Control of adhesion-dependent cell survival by focal adhesion kinase.

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1995 • 1,810 citations

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1994 • 1,590 citations

The extracellular matrix as a cell survival factor.

1993 • 1,541 citations

Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix

1995 • 1,184 citations

Anchorage dependence, integrins, and apoptosis

1994 • 1,016 citations

Activation of Raf as a Result of Recruitment to the Plasma Membrane

1994 • 979 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis

1994 • 820 citations

Integrin-mediated cell adhesion activates mitogen-activated protein kinases.

1994 • 660 citations

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression.

1995 • 627 citations

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.

1995 • 620 citations

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors.

1995 • 619 citations

Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

1995 • 601 citations

pp125^FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for Crk

1995 • 534 citations

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1994 • 525 citations

Focal adhesion kinase and associated proteins

1994 • 525 citations

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway

1994 • 458 citations

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas.

1995 • 423 citations

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

1993 • 408 citations

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.

1995 • 324 citations

Signal transduction through integrins: A central role for focal adhesion kinase?

1995 • 273 citations

Adhesion molecules in cancer: the role of integrins

1993 • 264 citations

Apoptosis in human skin development: Morphogenesis, periderm, and stem cells

1994 • 259 citations

Paradoxical inhibition of solid tumor cell growth by bcl2.

1994 • 190 citations

Integrating with integrins.

1994 • 189 citations

A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK.

1994 • 134 citations

Stable association of pp60^src and pp59^fyn with the focal adhesion-associated protein tyrosine kinase, pp125^FAK

1994 • 119 citations

Antioncogenic effect of adenovirus E1A in human tumor cells.

1991 • 112 citations

Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+

1993 • 102 citations

Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2

1987 • 22 citations