombinant ADP-ribosylation factors (ARFs). Molecular basis for differences in requirements for activity of mammalian ARFs.

1992 • 41 citations

ADP-ribosyltransferase activity of mono- and multi-(ADP-ribosylated) choleragen.

1980 • 39 citations

Isolation and characterization of the human gene for ADP-ribosylation factor 3, a 20-kDa guanine nucleotide-binding protein activator of cholera toxin.

1991 • 35 citations

Activation of pigeon erythrocyte adenylate cyclase by cholera toxin partial purification of an essential macromolecular factor from horse erythrocyte cytosol

1981 • 33 citations

Tissue and species distribution of mRNA encoding two ADP-ribosylation factors, 20-kDa guanine nucleotide binding proteins

1989 • 32 citations

Characterization of the gene for ADP-ribosylation factor (ARF) 2, a developmentally regulated, selectively expressed member of the ARF family of approximately 20-kDa guanine nucleotide-binding proteins.

1993 • 30 citations

Association of a 19- and a 21-kDa GTP-binding protein to pancreatic microsomal vesicles is regulated by the intravesicular pH established by a vacuolar-type H+-ATPase

1992 • 25 citations

Plasma membrane-associated component(s) that confer(s) cholera toxin sensitivity to adenylate cyclase

1982 • 25 citations

Regulation of ADP-ribosylation factor (ARF) expression. Cross-species conservation of the developmental and tissue-specific alternative polyadenylation of ARF 4 mRNA.

1992 • 24 citations

Cholera

1986 • 23 citations

Activation of immobilized, biotinylated choleragen A1 protein by a 19-kilodalton guanine nucleotide-binding protein

1989 • 19 citations

Molecular cloning, sequence analysis and mRNA expression of human ADP-ribosylation factor.

1989 • 18 citations

GTP‐induced fusion of isolated pancreatic microsomal vesicles is increased by acidification of the vesicle lumen

1990 • 16 citations

Microinjection of a 19-kDa Guanine Nucleotide-binding Protein Inhibits Maturation of Xenopus Oocytes

1989 • 15 citations

<b>PARTIAL PURIFICATION AND PROPERTIES OF A CYTOSOLIC PROTEIN FACTOR REQUIRED FOR THE ACTIVATION OF RAT LIVER ADENYLATE CYCLASE BY CHOLERA </b><b>TOXIN </b>

1982 • 14 citations

Corticosterone Regulates the Expression of ADP‐Ribosylation Factor Messenger RNA and Protein in Rat Cerebral Cortex

1990 • 13 citations