A Genome-Wide Map of Conserved MicroRNA Targets in C. elegans

MicroRNAs

2004 • 33,206 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

MicroRNA expression profiles classify human cancers

2005 • 9,457 citations

<tt>BLAT</tt>—The <tt>BLAST</tt>-Like Alignment Tool

2002 • 8,153 citations

MicroRNAs: small RNAs with a big role in gene regulation

2004 • 6,733 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

TM4: A Free, Open-Source System for Microarray Data Management and Analysis

2003 • 4,724 citations

miRBase: microRNA sequences, targets and gene nomenclature

2005 • 4,598 citations

Combinatorial microRNA target predictions

2005 • 4,543 citations

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

2006 • 4,425 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

RAS Is Regulated by the let-7 MicroRNA Family

2005 • 3,637 citations

A microRNA polycistron as a potential human oncogene

2005 • 3,482 citations

MicroRNAs Modulate Hematopoietic Lineage Differentiation

2003 • 3,241 citations

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans

2001 • 3,225 citations

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

1991 • 3,108 citations

Gene finding in novel genomes

2004 • 2,806 citations

An Extensive Class of Small RNAs in Caenorhabditis elegans

2001 • 2,806 citations

c-Myc-regulated microRNAs modulate E2F1 expression

2005 • 2,371 citations

Principles of MicroRNA–Target Recognition

2005 • 2,335 citations

A pancreatic islet-specific microRNA regulates insulin secretion

2004 • 2,054 citations

bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

2003 • 2,012 citations

Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

2005 • 1,895 citations

The UCSC Genome Browser Database

2003 • 1,872 citations

A uniform system for microRNA annotation

2003 • 1,841 citations

Specificity of microRNA target selection in translational repression

2004 • 1,631 citations

Genome-wide RNAi screening in Caenorhabditis elegans

2003 • 1,474 citations

Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

2002 • 1,426 citations

MicroRNAs Regulate Brain Morphogenesis in Zebrafish

2005 • 1,287 citations

The microRNAs ofCaenorhabditis elegans

2003 • 1,232 citations

Animal MicroRNAs Confer Robustness to Gene Expression and Have a Significant Impact on 3′UTR Evolution

2005 • 1,079 citations

MicroRNA-143 Regulates Adipocyte Differentiation

2004 • 1,007 citations

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

2003 • 1,003 citations

The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics

2003 • 964 citations

The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA

1997 • 844 citations

Identification of Drosophila MicroRNA Targets

2003 • 792 citations

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor

2000 • 761 citations

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

2003 • 756 citations

MicroRNAs and Other Tiny Endogenous RNAs in C. elegans

2003 • 702 citations

Regulating Gene Expression through RNA Nuclear Retention

2005 • 675 citations

Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

2005 • 629 citations

The let-7 MicroRNA Family Members mir-48, mir-84, and mir-241 Function Together to Regulate Developmental Timing in Caenorhabditis elegans

2005 • 479 citations

Characterizing gene sets with FuncAssociate

2003 • 473 citations

Integrating genomic homology into gene structure prediction

2001 • 471 citations

microRNA Target Predictions across Seven Drosophila Species and Comparison to Mammalian Targets

2005 • 445 citations

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR

2004 • 441 citations

Crystal Structure of A. aeolicus Argonaute, a Site-Specific DNA-Guided Endoribonuclease, Provides Insights into RISC-Mediated mRNA Cleavage

2005 • 373 citations

The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 Controls Developmental Time and Is Regulated by MicroRNAs

2003 • 370 citations

Caenorhabditis phylogeny predicts convergence of hermaphroditism and extensive intron loss

2004 • 366 citations

Prediction of gene structure

1992 • 366 citations

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target

2003 • 354 citations

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode

2004 • 345 citations

Antisense-Mediated Depletion Reveals Essential and Specific Functions of MicroRNAs in Drosophila Development

2005 • 317 citations

Computational identification of microRNA targets

2004 • 308 citations

GeneMerge—post-genomic analysis, data mining, and hypothesis testing

2003 • 304 citations

Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs

2005 • 290 citations

MAVID: Constrained Ancestral Alignment of Multiple Sequences

2004 • 287 citations

Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis

2005 • 273 citations

The Temporal Patterning MicroRNA let-7 Regulates Several Transcription Factors at the Larval to Adult Transition in C. elegans

2005 • 260 citations

Incorporating structure to predict microRNA targets

2005 • 249 citations

A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.

1996 • 235 citations

Pioneer Axon Guidance by UNC-129, a C. elegans TGF-β

1998 • 229 citations

MicroRNA Mirn122a Reduces Expression of the Posttranscriptionally Regulated Germ Cell Transition Protein 2 (Tnp2) Messenger RNA (mRNA) by mRNA Cleavage1

2005 • 227 citations

WormBase: a comprehensive data resource for Caenorhabditis biology and genomics

2004 • 192 citations

The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter

2003 • 188 citations

A First Version of the Caenorhabditis elegans Promoterome

2004 • 177 citations

Architecture of a Validated MicroRNA::Target Interaction

2004 • 166 citations

The Timing oflin-4RNA Accumulation Controls the Timing of Postembryonic Developmental Events inCaenorhabditis elegans

1999 • 148 citations

Binding specificity and mRNA targets of a C. elegans PUF protein, FBF-1

2005 • 127 citations

A computational view of microRNAs and their targets

2005 • 113 citations

Prediction and verification of microRNA targets by MovingTargets, a highly adaptable prediction method

2005 • 88 citations

RETRACTED ARTICLE: Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal differentiation of NT2 cells

2003 • 83 citations

Revealing Posttranscriptional Regulatory Elements Through Network-Level Conservation

2005 • 79 citations

Developmental Timing in C. elegans Is Regulated by kin-20 and tim-1, Homologs of Core Circadian Clock Genes

2005 • 71 citations

RNAiDB and PhenoBlast: web tools for genome-wide phenotypic mapping projects

2003 • 70 citations

Detection of MicroRNAs and Assays to Monitor MicroRNA Activities In Vivo and In Vitro

2005 • 23 citations

Expression patterns of predicted genes from the C. elegans genome sequence visualized by FISH in whole organisms

1995 • 23 citations