PRL-1 Tyrosine Phosphatase Regulates c-Src Levels, Adherence, and Invasion in Human Lung Cancer Cells

Cancer Statistics, 2005

2005 • 5,487 citations

Focal adhesion kinase: in command and control of cell motility

2005 • 2,405 citations

Tyrosine Phosphorylation of Focal Adhesion Kinase at Sites in the Catalytic Domain Regulates Kinase Activity: a Role for Src Family Kinases

1995 • 989 citations

Cell–matrix adhesion

2007 • 885 citations

CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration

1998 • 668 citations

A Phosphatase Associated with Metastasis of Colorectal Cancer

2001 • 641 citations

Protein-tyrosine phosphatases and cancer

2006 • 638 citations

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

1998 • 615 citations

Rho-family GTPases: it's not only Rac and Rho (and I like it)

2004 • 599 citations

Rho GTPases: Signaling, Migration, and Invasion

2000 • 584 citations

Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

2002 • 569 citations

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

2002 • 405 citations

PRL-3 and PRL-1 promote cell migration, invasion, and metastasis.

2003 • 275 citations

Identification of p130^cas as a Substrate for the Cytosolic Protein Tyrosine Phosphatase PTP-PEST

1996 • 263 citations

PRL-1, a Unique Nuclear Protein Tyrosine Phosphatase, Affects Cell Growth

1994 • 254 citations

The immediate-early growth response in regenerating liver and insulin-stimulated H-35 cells: comparison with serum-stimulated 3T3 cells and identification of 41 novel immediate-early genes.

1991 • 216 citations

Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior

2005 • 213 citations

Prenylation of oncogenic human PTPcaax protein tyrosine phosphatases

1996 • 209 citations

PRL-3 expression in metastatic cancers.

2003 • 201 citations

Prenylation-dependent Association of Protein-tyrosine Phosphatases PRL-1, -2, and -3 with the Plasma Membrane and the Early Endosome

2000 • 201 citations

PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility

2006 • 184 citations

Mouse PRL-2 and PRL-3, Two Potentially Prenylated Protein Tyrosine Phosphatases Homologous to PRL-1

1998 • 180 citations

Direct Association of Protein-tyrosine Phosphatase PTP-PEST with Paxillin

1998 • 176 citations

High Expression of PRL-3 Promotes Cancer Cell Motility and Liver Metastasis in Human Colorectal Cancer

2004 • 164 citations

Phosphatases in cell–matrix adhesion and migration

2003 • 146 citations

PRL phosphatases as potential molecular targets in cancer

2005 • 145 citations

The Tyrosine Phosphatase PRL-1 Localizes to the Endoplasmic Reticulum and the Mitotic Spindle and Is Required for Normal Mitosis

2002 • 119 citations

p130CAS Forms a Signaling Complex with the Adapter Protein CRKL in Hematopoietic Cells Transformed by the BCR/ABL Oncogene

1996 • 114 citations

C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)—endogenous negative regulators of Src-family protein kinases

2005 • 102 citations

Crk Associates with a Multimolecular Paxillin/GIT2/β-PIX Complex and Promotes Rac-dependent Relocalization of Paxillin to Focal Contacts

2003 • 98 citations

Functional analysis of Csk in signal transduction through the B-cell antigen receptor.

1994 • 91 citations

Enhanced cell cycle progression and down regulation of p21Cip1/Waf1 by PRL tyrosine phosphatases

2003 • 82 citations

Identification of integrin α1 as an interacting protein of protein tyrosine phosphatase PRL-3

2006 • 73 citations

PTP-PEST Couples Membrane Protrusion and Tail Retraction via VAV2 and p190RhoGAP

2006 • 68 citations

GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover

2006 • 66 citations

Regulation of Cell Adhesion by Protein-tyrosine Phosphatases

2006 • 65 citations

The Immediate-Early Growth Response in Regenerating Liver and Insulin-Stimulated H-35 Cells: Comparison with Serum-Stimulated 3T3 Cells and Identification of 41 Novel Immediate-Early Genes

1991 • 59 citations

Expression of PRL-1 nuclear PTPase is associated with proliferation in liver but with differentiation in intestine

1996 • 48 citations