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Integrins: possible functions in the adult CNS

Data up to Jan 2025

Published1996
Citations95
References75

Total Citations Per Year

Abstract

References (75)

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

1994 • 557 citations

Extracellular Matrix Molecules that Influence Neural Development

1989 • 537 citations

Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice

1984 • 531 citations

Brief bursts of high-frequency stimulation produce two types of structural change in rat hippocampus.

1980 • 474 citations

Early penetration of the blood-brain-barrier by HIV.

1988 • 444 citations

Brain glia release factors with opposing actions upon neuronal survival

1993 • 437 citations

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells.

1991 • 420 citations

Integrin α2β1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells

1991 • 379 citations

Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia

1992 • 377 citations

Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alterations of the blood‐brain barrier

1993 • 333 citations

Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia

1992 • 313 citations

Laminin-immunoreactive glia distinguish regenerative adult CNS systems from non-regenerative ones.

1985 • 298 citations

Molecular forms, binding functions, and developmental expression patterns of cytotactin and cytotactin-binding proteoglycan, an interactive pair of extracellular matrix molecules

1988 • 276 citations

Blood‐brain barrier abnormalities in acquired immunodeficiency syndrome: Immunohistochemical localization of serum proteins in postmortem brain

1992 • 275 citations

Vitronectin and thrombospondin promote retinal neurite outgrowth: Developmental regulation and role of integrins

1991 • 237 citations

The participation of a putative cell surface receptor for laminin and fibronectin in peripheral neurite extension

1986 • 223 citations

Characterization of integrin receptors in normal and neoplastic human brain.

1993 • 221 citations

Changes in the numerical density of synaptic contacts with long‐term potentiation in the hippocampal dentate gyrus

1986 • 210 citations

Perturbation of cranial neural crest migration by the HNK-1 antibody

1987 • 173 citations

Characterization of the integrin alpha 8 subunit: a new integrin beta 1-associated subunit, which is prominently expressed on axons and on cells in contact with basal laminae in chick embryos.

1991 • 161 citations

Human microglial cells: Characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV‐1 infection

1991 • 156 citations

Changes in the structure of synapses associated with learning

1985 • 152 citations

Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat.

1991 • 145 citations

The NC1 domain of type IV collagen promotes axonal growth in sympathetic neurons through interaction with the alpha 1 beta 1 integrin.

1991 • 136 citations

Evidence that matrix recognition contributes to stabilization but not induction of LTP

1991 • 135 citations

Calcium signaling capacity of the integrin on human neutrophils

1991 • 135 citations

An inhibitor of integrin receptors blocks long-term potentiation

1990 • 128 citations

Microglial and astroglial reactions to anterograde axonal degeneration: a histochemical and immunocytochemical study of the adult rat fascia dentata after entorhinal perforant path lesions

1994 • 127 citations

Immunohistochemical localization of vitronectin, its receptor and beta-3 integrin in Alzheimer brain tissue

1991 • 122 citations

Neural crest cell locomotion induced by antibodies to β1 integrins A tool for studying the roles of substratum molecular avidity and density in migration

1991 • 106 citations

Increase in the number of axospinous synapses with segmented postsynaptic densities following hippocampal kindling

1992 • 105 citations

Monocyte adhesion to endothelium in simian immunodeficiency virus-induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/alpha 4 beta 1 integrin interactions.

1994 • 101 citations

Fibronectin and laminin regulate thein vitro differentiation of microglial cells

1991 • 98 citations

Transforming growth factor β1 and fibronectin messenger RNA in rat brain: Responses to injury and cell-type localization

1993 • 96 citations

Microglia with an Endothelin ETB Receptor Aggregate in Rat Hippocampus CA1 Subfields Following Transient Forebrain Ischemia

1994 • 93 citations

Effect of anisomycin on stimulation-induced changes in dendritic spines of the dentate granule cells

1982 • 91 citations

Reactions of the Immune System in Chronic Degenerative Neurological Diseases

1991 • 87 citations

The role of brain extracellular proteins in neuroplasticity and learning

1985 • 82 citations

Mitosis and apoptosis of microgliain vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier

1993 • 78 citations

Regrowth of motor axons following spinal cord lesions: Distribution of laminin and collagen in the CNS scar tissue

1993 • 76 citations

The Complex Nature of Interactive Neuroregeneration-Related Molecules

1993 • 73 citations

Anti-S-100 Serum blocks long-term potentiation in the hippocampal slice

1986 • 72 citations

Loss of axosomatic synapses in the dentate gyrus of aged rats

1979 • 69 citations

Comparison of gene expression of extracellular matrix molecules in brain microvascular endothelial cells and astrocytes

1992 • 69 citations

Integrins : molecular and biological responses to the extracellular matrix

1994 • 66 citations

Anatomical Localization of β1 Integrin-like Immunoreactivity in Rat Brain

1993 • 66 citations

Glutamate, Cell Death and Memory

1991 • 62 citations

Functional elongation of CA1 hippocampal neurons with aging in Fischer 344 rats

1991 • 54 citations

Proliferative astrocytes may express fibronectin-like protein in the hippocampus of epileptic rats

1994 • 51 citations

Expression of integrin receptors on 45 clinical neuroblastoma specimens

1991 • 45 citations

Evidence that the B2 chain of laminin is responsible for the neurite outgrowth-promoting activity of astrocyte extracellular matrix

1990 • 44 citations

Purification of an Arg-Gly-Asp selective matrix receptor from brain synaptic plasma membranes

1992 • 37 citations

Synaptic structural plasticity following repetitive activation in the rat hippocampus

1989 • 34 citations

MHC Class II expression by microglia in tetanus toxin–induced experimental epilepsy in the rat

1994 • 32 citations

Fibronectin immunoreactivity in neural trauma

1991 • 32 citations

Development of anin vitro extracellular matrix assay for studies of brain tumor cell invasion

1994 • 28 citations

Nefiracetam (DM‐9384) Preserves Hippocampal Neural Cell Adhesion Molecule‐Mediated Memory Consolidation Processes During Scopolamine Disruption of Passive Avoidance Training in the Rat

1993 • 28 citations

Astrocytic and synaptic response to kindling in hippocampal subfield CA1. I. Synaptogenesis in response to kindling in vitro

1993 • 27 citations

Sequential effects of astroglial‐derived factors on neurite outgrowth: Initiation by protease inhibitors and potentiation by extracellular matrix components

1992 • 26 citations

Integrins: Molecular and biological responses to the extracellular matrix

1995 • 26 citations

Calcium channel blocker treatment of tumor cells induces alterations in the cytoskeleton, mobility of the integrin αIIbβ3 and tumor-cell-induced platelet aggregation

1992 • 24 citations

Intraneuronal laminin-like immunoreactivity in the human central nervous system

1990 • 19 citations

Antibodies to the αvβ3 integrin label a protein concentrated in brain synaptosomal membranes

1991 • 14 citations

Repression of Integrin .BETA.1 Subunit Expression by Antisense RNA.

1991 • 13 citations

Evidence that the V+ fibronectin mRNA is increased in the hippocampus of aged rats

1991 • 11 citations

Integrin-mediated cell-matrix interactions in heart development and disease

1993 • 10 citations

Alternative Splicing of Fibronectin Pre‐mRNA during Aginga

1992 • 5 citations

Expression of Chicken Integrin .BETA.1 Subunit in Rat PC12 Cells.

1991 • 3 citations

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Integrins: possible functions in the adult CNS (1996) – Trends in Neurosciences | Metascience Observatory Explorer