The mast cell and mast cell disease

Histopathology of the skin

1975 • 2,630 citations

Textbook of dermatology

1968 • 1,648 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

Prostaglandins and Thromboxanes

1978 • 1,310 citations

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 • 1,199 citations

New Concepts about the Mast Cell

1993 • 1,009 citations

Leukotriene C: a slow-reacting substance from murine mastocytoma cells.

1979 • 992 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

Tryptase Levels as an Indicator of Mast-Cell Activation in Systemic Anaphylaxis and Mastocytosis

1987 • 775 citations

Mast cells as a source of multifunctional cytokines

1990 • 708 citations

Human dermal mast cells contain and release tumor necrosis factor alpha, which induces endothelial leukocyte adhesion molecule 1.

1991 • 626 citations

New Insights into “The Riddle of the Mast Cells”: Microenvironmental Regulation of Mast Cell Development and Phenotypic Heterogeneity

1990 • 625 citations

Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines.

1989 • 557 citations

The mast cells

1965 • 520 citations

Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells.

1987 • 504 citations

Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation

1989 • 494 citations

Systemic Mast Cell Disease

1988 • 485 citations

Heterogeneity of Mast Cells and Phenotypic Change Between Subpopulations

1989 • 484 citations

Histopathology of the Skin

1990 • 453 citations

Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis.

1989 • 450 citations

Slow reacting substances of anaphylaxis: Identification of leukotrienes C-1 and D from human and rat sources

1980 • 433 citations

Increased Production of Prostaglandin D2 in Patients with Systemic Mastocytosis

1980 • 430 citations

Tryptase from human pulmonary mast cells. Purification and characterization.

1981 • 428 citations

Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor.

1991 • 424 citations

Bronchoconstrictor Effects of Leukotriene C in Humans

1982 • 404 citations

The mast cell.

1981 • 399 citations

Stereospecific total synthesis of a "slow reacting substance" of anaphylaxis, leukotriene C-1

1980 • 369 citations

Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells.

1991 • 369 citations

Recent advances in the cellular and molecular biology of mast cells

1989 • 366 citations

Mast cells increase in tissues of neonatal rats injected with the nerve growth factor

1977 • 357 citations

Classification and Diagnosis of Mastocytosis: Current Status

1991 • 353 citations

Cytokine production by mast cells and basophils

1991 • 344 citations

Beiträge zur Kenntniss der Anilinfärbungen und ihrer Verwendung in der mikroskopischen Technik

1877 • 334 citations

Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells.

1981 • 332 citations

Human intestinal mucosal mast cells: evaluation of fixation and staining techniques.

1981 • 319 citations

Substance P regulates the vasodilator activity of calcitonin gene-related peptide

1988 • 306 citations

Human mast cells produce IL-8.

1993 • 302 citations

Structure and Function of the Chemical Mediators of Mast Cells

2015 • 295 citations

Effect of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34+ pluripotent progenitor cells.

1992 • 289 citations

The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype.

1991 • 288 citations

Slow-reacting substances (leukotrienes) contract human airway and pulmonary vascular smooth muscle in vitro

1981 • 285 citations

Bone marrow findings in systemic mastocytosis

1985 • 263 citations

Altered Metabolism of Mast-Cell Growth Factor (c-kit Ligand) in Cutaneous Mastocytosis

1993 • 261 citations

Response to Interferon Alfa-2b in a Patient with Systemic Mastocytosis

1992 • 230 citations

Oral Disodium Cromoglycate in the Treatment of Systemic Mastocytosis

1979 • 229 citations

The Natural Course of Urticaria Pigmentosa

1963 • 219 citations

Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell.

1990 • 207 citations

Tissue mast cells in health and disease

1985 • 201 citations

Systemic Mastocytosis: Retrospective Review of a Decade's Clinical Experience at the Brigham and Women's Hospital

1991 • 200 citations

Systemic mast cell disease: A clinical and hematopathologic study of 26 cases

1982 • 198 citations

Degradation of the epidermal-dermal junction by proteolytic enzymes from human skin and human polymorphonuclear leukocytes.

1984 • 193 citations

Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs.

1989 • 181 citations

Improved Diagnosis of Mastocytosis by Measurement of Urinary Hist Amine Metabolites

1983 • 175 citations

AN ENZYME IN MAST CELLS WITH PROPERTIES LIKE CHYMOTRYPSIN

1959 • 171 citations

Mastocytosis and the Mast Cell

1968 • 167 citations

Mast Cell Leukemia: Report of a Case and Review of the Literature

1986 • 163 citations

The Mastocytosis Syndrome: Clinical and Biological Studies

1963 • 162 citations

Ultrastructural analysis of human T and TC mast cells identified by immunoelectron microscopy.

1988 • 160 citations

Human mast cell carboxypeptidase. Selective localization to MCTC cells.

