Decrement of muscarinic receptor-stimulated low-KMGTPase in striatum and hippocampus from the aged rat

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G _q

1991 • 886 citations

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

1991 • 774 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

A nucleotide regulatory site for somatostatin inhibition of adenylate cyclase in S49 lymphoma cells

1983 • 200 citations

Identification of the GTP-binding protein encoded by Gi3 complementary DNA.

1988 • 169 citations

Use of specific antibodies to quantitate the guanine nucleotide-binding protein Go in brain.

1986 • 158 citations

Loss of high‐affinity agonist binding to M1 muscarinic receptors in Alzheimer's disease: Implications for the failure of cholinergic replacement therapies

1991 • 145 citations

Role of membrane lipid asymmetry in aging

1984 • 131 citations

Drugs to Treat Age‐Related Neurodegenerative Problems The Final Frontier of Medical Science?

1990 • 88 citations

Age-related decrements in the muscarinic enhancement of K+-evoked release of endogenous striatal dopamine: an indicator of altered cholinergic-dopaminergic reciprocal inhibitory control in senescence

1988 • 74 citations

Guanine nucleotide modulation of muscarinic cholinergic receptor binding in postmortem human brain — A preliminary study in Alzheimer's disease

1987 • 64 citations

Tetrahydroaminoacridine, 3,4 diaminopyridine and physostigmine: Direct comparison of effects on memory in aged primates

1988 • 62 citations

Alterations in muscarinic control of striatal dopamine autoreceptors in senescence: a deficit at the ligand-muscarinic receptor interface?

1988 • 60 citations

Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata

1990 • 58 citations

Agonist and antagonist binding to rat brain muscarinic receptors: Influence of aging

1987 • 55 citations

Alzheimer's disease: is there a problem beyond recognition?

1990 • 50 citations

Effect of acute arecoline, tacrine and arecoline + tacrine post-training administration on retention in old mice

1988 • 48 citations

Molecular Basis of Regulation of Ionic Channels by G Proteins

1989 • 24 citations

Differential coupling between muscarinic receptors and G-proteins in regions of the rat brain

1990 • 23 citations

Muscarinic receptor concentrations and dopamine release in aged rat striata

1992 • 22 citations

Characterization of Low Km GTPase Activity in Rat Brain: Comparison of Opioid and Muscarinic Receptor Stimulation

1988 • 20 citations