Antioxidant Function of the Mitochondrial Protein SP-22 in the Cardiovascular System

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Genomic sequencing.

1984 • 8,343 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

1995 • 3,305 citations

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

Oxidative damage and mitochondrial decay in aging.

1994 • 2,024 citations

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

1997 • 1,762 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

OXIDATION OF FREE AMINO ACIDS AND AMINO ACID RESIDUES IN PROTEINS BY RADIOLYSIS AND BY METAL-CATALYZED REACTIONS

1993 • 1,377 citations

Myocardial reperfusion: a double-edged sword?

1985 • 1,355 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

The Reduction of Cytochrome c by Milk Xanthine Oxidase

1968 • 1,201 citations

Thioredoxin-dependent peroxide reductase from yeast.

1994 • 940 citations

Induction of Manganous Superoxide Dismutase by Tumor Necrosis Factor: Possible Protective Mechanism

1988 • 933 citations

Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.

1984 • 915 citations

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Gene inhibition using antisense oligodeoxynucleotides

1994 • 746 citations

Superoxide and peroxynitrite inatherosclerosis.

1994 • 674 citations

Mammalian Peroxiredoxin Isoforms Can Reduce Hydrogen Peroxide Generated in Response to Growth Factors and Tumor Necrosis Factor-α

1998 • 672 citations

Superoxide radicals as precursors of mitochondrial hydrogen peroxide

1974 • 627 citations

Detection of catalase in rat heart mitochondria.

1991 • 556 citations

Characterization of a Mammalian Peroxiredoxin That Contains One Conserved Cysteine

1998 • 439 citations

Differential regulation of antioxidant enzymes in response to oxidants.

1991 • 411 citations

Transition series metals and sulfhydryl reagents induce the synthesis of four proteins in eukaryotic cells

1980 • 343 citations

Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes.

1993 • 334 citations

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

1990 • 323 citations

Free radicals and myocardial injury: pharmacologic implications.

1986 • 294 citations

NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH–ubiquinone reductase preparation

1979 • 293 citations

Vitamin C Improves Endothelial Dysfunction of Epicardial Coronary Arteries in Hypertensive Patients

1997 • 288 citations

Role of superoxide in deoxyribonucleic acid strand scission

1980 • 276 citations

The independent effects of oxygen radical scavengers on canine infarct size. Reduction by superoxide dismutase but not catalase.

1985 • 234 citations

Thioredoxin regenerates proteins inactivated by oxidative stress in endothelial cells

1992 • 210 citations

Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein.

1993 • 192 citations

Intracellular Localization of 8-Oxo-dGTPase in Human Cells, with Special Reference to the Role of the Enzyme in Mitochondria

1995 • 191 citations

The Thiol-specific Antioxidant Enzyme Prevents Mitochondrial Permeability Transition

1998 • 174 citations

Alkyl hydroperoxide reductase from Salmonella typhimurium. Sequence and homology to thioredoxin reductase and other flavoprotein disulfide oxidoreductases.

1990 • 173 citations

Evaluation of the role of xanthine oxidase in myocardial reperfusion injury.

1990 • 169 citations

Long-Term Preservation of Ischemic Myocardium after Experimental Coronary Artery Occlusion

1978 • 167 citations

SP‐22 is a Thioredoxin‐Dependent Peroxide Reductase in Mitochondria

1997 • 159 citations

Induction of an antioxidant protein of Saccharomyces cerevisiae by O2, Fe3+, or 2-mercaptoethanol.

1989 • 134 citations

Identification of a Natural Killer Enhancing Factor (NKEF) from Human Erythroid Cells

1993 • 128 citations

Increased Oxidative Damage to Mitochondrial DNA Following Chronic Ethanol Consumption

1997 • 124 citations

Cloning of a housekeeping-type gene (MERS) preferentially expressed in murine erythroleukemia cells

1989 • 110 citations

Purification and Characterization of a Substrate Protein for Mitochondrial ATP-Dependent Protease in Bovine Adrenal Cortex

1994 • 100 citations

Induction of the antioxidant stress proteins heme oxygenase‐1 and MSP23 by stress agents and oxidised LDL in cultured vascular smooth muscle cells

1995 • 99 citations

Metabolic Disturbances During Myocardial Ischemia and Reperfusion

1995 • 67 citations

Possible Function of SP-22, a Substrate of Mitochondrial ATP-Dependent Protease, as a Radical Scavenger

1995 • 61 citations

Differential induction of constitutive and inducible nitric oxide synthases by distinct inflammatory stimuli in bovine aortic endothelial cells

1997 • 41 citations

Endogenous intracellular glutathionyl radicals are generated in neuroblastoma cells under hydrogen peroxide oxidative stress.

1995 • 39 citations

Induction of a 23 kDa stress protein by oxidative and sulfhydryl-reactive agents in mouse peritoneal macrophages

1993 • 35 citations

Subcellular Localization of Glutathione and Thermal Sensitivity

1988 • 21 citations