Calretinin-immunoreactive neurons are resistant to β-amyloid toxicity in vitro

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Hydrogen peroxide mediates amyloid β protein toxicity

1994 • 2,065 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

1992 • 1,723 citations

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1992 • 1,602 citations

An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp ₇₁₇ ) Mutants

1994 • 1,463 citations

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid

1992 • 1,453 citations

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1993 • 1,422 citations

Calcium-binding proteins in the nervous system

1992 • 1,321 citations

Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

1991 • 1,191 citations

A mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease

1991 • 1,121 citations

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.

1994 • 1,085 citations

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.

1993 • 1,035 citations

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1989 • 987 citations

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

1992 • 982 citations

Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor

1993 • 909 citations

In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity

1991 • 833 citations

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β–amyloid precursor protein gene

1992 • 725 citations

β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1990 • 620 citations

Rapid Communication: Oxidative Stress Induces Apoptosis in Embryonic Cortical Neurons

1994 • 588 citations

Immunohistochemical evidence for apoptosis in Alzheimerʼs disease

1994 • 569 citations

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P.

1991 • 516 citations

Two classes of cortical GABA neurons defined by differential calcium binding protein immunoreactivities

1989 • 514 citations

A POST-MORTEM STUDY OF THE CHOLINERGIC AND GABA SYSTEMS IN SENILE DEMENTIA

1982 • 449 citations

Changes in Ca2+-binding proteins in human neurodegenerative disorders

1992 • 413 citations

Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF

1993 • 383 citations

Apoptosis mediated neurotoxicity induced by chronic application of β amyloid fragment 25–35

1993 • 343 citations

Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury

1987 • 334 citations

Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line.

1989 • 245 citations

Amyloid β peptide induces necrosis rather than apoptosis

1994 • 221 citations

Pro‐oxidants and mitochondrial Ca²⁺: their relationship to apoptosis and oncogenesis

1993 • 218 citations

Calretinin is present in non-pyramidal cells of the rat hippocampus—II. Co-existence with other calcium binding proteins and gaba

1992 • 215 citations

Rapid Communication: Ca²⁺ Channel Blockers Attenuate β‐Amyloid Peptide Toxicity to Cortical Neurons in Culture

1994 • 214 citations

Oxidative stress induced by glutamate receptor agonists

1993 • 210 citations

Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons

1994 • 208 citations

Two calcium-binding proteins mark many chick sensory neurons

1989 • 189 citations

Immunohistochemical markers in rat cortex: co-localization of calretinin and calbindin-D28k with neuropeptides and GABA

1992 • 174 citations

Calretinin-immunoreactive neocortical interneurons are unaffected in Alzheimer's disease

1993 • 171 citations

The relationship between excitotoxicity and oxidative stress in the central nervous system

1993 • 167 citations

Growth factors and vitamin E modify neuronal glutamate toxicity.

1992 • 167 citations

Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro

1994 • 152 citations

β-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease

1994 • 151 citations

Ultrastructural analysis of β-amyloid-induced apoptosis in cultured hippocampal neurons

1994 • 133 citations

GAMMA-AMINOBUTYRIC ACID CONCENTRATION IN BRAIN TISSUE AT TWO STAGES OF ALZHEIMER'S DISEASE

1988 • 130 citations

CORRELATION OF CORTICAL CHOLINERGIC AND GABA DEFICITS WITH QUANTITATIVE NEUROPATHOLOGICAL FINDINGS IN SENILE DEMENTIA

1984 • 129 citations

The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected β-amyloid in the rat brain

1992 • 127 citations

β-amyloid peptide in vitro toxicity: Lot-to-lot variability

1992 • 116 citations

A disorder of cortical GABAergic innervation in Alzheimer's disease

1987 • 113 citations

β-Amyloid neurotoxicity: A discussion of in vitro findings

1992 • 113 citations

B- Amyloid increases neuronal susceptibility to injufy by glucose deprivation

1991 • 111 citations

Calretinin immunoreactivity in the monkey hippocampal formation—I. Light and electron microscopic characteristics and co-localization with other calcium-binding proteins

1993 • 104 citations

Selective vulnerability of neurones in organic dementia

1977 • 99 citations

Ubiquinone Protects Cultured Neurons against Spontaneous and Excitotoxin-Induced Degeneration

1992 • 98 citations

Role of mitochondrial Ca2+ in the oxidative stress-induced dissipation of the mitochondrial membrane potential. Studies in isolated proximal tubular cells using the nephrotoxin 1,2-dichlorovinyl-L-cysteine.

1994 • 90 citations

Solvent effects on beta protein toxicity in vivo

1992 • 85 citations

Calretinin immunoreactivity in the monkey hippocampal formation—II. Intrinsic gabaergic and hypothalamic non-gabaergic systems: An experimental tracing and co-existence study

1993 • 85 citations

Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins

1990 • 80 citations

Cultured GABA-immunoreactive neurons are resistant to toxicity induced by β-amyloid

1993 • 80 citations

Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K

1994 • 78 citations

Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione

1991 • 75 citations

Intracerebral /sB-amyloid(25–35) produces tissue damage: Is it neurotoxic?

1992 • 74 citations

A subset of calretinin-positive neurons are abnormal in Alzheimer's disease

1994 • 64 citations

Loss of cortical GABA uptake sites in Alzheimer's disease

1988 • 46 citations

Biochemical changes in isolated hepatocytes exposed to tert-butyl hydroperoxide. implications for its cytotoxicity.

1991 • 40 citations