ADP-ribosylation of Gs promotes the dissociation of its alpha and beta subunits.

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.

1982 • 542 citations

The regulatory component of adenylate cyclase. Purification and properties.

1981 • 505 citations

Relationship between the beta-adrenergic receptor and adenylate cyclase.

1977 • 497 citations

Purification of the regulatory component of adenylate cyclase.

1980 • 497 citations

Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.

1984 • 410 citations

The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit.

1983 • 380 citations

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and the inhibition of adenylate cyclase in S49 lymphoma cyc- and wild type membranes.

1984 • 265 citations

The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution, activity, and properties of the 35,000-dalton (beta) subunit.

1983 • 237 citations

Reconstitution of catecholamine-stimulated guanosine triphosphatase activity

1983 • 213 citations

Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase.

1982 • 172 citations

ADVANCES IN PHARMACOLOGY AND THERAPEUTICS II

1982 • 58 citations

Effects of nucleoside triphosphates on choleragen-activated brain adenylate cyclase

1980 • 44 citations