1991 • 159 citations

Mast Cell and Basophil Differentiation and Function in Health and Disease

1989 • 159 citations

Cromolyn sodium in the management of systemic mastocytosis

1990 • 158 citations

Urticaria pigmentosa; a report of a case with autopsy.

1949 • 151 citations

The Skin in Mastocytosis

1991 • 146 citations

Intravascular Aggregation and Pulmonary Sequestration of Platelets during IgE-Induced Systemic Anaphylaxis in the Rabbit: Abrogation of Lethal Anaphylactic Shock by Platelet Depletion

1977 • 145 citations

Gastrointestinal Dysfunction in Systemic Mastocytosis

1988 • 144 citations

Systemic mastocytosis

1983 • 139 citations

Mastocytosis and the Mast Cell

1967 • 136 citations

Reversible expansion of primate mast cell populations in vivo by stem cell factor.

1993 • 127 citations

Protease composition of exocytosed human skin mast cell protease-proteoglycan complexes. Tryptase resides in a complex distinct from chymase and carboxypeptidase.

1992 • 125 citations

The Treatment of Mastocytosis: An Overview

1991 • 125 citations

Inactivation of human high molecular weight kininogen by human mast cell tryptase.

1983 • 119 citations

Monoclonal antibodies against human mast cell tryptase demonstrate shared antigenic sites on subunits of tryptase and selective localization of the enzyme to mast cells.

1985 • 118 citations

Human skin chymotrypsin-like proteinase chymase. Subcellular localization to mast cell granules and interaction with heparin and other glycosaminoglycans.

1987 • 118 citations

PUVA-treatment of urticaria pigmentosa

1978 • 118 citations

Rare forms of urticaria

1869 • 109 citations

Comparison of the therapeutic efficacy of cromolyn sodium with that of combined chlorpheniramine and cimetidine in systemic mastocytosis. Results of a double-blind clinical trial

1985 • 109 citations

Histologic Diagnosis of Inflammatory Skin Diseases: A Method by Pattern Analysis

1978 • 107 citations

The role of mast cells in demyelination. 1. Myelin proteins are degraded by mast cell proteases and myelin basic protein and P2 can stimulate mast cell degranulation

1988 • 106 citations

Histologic Diagnosis of Inflammatory Skin Diseases: A Method by Pattern Analysis

1979 • 104 citations

Mouse mast cells as anti-tumor effector cells

1980 • 97 citations

Photochemotherapy (PUVA) in the treatment of urticaria pigmentosa

1983 • 95 citations

Mast cell tryptase and chymase reverse airway smooth muscle relaxation induced by vasoactive intestinal peptide in the ferret.

1989 • 94 citations

Treatment of Urticaria Pigmentosa With Corticosteroids

1985 • 90 citations

Anaphylaxis after hymenoptera stings in three patients with urticaria pigmentosa

1983 • 87 citations

Mastocytosis: A Review

1986 • 86 citations

Effect of Cimetidine on Gastric Hypersecretion and Diarrhea in Systemic Mastocytosis

1979 • 85 citations

Detection and partial characterization of a human mast cell carboxypeptidase.

1987 • 84 citations

Immunoassay of tryptase from human mast cells

1986 • 80 citations

Intervention with epinephrine in hypotension associated with mastocytosis

1983 • 78 citations

Decreased Urinary Histamine Metabolite after Successful PUVA Treatment of Urticaria Pigmentosa

1981 • 76 citations

Studies on Histamine Metabolism in Mastocytosis

1983 • 74 citations

Biochemical Diagnosis of Systemic Mast Cell Disorders

1991 • 72 citations

HISTOCHEMICAL LOCALIZATION OF β-GLUCURONIDASE AND N-ACETYL-β-GLUCOSAMINIDASE

1961 • 72 citations

Mastocytosis and the mast cell

1982 • 71 citations

Bullous Mastocytosis: Diffuse Cutaneous Mastocytosis with Extensive Blisters Mimicking Scalded Skin Syndrome or Erythema Multiforme

1984 • 67 citations

Pigmentation and Proliferation of Human Melanocytes and the Effects of Melanocyte‐Stimulating Hormone and Ultraviolet B Light^a

1993 • 65 citations

Mixed organic brain syndrome as a manifestation of systemic mastocytosis.

1986 • 65 citations

Hazards in Operative Management of Patients with Systemic Mastocytosis

1983 • 62 citations

Hepatic involvement in systemic mast cell disease

1986 • 60 citations

Mast cell chymase potentiates histamine-induced wheal formation in the skin of ragweed-allergic dogs.

