Metabolic Disturbances During Myocardial Ischemia and Reperfusion

CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION

1966 • 3,631 citations

The stunned myocardium: prolonged, postischemic ventricular dysfunction.

1982 • 2,825 citations

The hibernating myocardium

1989 • 1,256 citations

Mechanism of myocardial "stunning".

1990 • 995 citations

A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina.

1985 • 589 citations

Myocardial 'stunning' in man.

1992 • 531 citations

Clinical outcome of patients with advanced coronary artery disease after viability studies with positron emission tomography

1992 • 528 citations

Reperfusion injury and its pharmacologic modification.

1989 • 509 citations

Myocardial contractile function during ischemia and hypoxia.

1987 • 486 citations

Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation.

1991 • 423 citations

Oxygen-mediated myocardial damage during ischameia and reperfusion: Role of the cellular defences against oxygen toxicity

1985 • 384 citations

Studies of experimental coronary artery reperfusion. Effects on infarct size, myocardial function, biochemistry, ultrastructure and microvascular damage.

1983 • 363 citations

Occurrence of oxidative stress during reperfusion of the human heart.

1990 • 297 citations

Kinetic evidence for a heart mitochondrial pore activated by Ca²⁺, inorganic phosphate and oxidative stress

1988 • 293 citations

Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol.

1984 • 265 citations

Recruitment of an inotropic reserve in moderately ischemic myocardium at the expense of metabolic recovery. A model of short-term hibernation.

1992 • 251 citations

The time of onset and severity of acidosis in myocardial ischaemia

1980 • 249 citations

Oxygen free radicals and myocardial damage: Protective role of thiol-containing agents

1991 • 240 citations

Excitation-contraction coupling in postischemic myocardium. Does failure of activator Ca2+ transients underlie stunning?

1990 • 204 citations

Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury.

1989 • 140 citations

Ischemia, reperfusion, and the determinants of tissue injury

1990 • 123 citations

Myocardial damage during ischaemia and reperfusion

1993 • 115 citations

Calcium antagonists and cardiovascular disease

1984 • 113 citations

Reactive oxygen species modify the structure and function of the cardiac sarcoplasmic reticulum calcium-release channel.

1991 • 101 citations

Nifedipine administered after reperfusion ablates systolic contractile dysfunction of postischemic “stunned” myocardium

1989 • 98 citations

A protective effect of a mild acidosis on hypoxic heart muscle

1979 • 89 citations

Annual of Cardiac Surgery

1995 • 88 citations

Improved Recovery of Myocardial Segment Function Following a Short Coronary Occlusion in Dogs by Nicorandil, a Potential New Antianginal Agent, and Nifedipine

1985 • 88 citations

Mitochondrial energy production and cation control in myocardial ischaemia and reperfusion

1993 • 64 citations

The occurrence of oxidative stress during reperfusion in experimental animals and men

1991 • 54 citations

Metabolic changes during post-ischaemic reperfusion

1988 • 53 citations

Myocardial stunning: a role for calcium antagonists during reperfusion?

1992 • 44 citations

Superoxide dismutase: Possible therapeutic use in cardiovascular disease

1989 • 29 citations

Stunned and Hibernating Myocardium

1992 • 27 citations

Stunning: Damaging or protective to the myocardium?

1991 • 19 citations

The role of free radicals in ischaemic myocardium

1990 • 18 citations

Myocardial metabolism during intracoronary thrombolysis. Two illustrative cases

1987 • 8 citations

Effects of the novel calcium channel blocker, anipamil, on the isolated rabbit heart

1992 • 5 citations