Anti‐cancer drugs and glutathione stimulate vanadate‐induced trapping of nucleotide in multidrug resistance‐associated protein (MRP)

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

1990 • 1,149 citations

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

1987 • 1,080 citations

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

1994 • 850 citations

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

1994 • 685 citations

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1994 • 621 citations

Multidrug Resistance Protein (MRP)-mediated Transport of Leukotriene C4 and Chemotherapeutic Agents in Membrane Vesicles

1996 • 555 citations

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

1995 • 501 citations

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

1994 • 435 citations

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

1995 • 362 citations

Inhibition of myosin ATPase by vanadate ion.

1979 • 269 citations

Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein.

1993 • 257 citations

Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active

1995 • 226 citations

Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein

1995 • 206 citations

Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies.

1994 • 196 citations

Reconstitution of drug-stimulated ATPase activity following co-expression of each half of human P-glycoprotein as separate polypeptides.

1994 • 174 citations

Inhibition of actomyosin ATPase by vanadate.

1982 • 121 citations

P-glycoprotein. ATP hydrolysis by the N-terminal nucleotide-binding domain.

1992 • 69 citations