1990 • 59 citations

Hematopathology of the Bone Marrow in Pediatric Cutaneous Mastocytosis: A Study of 17 Patients

1989 • 58 citations

Hematologic Aspects of Mastocytosis: I: Bone Marrow Pathology in Adult and Pediatric Systemic Mast Cell Disease

1991 • 57 citations

Mastocytosis without urticaria pigmentosa: a frequently unrecognized cause of recurrent syncope.

1982 • 56 citations

Identification of Sulfated Mucopolysaccharides Including Heparin in the Lesional Skin of a Patient with Mastocytosis

1980 • 56 citations

Mast cell infiltrates of the skin and the mastocytosis syndrome

1973 • 55 citations

The Mast Cell in Health and Disease

1993 • 55 citations

Urticaria pigmentosa: Treatment with cimetidine andchlorpheniramine

1979 • 54 citations

Mastocytosis

1980 • 51 citations

Localization of carboxypeptidase A to the macromolecular heparin proteoglycan-protein complex in secretory granules of rat serosal mast cells.

1982 • 50 citations

AN UNUSUAL CAUSE OF PAIN AND HAEMATURIA

1928 • 50 citations

Genetic Aspects of Urticaria Pigmentosa

1968 • 50 citations

The Diversity Of Mast Cell-Derived Mediators: Implications For Acute, Subacute, And Chronic Cutaneous Inflammatory Disorders

1976 • 48 citations

Cutaneous mastocytosis in children: anaesthetic considerations

1987 • 47 citations

Solitary Mastocytosis (Urticaria Pigmentosa)

1961 • 46 citations

Effects of Metiamide on Gastric Acid Hypersecretion, Steatorrhea and Bone-Marrow Function in a Patient with Systemic Mastocytosis

1976 • 44 citations

Role of the chemoreceptor trigger zone in histamine‐induced emesis

1968 • 44 citations

Familial Urticaria Pigmentosa

1986 • 42 citations

Generalized Flushing of the Skin with Urticaria Pigmentosa

1959 • 42 citations

IgE-induced respiratory and circulatory changes during systemic anaphylaxis in the rabbit.

1976 • 41 citations

Adult-onset Urticaria Pigmentosa and Systemic Mast Cell Disease

1985 • 40 citations

Heparin Activity in Systemic Mastocytosis

1979 • 40 citations

Splenectomy in the management of systemic mast cell disease.

1990 • 39 citations

Chemistry and Storage Function of Mast Cell Granules

1978 • 36 citations

Hematologic malignancies occurring in patients with urticaria pigmentosa

1982 • 36 citations

Evidence for morphologic diversity of human mast cells. An ultrastructural study of mast cells from multiple body sites.

1990 • 34 citations

Mastocytosis and intestinal malabsorption

1970 • 33 citations

Slow Reacting Substance

1965 • 32 citations

Mastocytosis with Skeletal and Gastrointestinal Involvement in Infancy

1979 • 32 citations

Shock in an Infant with Bullous Mastocytosis

1989 • 28 citations

Pseudoxanthomatous mastocytosis

1975 • 28 citations

Histamine2 (H2)-Receptor Antagonists in the Treatment of Urticaria

1989 • 27 citations

The mast cell in health and disease

1993 • 25 citations

Systemic mastocytosis with portal hypertension. Autopsy findings and ultrastructural study of the liver.

1985 • 25 citations

Familial Urticaria Pigmentosa With Giant Mast Cell Granules

1981 • 24 citations

Characterization of cellular dermal infiltrates in human cutaneous mastocytosis.

1990 • 23 citations

Release of elastase from purified human lung mast cells and basophils

1989 • 22 citations

Conclusions

1991 • 21 citations

Urticaria Pigmentosa with Bone Involvement

1963 • 21 citations

Endorphins in Infant Apnea

1982 • 21 citations

Cutaneous mastocytosis without clinically obvious skin lesions

1984 • 20 citations

AUTOGRAFTS IN PSORIASIS.

1965 • 18 citations

Systemic mastocytosis with diffuse crocodile-like pachydermic skin, pedunculated pseudofibromas and comedones

1980 • 17 citations

Secretory Diarrhea and Prostaglandin D₂Overproduction in Systemic Mastocytosis

1982 • 16 citations

Getting the Story Right

1993 • 14 citations

Xanthelasmoidea. An unusual case of urticaria pigmentosa

1976 • 13 citations

Atypical Diffuse Cutaneous Mastocytosis

1972 • 12 citations

Xanthelasmoidea

1976 • 12 citations

Solitary Mastocytoma

1969 • 9 citations

Mucopolysaccharides in Mast Cells and Mastocytosis**From the Department of Dermatology, Walter Reed Army Institute of Research, Washington, D.C.

1965 • 8 citations

Mast Cell Proteases

2003 • 6 citations

Histamine H₁ and H₂ Receptors

1984 • 2 citations

Deleted Work

1955 • 0 citations