ADP-ribosylation factor is required for vesicular trafficking between the endoplasmic reticulum and the cis-Golgi compartment.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

rab5 controls early endosome fusion in vitro

1991 • 1,090 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein

1991 • 604 citations

The ras protein family: evolutionary tree and role of conserved amino acids

1991 • 573 citations

The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.

1986 • 533 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin

1991 • 489 citations

Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae

1991 • 465 citations

A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus.

1989 • 443 citations

Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.

1984 • 410 citations

Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.

1991 • 391 citations

Purification and characterization of a rat liver Golgi alpha-mannosidase capable of processing asparagine-linked oligosaccharides.

1979 • 390 citations

The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

1989 • 387 citations

Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.

1990 • 384 citations

Small GTP-binding proteins in vesicular transport

1990 • 381 citations

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

1991 • 378 citations

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 • 376 citations

ADP-ribosylation factor is functionally and physically associated with the Golgi complex.

1990 • 372 citations

Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.

1989 • 351 citations

Multiple targets for brefeldin A

1991 • 347 citations

Semi-intact cells permeable to macromolecules: Use in reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex

1987 • 321 citations

Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic.

1989 • 314 citations

A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast.

1988 • 275 citations

Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins

1991 • 267 citations

The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.

1992 • 259 citations

ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes.

1990 • 257 citations

Selective inhibition of transcytosis by brefeldin A in MDCK cells

1991 • 254 citations

Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport

1989 • 250 citations

Systematic purification of five glycosidases from Streptococcus (Diplococcus) pneumoniae

1977 • 249 citations

Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.

1990 • 245 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants.

1989 • 234 citations

Molecular Cloning of YPT1/SEC4-Related cDNAs from an Epithelial Cell Line

1990 • 210 citations

Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins

1991 • 199 citations

Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.

1992 • 185 citations

Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus.

1991 • 183 citations

GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction.

1990 • 177 citations

Chemical and immunological characterization of the 21-kDa ADP-ribosylation factor of adenylate cyclase.

1988 • 175 citations

Small GTP-binding proteins and their role in transport

1991 • 164 citations

Mediation of the Attachment or Fusion Step in Vesicular Transport by the GTP-Binding Ypt1 Protein

1991 • 152 citations

Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER.

1991 • 143 citations

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

1987 • 142 citations

The ras-related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.

1989 • 136 citations

Synthetic peptides of the Rab effector domain inhibit vesicular transport through the secretory pathway.

1990 • 134 citations

Reconstitution of constitutive secretion using semi-intact cells: regulation by GTP but not calcium.

1991 • 113 citations

Requirement for GTP hydrolysis in the formation of secretory vesicles

1990 • 108 citations

Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity.

1991 • 91 citations

Transport of influenza HA from the trans-Golgi network to the apical surface of MDCK cells permeabilized in their basolateral plasma membranes: energy dependence and involvement of GTP-binding proteins.

1990 • 88 citations

Reconstitution of GTP-binding Sar1 protein function in ER to Golgi transport.

1991 • 84 citations

Activation of a Small GTP-Binding Protein by Nucleoside Diphosphate Kinase

1991 • 81 citations

Sequential intermediates in the transport of protein between the endoplasmic reticulum and the Golgi.

1990 • 69 citations

Sequential transport of protein between the endoplasmic reticulum and successive Golgi compartments in semi-intact cells

1991 • 67 citations

The GTP-binding Sar1 protein is localized to the early compartment of the yeast secretory pathway

1991 • 64 citations

Identification of a novel, N-ethylmaleimide-sensitive cytosolic factor required for vesicular transport from endosomes to the trans-Golgi network in vitro.

1991 • 56 citations

Intracellular membrane fusion

1991 • 55 citations