CNS effects of heavy particle irradiation in space: Behavioral implications

Inositol phosphates and cell signalling

1989 • 4,058 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Ginkgo Biloba

1996 • 622 citations

Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers

1988 • 512 citations

Ginkgo biloba

1992 • 451 citations

Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores

1991 • 366 citations

Ginkgo biloba for cerebral insufficiency.

1992 • 342 citations

Receptor Activation and Inositol Lipid Hydrolysis in Neural Tissues

1987 • 341 citations

Guidance on Radiation Received in Space Activities

1990 • 224 citations

Differential Regulation of Molecular Subtypes of Muscarinic Receptors in Alzheimer's Disease

1995 • 221 citations

Myricetin and quercetin, the flavonoid constituents ofGinkgo biloba extract, greatly reduce oxidative metabolism in both resting and Ca2+-loaded brain neurons

1994 • 213 citations

Reduced Phosphoinositide Concentrations in Anterior Temporal Cortex of Alzheimer‐Diseased Brains

1987 • 201 citations

The effect of ionizing radiation on lipid membranes

1991 • 183 citations

The Basal ganglia : structure and function

1984 • 161 citations

Structural and functional relationships of heterotrimeric G‐proteins

1995 • 160 citations

Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging

1995 • 155 citations

A double-blind, placebo controlled study of Ginkgo biloba extract (‘Tanakan’) in elderly outpatients with mild to moderate memory impairment

1991 • 146 citations

Loss of high‐affinity agonist binding to M1 muscarinic receptors in Alzheimer's disease: Implications for the failure of cholinergic replacement therapies

1991 • 145 citations

Possible Äccelerated Striatal Aging" Induced by 56 Fe Heavy-Particle Irradiation: Implications for Manned Space Flights

1992 • 135 citations

Role of membrane lipid asymmetry in aging

1984 • 131 citations

Terrestrial Space Radiation and Its Biological Effects

1988 • 117 citations

Decreased brain [3H]inositol 1,4,5-trisphosphate binding in Alzheimer's disease

1988 • 102 citations

Decreased cerebral 5-HT1A receptors during ageing: reversal by Ginkgo biloba extract (EGb 761)

1994 • 91 citations

Effects of an extract of Ginkgo biloba on learning and memory in mice

1991 • 89 citations

Intracellular calcium waves generated by ins(1,4,5)P3-dependent mechanisms

1993 • 83 citations

Multiple mechanisms of receptor-G protein signaling specificity

1995 • 78 citations

Receptor-operated Ca2+ signaling and crosstalk in stimulus secretion coupling

1993 • 75 citations

Age-related decrements in the muscarinic enhancement of K+-evoked release of endogenous striatal dopamine: an indicator of altered cholinergic-dopaminergic reciprocal inhibitory control in senescence

1988 • 74 citations

Impaired phosphoinositide hydrolysis in Alzheimer's disease brain

1994 • 74 citations

Age differences in sensitivity to H2O2- or no-induced reductions in K+-evoked dopamine release from superfused striatal slices: Reversals by PBN or Trolox

1996 • 72 citations

Effect of long-term treatment with EGb 761 on age-dependent structural changes in the hippocampi of three inbred mouse strains

1994 • 64 citations

Deficits in the Sensitivity of Striatal Muscarinic Receptors Induced by 56 Fe Heavy-Particle Irradiation: Further Äge-Radiation" Parallels

1993 • 60 citations

Alterations in muscarinic control of striatal dopamine autoreceptors in senescence: a deficit at the ligand-muscarinic receptor interface?

1988 • 60 citations

Unique biological aspects of radiation hazards — An overview

1983 • 59 citations

Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata

1990 • 58 citations

Alzheimer's disease: is there a problem beyond recognition?

1990 • 50 citations

Decrement of muscarinic receptor-stimulated low-KMGTPase in striatum and hippocampus from the aged rat

1992 • 50 citations

Improving Effects of FG-7080, a Serotonin Reuptake Inhibitor, on Scopolamine-Induced Performance Deficits of Memory Tasks in Rats

1993 • 41 citations

Decreased efficacy of inositol 1,4,5-trisphosphate to elicit calcium mobilization from cerebrocortical microsomes of aged rats.

1990 • 39 citations

Area specific alterations in muscarinic stimulated low Km GTPase activity in aging and Alzheimer's disease: implications for altered signal transduction

1994 • 34 citations

Reductions of 56 Fe Heavy-Particle Irradiation-Induced Deficits in Striatal Muscarinic Receptor Sensitivity by Selective Cross-Activation/Inhibition of Second-Messenger Systems

1994 • 31 citations

Disturbances in signal transduction mechanisms in Alzheimer's disease

1995 • 30 citations

Disturbances in signal transduction mechanisms in Alzheimer’s disease

1995 • 27 citations

Age-specific alterations in muscarinic stimulation of K+-evoked dopamine release from striatal slices by cholesterol andS-adenosyl-l-methionine

1995 • 23 citations

Iron-56 Irradiation Diminishes Muscarinic but Not α 1 -Adrenergic-Stimulated Low-K m GTPase in Rat Brain

1994 • 22 citations

Guanine nucleotide binding regulatory proteins: Their characteristics and identification

1994 • 17 citations

Basal ganglia: Structure and function

1998 • 11 citations

On the Origins and Present State of the Art of G Protein Research

1991 • 7 citations

Techniques for fine gamma-ray burst spectroscopy

1983 • 3 citations