Superoxide and peroxynitrite inatherosclerosis.

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Superoxide Dismutase

1969 • 12,578 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

1986 • 2,416 citations

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

1991 • 2,215 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

Peroxynitrite formation from macrophage-derived nitric oxide

1992 • 1,118 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide

1992 • 702 citations

Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5'-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta.

1987 • 534 citations

Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta.

1990 • 527 citations

Copper,zinc superoxide dismutase is primarily a cytosolic protein in human cells.

1992 • 492 citations

The Simultaneous Generation of Superoxide and Nitric Oxide Can Initiate Lipid Peroxidation in Human Low Density Lipoprotein

1992 • 460 citations

Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries.

1988 • 422 citations

Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits.

1991 • 403 citations

Enzymatic methods for quantification of lipoprotein lipids

1986 • 395 citations

Oxygen-derived free radicals, endothelium, and responsiveness of vascular smooth muscle

1986 • 380 citations

Peroxynitrite-induced luminol chemiluminescence

1993 • 371 citations

Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis.

1987 • 354 citations

Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta.

1991 • 340 citations

Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity

1991 • 322 citations

Loss of selective endothelial cell vasoactive functions caused by hypercholesterolemia in pig coronary arteries.

1988 • 265 citations

Vascular effects of oxygen-derived free radicals

1988 • 242 citations

Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.

1977 • 238 citations

Role of superoxide in endothelial-cell modification of low-density lipoproteins

1988 • 228 citations

Hypertriglyceridemic Very Low Density Lipoproteins Induce Triglyceride Synthesis and Accumulation in Mouse Peritoneal Macrophages

1982 • 195 citations

Native and oxidized low‐density lipoproteins have different inhibitory effects on endothelium‐derived relaxing factor in the rabbit aorta

1990 • 183 citations

Endothelium-dependent relaxation in experimental atherosclerosis in the rabbit.

1987 • 182 citations

Aortic antioxidant defence mechanisms: time-related changes in cholesterol-fed rabbits

1990 • 123 citations

Vascular bound recombinant extracellular superoxide dismutase type C protects against the detrimental effects of superoxide radicals on endothelium-dependent arterial relaxation.

1992 • 112 citations

L-arginine evokes both endothelium-dependent and -independent relaxations in L-arginine-depleted aortas of the rat.

1991 • 110 citations

Free radical modification of lipoproteins and cholesterol accumulation in cells upon atherosclerosis

1991 • 93 citations

Effect of lipid feeding on endothelium dependent relaxation in rabbit aortic preparations

1987 • 87 citations

Putative mechanisms of the impairment of endothelium-dependent relaxation of the aorta with atheromatous plaque in heritable hyperlipidemic rabbits.

1991 • 84 citations

The Pulmonary Circulation, Normal and Abnormal

1990 • 71 citations

Immunolocalization of native antioxidant scavenger enzymes in early hypertensive and atherosclerotic arteries. Role of oxygen free radicals.

1992 • 70 citations

Endothelium-dependent relaxation to aggregating platelets in isolated basilar arteries of control and hypercholesterolemic pigs.

1988 • 68 citations

Vascular responses to leukocyte products in atherosclerotic primates.

1989 • 55 citations

<i>L</i>-Arginine Does Not Restore Endothelial Dysfunction in Atherosclerotic Rabbit Aorta in vitro

1991 • 50 citations

Mechanism of Thrombin-Induced Endothelium-Dependent Coronary Vasodilation in Dogs: Role of its Proteolytic Enzymatic Activity

1986 • 39 citations

[8] pH-Sensitive immunoliposomes

1987 • 26 citations

Inhibition of endothelium-dependent relaxation by oxidized low-density lipoproteins

1990 • 17 citations