Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

2001 • 2,749 citations

Pharmacology of drugs that alter multidrug resistance in cancer.

1990 • 970 citations

Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance

2000 • 789 citations

The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment]

1996 • 739 citations

The Tyrosine Kinase Inhibitor CGP57148B Selectively Inhibits the Growth of BCR-ABL–Positive Cells

1997 • 646 citations

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

1993 • 517 citations

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR–ABL tyrosine kinase

2001 • 332 citations

Signal Transducer and Activator of Transcription (STAT)5 Activation by BCR/ABL Is Dependent on Intact Src Homology (SH)3 and SH2 Domains of BCR/ABL and Is Required for Leukemogenesis

1999 • 283 citations

Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells.

1986 • 255 citations

DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression.

1982 • 201 citations

Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study

2002 • 196 citations

ATP/Mg2+-dependent Cardiac Transport System for Glutathione S-Conjugates

1989 • 137 citations

Anti‐cancer drugs and glutathione stimulate vanadate‐induced trapping of nucleotide in multidrug resistance‐associated protein (MRP)

1997 • 118 citations

Signal transduction by wild-type and leukemogenic Abl proteins

1997 • 107 citations

BCR-ABL Delays Apoptosis Upstream of Procaspase-3 Activation

1998 • 100 citations

Effect of bisbenzylisoquinoline (biscoclaurine) alkaloids on multidrug resistance in KB human cancer cells.

1987 • 97 citations

Expression of the multidrug transporter, P‐glycoprotein, in chronic myelogenous leukaemia cells in blast crisis

1990 • 92 citations

Glutathione-dependent Binding of a Photoaffinity Analog of Agosterol A to the C-terminal Half of Human Multidrug Resistance Protein

2001 • 62 citations

Agosterol A, a novel polyhydroxylated sterol acetate reversing multidrug resistance from a marine sponge of Spongia sp.

1998 • 61 citations

Cepharanthine activates caspases and induces apoptosis in Jurkat and K562 human leukemia cell lines

2001 • 60 citations

Two pyridine analogues with more effective ability to reverse multidrug resistance and with lower calcium channel blocking activity than their dihydropyridine counterparts.

1990 • 49 citations

DNA-Mediated Transfer of Multiple Drug Resistance and Plasma Membrane Glycoprotein Expression

1982 • 48 citations

Increased sensitivity to vincristine of MDR cells by the leukotriene D4 receptor antagonist, ONO-1078

1998 • 32 citations

Functional expression of human P‐glycoprotein in Schizosaccharomyces pombe

1993 • 28 citations

Reversal of P-Glycoprotein and Multidrug-Resistance Protein-Mediated Drug Resistance in KB Cells by 5-O-Benzoylated Taxinine K

2000 • 26 citations

Anti-HIV-1 Activity and Structure-Activity Relationship of Cepharanoline Derivatives in Chronically Infected Cells

2001 • 23 citations

Synthetic isoprenoid photoaffinity labeling of P-glycoprotein specific to multidrug-resistant cells.

1989 • 22 citations

Overexpression of MDR-related p170 glycoprotein in chronic myeloid leukemia.

1994 • 17 citations

Why Some Leukemia Cells Resist STI-571

2001 • 12 citations

P170 Glycoprotein Expression and Impaired Anthracycline Retention in Chronic Myeloid Leukaemia

1995 • 11 citations