Type I interferons (IFN-α and -β) suppress cytotoxin (tumor necrosis factor-α and lymphotoxin) production by mitogen-stimulated human peripheral blood mononuclear cells

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

1986 • 1,282 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

Correlations and interactions in the production of interleukin-6 (IL- 6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF

1990 • 991 citations

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1988 • 739 citations

Effect of interleukin 2, interferon-gamma, and mitogens on the production of tumor necrosis factors alpha and beta.

1985 • 492 citations

RAISED SERUM LEVELS OF TUMOUR NECROSIS FACTOR IN PARASITIC INFECTIONS

1986 • 469 citations

Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes.

1987 • 372 citations

Close link between reduction of c-myc expression by interferon and G0/G1 arrest

1985 • 358 citations

Effect of gamma interferon on cachectin expression by mononuclear phagocytes. Reversal of the lpsd (endotoxin resistance) phenotype.

1986 • 241 citations

Glucocorticoids suppress the production of tumour necrosis factor by lipopolysaccharide-stimulated human monocytes.

1988 • 221 citations

Tumor Necrosis Factors: Gene Structure and Biological Activities

1986 • 215 citations

Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells.

1985 • 203 citations

Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody.

1988 • 187 citations

The Common Mediator of Shock, Cachexia, and Tumor Necrosis

1988 • 175 citations

Production of tumor necrosis factor/cachectin by human B cell lines and tonsillar B cells.

1988 • 173 citations

Cachectin (Tumor Necrosis Factor)

1988 • 170 citations

Human Alpha- and Beta-Interferon But Not Gamma- Suppress theIn VitroReplication of LAV, HTLV-III, and ARV-2

1986 • 147 citations

Dynamics of dibutyryl cyclic AMP- and prostaglandin E2-mediated suppression of lipopolysaccharide-induced tumor necrosis factor alpha gene expression

1989 • 126 citations

125I-labelled Human Interferons Alpha, Beta and Gamma: Comparative Receptor-binding Data

1985 • 123 citations

Cytocidal effect of tumor necrosis factor on cells chronically infected with human immunodeficiency virus (HIV): enhancement of HIV replication

1989 • 120 citations

Mechanisms that regulate the production and effects of tumor necrosis factor-alpha.

1989 • 115 citations

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

1988 • 83 citations

Interferon-gamma overcomes glucocorticoid suppression of cachectin/tumor necrosis factor biosynthesis by murine macrophages.

1990 • 73 citations

Interferon-gamma enhances induction of lymphotoxin in recombinant interleukin 2-stimulated peripheral blood mononuclear cells.

1985 • 56 citations

Cytokines in Cancer Therapy

1994 • 54 citations

Role of Interferon-γ in Counteracting the Suppressive Effects of Transforming Growth Factor-β2 and Glucocorticoids on the Production of Tumor Necrosis Factor-α

1990 • 44 citations

Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis

1988 • 43 citations

Interferon-lnduced resistance to the killing by NK cells: A preferential effect of IFN-γ

1983 • 36 citations

T Cell‐Mediated Production of Tumour Necrosis Factor‐α by Monocytes

1988 • 31 citations

Comparison of patterns of expression of tumour necrosis factor, lymphotoxin and interleukin-6 MRNA

1988 • 27 citations

Human interferons: structure and function.

1987 • 27 citations

Clinical applications of tumour necrosis factor

1989 • 21 citations

The Effects of Various Cytokines on Interleukin-6 and Interferon-α Synthesis in Human Peripheral Blood Mononuclear Cells

1990 • 9 citations

Antiproliferative and Clinical Antitumor Effects of Interferons

1988 • 4 citations