Characterization of transducin from bovine retinal rod outer segments. Mechanism and effects of cholera toxin-catalyzed ADP-ribosylation.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

The regulatory component of adenylate cyclase. Purification and properties.

1981 • 505 citations

Characterization of transducin from bovine retinal rod outer segments. I. Separation and reconstitution of the subunits.

1983 • 492 citations

Activation of Adenylate Cyclase by Choleragen

1979 • 394 citations

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.

1980 • 391 citations

Light-activated phosphodiesterase of the rod outer segment. Kinetics and parameters of activation and deactivation.

1978 • 353 citations

Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin.

1983 • 331 citations

The regulatory components of adenylate cyclase and transducin. A family of structurally homologous guanine nucleotide-binding proteins.

1983 • 304 citations

Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.

1978 • 281 citations

Complex formation between metarhodopsin II and GTP‐binding protein in bovine protoreceptor membranes leads to a shift of the photoproduct equilibrium

1982 • 259 citations

Lipid requirements for rhodopsin regenerability

1973 • 250 citations

Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin.

1982 • 221 citations

Amplitude, kinetics, and reversibility of a light-induced decrease in guanosine 3',5'-cyclic monophosphate in frog photoreceptor membranes.

1979 • 186 citations

Visual Transduction in Vertebrate Photoreceptors

1979 • 182 citations

Cholera toxin activation of adenylate cyclase. Roles of nucleoside triphosphates and a macromolecular factor in the ADP ribosylation of the GTP-dependent regulatory component.

1980 • 148 citations

Distribution of 3':5'-cyclic AMP and 3':5'-cyclic GMP in rabbit retina in vivo: selective effects of dark and light adaptation and ischemia.

1976 • 142 citations

Light-induced phosphorylation of rhodopsin in cattle photoreceptor membranes: substrate activation and inactivation

1977 • 120 citations

Protein configuration changes in the photolysis of rhodopsin II. The sequence of intermediates in thermal decay of cattle metarhodopsin in vitro

1966 • 110 citations

Chapter 14 Cyclic-Nucleotide Metabolism in Vertebrate Photoreceptors: A Remarkable Analogy and an Unraveling Enigma

1981 • 87 citations

Transducin: an amplifier protein in vision

1981 • 79 citations

Possible Involvement of Retinylidene Phospholipid in Photoisomerization of All-trans-Retinal to 11-cis-Retinal

1974 • 64 citations

Reactions of the Sulfhydryl Groups of Membrane-Bound Bovine Rhodopsin

1978 • 50 citations