β1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1997 • 5,665 citations

Integrin Signaling

1999 • 3,705 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

1997 • 3,130 citations

Regulation of Cell Death Protease Caspase-9 by Phosphorylation

1998 • 3,129 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

1997 • 2,442 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

1995 • 1,968 citations

The extracellular matrix as a cell survival factor.

1993 • 1,541 citations

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1999 • 1,540 citations

Ca ²⁺ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD

1999 • 1,136 citations

Control of adhesion-dependent cell survival by focal adhesion kinase.

1996 • 1,113 citations

Anchorage dependence, integrins, and apoptosis

1994 • 1,016 citations

The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.

1990 • 629 citations

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression.

1995 • 627 citations

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis.

1996 • 371 citations

Distinct Functions of α3 and αV Integrin Receptors in Neuronal Migration and Laminar Organization of the Cerebral Cortex

1999 • 344 citations

Cleavage of Focal Adhesion Kinase by Caspases during Apoptosis

1997 • 338 citations

An antibody to a receptor for fibronectin and laminin perturbs cranial neural crest development in vivo

1986 • 304 citations

Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensin

1993 • 253 citations

Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis

1999 • 209 citations

Caspases Cleave Focal Adhesion Kinase during Apoptosis to Generate a FRNK-like Polypeptide

1998 • 193 citations

Signal transduction pathways that regulate cell survival and cell death

1998 • 187 citations

Colchicine Induces Apoptosis in Cerebellar Granule Cells

1995 • 143 citations

β4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent

1994 • 143 citations

Evidence that matrix recognition contributes to stabilization but not induction of LTP

1991 • 135 citations

Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells.

1997 • 132 citations

An inhibitor of integrin receptors blocks long-term potentiation

1990 • 128 citations

Genetic analyses of integrin function in mice

1996 • 124 citations

Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms.

1990 • 116 citations

Integrin αvβ3-Mediated Activation of Apoptosis

1999 • 100 citations

Up-regulation of the integrin alpha 1/beta 1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin.

1991 • 97 citations

The α5β1 Integrin Mediates Elimination of Amyloid-β Peptide and Protects Against Apoptosis

1998 • 97 citations

Cell Surface Amyloid β-Protein Precursor Colocalizes with β1 Integrins at Substrate Contact Sites in Neural Cells

1997 • 95 citations

Integrins: possible functions in the adult CNS

1996 • 95 citations

Cytochrome c release and caspase‐3 activation during colchicine‐induced apoptosis of cerebellar granule cells

1999 • 78 citations

Induction of apoptosis in human neuroblastoma cells by abrogation of integrin-mediated cell adhesion

1997 • 66 citations

pp125FAK in the Focal Adhesion

1996 • 62 citations

B Cell Apoptosis Triggered by Antigen Receptor Ligation Proceeds Via a Novel Caspase-Dependent Pathway

1999 • 58 citations

Expression of a beta 1-related integrin by oligodendroglia in primary culture: evidence for a functional role in myelination

1994 • 51 citations

Expression of integrin receptors on 45 clinical neuroblastoma specimens

1991 • 45 citations

Protein kinase C isoenzymes in human neuroblasts involvement of PKCε in cell differentiation

1993 • 41 citations

Phosphorylation‐Dependent Akt Cleavage in Neural Cell In Vitro Reconstitution of Apoptosis

1999 • 38 citations

Uncoordinate induction and differential regulation of hla class‐I and class‐II expression by γ‐interferon in differentiating human neuroblastoma cells

1993 • 37 citations

Modulation of α₁ β₁, α₂β₁, and α₃β₁ integrin heterodimers during human neuroblastoma cell differentiation

1993 • 27 citations

Interferon-γ-stimulated and GTP-binding-proteins-mediated phospholipase A2 activation in human neuroblasts

1993 • 23 citations

Understanding the Molecular Basis of Cell Migration; Implications for Clinical Therapy in Multiple Sclerosis

1997 • 22 citations

B-myb Transcriptional Regulation and mRNA Stability during Differentiation of Neuroblastoma Cells

1996 • 15 citations

Induction of 2,5 oas gene expression and activity is not sufficient for IFN‐γ‐induced neuroblastoma cell differentiation

1995 • 10 citations