PRL1 Promotes Cell Migration and Invasion by Increasing MMP2 and MMP9 Expression through Src and ERK1/2 Pathways

Matrix metalloproteinases and tumor metastasis

2006 • 1,908 citations

Protein tyrosine phosphatases: from genes, to function, to disease

2006 • 1,587 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis

2002 • 879 citations

A Phosphatase Associated with Metastasis of Colorectal Cancer

2001 • 641 citations

Type IV collagenases in tumor invasion and metastasis

1990 • 502 citations

Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response

2004 • 487 citations

THE CROONIAN LECTURE 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease

1998 • 401 citations

Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

1998 • 368 citations

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences

1996 • 351 citations

The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells

2006 • 333 citations

Matrix Metalloproteinase 2 (MMP2) and MMP9 Secreted by Erythropoietin-Activated Endothelial Cells Promote Neural Progenitor Cell Migration

2006 • 304 citations

Integrin signalling: a new Cas(t) of characters enters the stage

2000 • 298 citations

Identification of Two Sp1 Phosphorylation Sites for p42/p44 Mitogen-activated Protein Kinases

2002 • 293 citations

v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.

1993 • 291 citations

Hepatitis B viral HBx induces matrix metalloproteinase‐9 gene expression through activation of ERKs and PI‐3K/AKT pathways: Involvement of invasive potential

2004 • 290 citations

Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition

2005 • 284 citations

Transcriptional Activation by p53 of the Human Type IV Collagenase (Gelatinase A or Matrix Metalloproteinase 2) Promoter

1997 • 278 citations

PRL-3 and PRL-1 promote cell migration, invasion, and metastasis.

2003 • 275 citations

A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun

2003 • 270 citations

The Transcription Factors Sp1, Sp3, and AP-2 Are Required for Constitutive Matrix Metalloproteinase-2 Gene Expression in Astroglioma Cells

1999 • 267 citations

PRL-1, a Unique Nuclear Protein Tyrosine Phosphatase, Affects Cell Growth

1994 • 254 citations

PRL-3 Down-regulates PTEN Expression and Signals through PI3K to Promote Epithelial-Mesenchymal Transition

2007 • 251 citations

Sustained Activation of the Mitogen-activated Protein Kinase Pathway

1999 • 205 citations

KiSS-1 Represses 92-kDa Type IV Collagenase Expression by Down-regulating NF-κB Binding to the Promoter as a Consequence of IκBα-induced Block of p65/p50 Nuclear Translocation

2001 • 198 citations

PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility

2006 • 184 citations

High Expression of PRL-3 Promotes Cancer Cell Motility and Liver Metastasis in Human Colorectal Cancer

2004 • 164 citations

PRL3 Promotes Cell Invasion and Proliferation by Down-regulation of Csk Leading to Src Activation

2006 • 158 citations

The Contribution of Bone Marrow–Derived Cells to the Tumor Vasculature in Neuroblastoma Is Matrix Metalloproteinase-9 Dependent

2005 • 155 citations

PRL phosphatases as potential molecular targets in cancer

2005 • 145 citations

Status of the transcription factors database (TFD)

1993 • 125 citations

The Tyrosine Phosphatase PRL-1 Localizes to the Endoplasmic Reticulum and the Mitotic Spindle and Is Required for Normal Mitosis

2002 • 119 citations

Regulation of Tumor Cell Motility by ERK Mitogen‐Activated Protein Kinases

2004 • 87 citations

PRL-1 Tyrosine Phosphatase Regulates c-Src Levels, Adherence, and Invasion in Human Lung Cancer Cells

2007 • 85 citations

Enhanced cell cycle progression and down regulation of p21Cip1/Waf1 by PRL tyrosine phosphatases

2003 • 82 citations

Src oncogene activates MMP‐2 expression via the ERK/Sp1 pathway

2006 • 78 citations

Phosphatase Activity, Trimerization, and the C-terminal Polybasic Region Are All Required for PRL1-mediated Cell Growth and Migration

2007 • 78 citations

Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors

1999 • 53 citations

Phosphorylation of SIMPL modulates RelA-associated NF-κB-dependent transcription

2006 • 8 citations