MYCN-regulated microRNAs repress estrogen receptor-α ( ESR1 ) expression and neuronal differentiation in human neuroblastoma

MicroRNAs

2004 • 33,206 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Most mammalian mRNAs are conserved targets of microRNAs

2008 • 8,043 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

The impact of microRNAs on protein output

2008 • 3,546 citations

A microRNA polycistron as a potential human oncogene

2005 • 3,482 citations

c-Myc-regulated microRNAs modulate E2F1 expression

2005 • 2,371 citations

Neuroblastoma

2007 • 1,855 citations

Estrogen Carcinogenesis in Breast Cancer

2006 • 1,780 citations

Reflecting on 25 years with MYC

2008 • 1,447 citations

Widespread microRNA repression by Myc contributes to tumorigenesis

2007 • 1,300 citations

The c-Myc target gene network

2006 • 1,122 citations

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1997 • 830 citations

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

2007 • 800 citations

A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes

2006 • 715 citations

MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death

2008 • 706 citations

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation

2001 • 508 citations

A Genome-Wide Map of Conserved MicroRNA Targets in C. elegans

2006 • 414 citations

Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM

2008 • 379 citations

The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response

2009 • 323 citations

Inference of miRNA targets using evolutionary conservation and pathway analysis

2007 • 323 citations

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells

2001 • 319 citations

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

2008 • 315 citations

Mechanisms of microRNA deregulation in human cancer

2008 • 309 citations

Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.

1996 • 307 citations

Differential Patterns of MicroRNA Expression in Neuroblastoma Are Correlated with Prognosis, Differentiation, and Apoptosis

2008 • 297 citations

The MYCN oncogene is a direct target of miR-34a

2008 • 289 citations

Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

2006 • 283 citations

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

2008 • 274 citations

MYCN regulates oncogenic MicroRNAs in neuroblastoma

2007 • 258 citations

Estrogen-Receptor-Dependent Regulation of Neural Stem Cell Proliferation and Differentiation

2002 • 232 citations

Regulation of the Primate Fetal Adrenal Cortex*

1990 • 209 citations

Integrative Genomics Identifies Distinct Molecular Classes of Neuroblastoma and Shows That Multiple Genes Are Targeted by Regional Alterations in DNA Copy Number

2006 • 203 citations

The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells

2007 • 153 citations

A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage.

1996 • 152 citations

Prediction of mRNA polyadenylation sites by support vector machine

2006 • 125 citations

Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation

2006 • 107 citations

Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line.

1993 • 85 citations

Embryonal neural tumours and cell death

2009 • 64 citations

The Influence of Fetectomy at Midgestation upon the Serum Concentrations of Progesterone, Estrone, and Estradiol in Baboons

1980 • 57 citations

New miRNAs cloned from neuroblastoma

2008 • 50 citations

Mnt transcriptional repressor is functionally regulated during cell cycle progression

2005 • 34 citations

Principal neurons and small intensely fluorescent (SIF) cells in the rat superior cervical ganglion have distinct developmental histories

1991 • 30 citations

Increasing Fetal Adrenal Formation of Cortisol from Pregnenolone During Baboon (Papio papio) Gestation

1977 • 27 citations