New Insights into “The Riddle of the Mast Cells”: Microenvironmental Regulation of Mast Cell Development and Phenotypic Heterogeneity

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

Biology of the Laboratory Mouse

1967 • 1,382 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 • 1,199 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

Two types of human mast cells that have distinct neutral protease compositions.

1986 • 999 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors

1986 • 901 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 846 citations

Biology of the Laboratory Mouse

1941 • 826 citations

Establishment of an immature mast cell line from a patient with mast cell leukemia

1988 • 749 citations

Inflammatory Mediators in Late Antigen-Induced Rhinitis

1985 • 708 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

IL-4 is required to generate and sustain in vivo IgE responses.

1988 • 671 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 634 citations

Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of guinea pigs

1985 • 628 citations

B-Cell Stimulatory Factor-1/Interleukin 4

1987 • 602 citations

Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin

1985 • 592 citations

Mediator Release after Nasal Airway Challenge with Allergen

1986 • 568 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

The mast cells

1965 • 520 citations

Complete structure and expression in transfected cells of high affinity IgE receptor

1989 • 515 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation

1989 • 494 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Heterogeneity of Mast Cells and Phenotypic Change Between Subpopulations

1989 • 484 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity.

1983 • 465 citations

Flare and Itch Induced by Substance P in Human Skin

1978 • 460 citations

Native heparin from rat peritoneal mast cells.

1977 • 404 citations

The mast cell.

1981 • 399 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

COMPARISON OF WEIGHT REDUCTION WITH METOPROLOL IN TREATMENT OF HYPERTENSION IN YOUNG OVERWEIGHT PATIENTS

1985 • 370 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Blood. Principles and practice of hematology

1997 • 367 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Mast cells increase in tissues of neonatal rats injected with the nerve growth factor

1977 • 357 citations

B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells

1987 • 355 citations

Basophil counting with a new staining method using alcian blue

1975 • 351 citations

Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells

1981 • 349 citations

Mast cell differentiation and heterogeneity

1985 • 341 citations

Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism

1985 • 330 citations

Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins.

1988 • 327 citations

ELECTRON MICROSCOPE OBSERVATIONS ON COMPOUND 48/80-INDUCED DEGRANULATION IN RAT MAST CELLS

1971 • 319 citations

Human intestinal mucosal mast cells: evaluation of fixation and staining techniques.

1981 • 319 citations

Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice

1986 • 313 citations

Substance P regulates the vasodilator activity of calcitonin gene-related peptide

1988 • 306 citations

Basophil influx occurs after nasal antigen challenge: Effects of topical corticosteroid pretreatment

1988 • 305 citations

Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase.

1988 • 301 citations

Structure and Function of the Chemical Mediators of Mast Cells

2015 • 295 citations

Animal model of human disease.

1975 • 291 citations

Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells.

1982 • 291 citations

Coculture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells.

1986 • 287 citations

Absence of intestinal mast cell response in congenitally athymic mice during Trichinella spiralis infection

1976 • 284 citations

Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfate.

1982 • 282 citations

Studies on the mechanism of action of dantrolene sodium

1972 • 278 citations

Crohn's disease: Transmission electron microscopic studies

1980 • 276 citations

Human skin mast cells: their dispersion, purification, and secretory characterization.

1987 • 274 citations

Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells.

1987 • 268 citations

Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders.

1979 • 266 citations

Purification and characterization of human skin mast cells. Evidence for human mast cell heterogeneity.

1987 • 257 citations

Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor.

1987 • 245 citations

Basophils and Mast Cells: Morphologic Insights into Their Biology, Secretory Patterns, and Function1

2015 • 242 citations

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3.

1986 • 238 citations

Growth of a pure population of mouse mast cells in vitro with conditioned medium derived from concanavalin A-stimulated splenocytes.

1981 • 238 citations

Mucosal mast cells

1984 • 237 citations

Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells.

1983 • 228 citations

The reticuloendothelial system: A comprehensive treatise

1984 • 224 citations

Spleen colony-forming cell as common precursor for tissue mast cells and granulocytes

1981 • 224 citations

Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte function.

1987 • 223 citations

Mechanisms of Release of Biogenic Amines.

1967 • 222 citations

125I-fibrin deposition in IgE-dependent immediate hypersensitivity reactions in mouse skin. Demonstration of the role of mast cells using genetically mast cell-deficient mice locally reconstituted with cultured mast cells.

1987 • 214 citations

DIFFERENTIATION AND PROLIFERATION OF EMBRYONIC MAST CELLS OF THE RAT

1965 • 211 citations

Long-term in vitro culture of murine mast cells. I. Description of a growth factor-dependent culture technique.

1981 • 208 citations

Induction of human cutaneous mast cell degranulation by opiates and endogenous opioid peptides: Evidence for opiate and nonopiate receptor participation

1984 • 201 citations

PROTEOLYTIC ENZYMES OF MAST CELLS*

1963 • 197 citations

Substance P induces granulocyte infiltration through degranulation of mast cells.

1989 • 195 citations

Expression of High-affinity Binding of Human Immunoglobulin E by Transfected Cells

1989 • 194 citations

Substance P-induced augmentation of cutaneous vascular permeability and granulocyte infiltration in mice is mast cell dependent.

1989 • 186 citations

Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells.

1976 • 177 citations

A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3.

1985 • 174 citations

Mast cell clones: a model for the analysis of cellular maturation.

1982 • 174 citations

Ablation of immunity to Amblyomma americanum by anti-basophil serum: cooperation between basophils and eosinophils in expression of immunity to ectoparasites (ticks) in guinea pigs.

1982 • 170 citations

Development of human mast cells in vitro.

1989 • 165 citations

Bullous Pemphigoid, and Ultrastructural Study of the Inflammatory Response: Eosinophil, Basophil and Mast Cell Granule Changes in Multiple Biopsies from One Patient

1982 • 164 citations

Berberine sulphate binding to mast cell polyanions: A cytofluorometric method for the quantitation of heparin

1974 • 163 citations

Morphology Of Delayed-Type Hypersensitivity Reactions In Man

1976 • 161 citations

Ultrastructural analysis of human T and TC mast cells identified by immunoelectron microscopy.

1988 • 160 citations

Mast Cell and Basophil Differentiation and Function in Health and Disease

1989 • 159 citations

Interleukin 3: Possible Roles in the Regulation of Lymphocyte Differentiation and Growth

1982 • 157 citations

Immunofluorescent localization of a serine protease in rat small intestine.

1978 • 157 citations

Clonal assay of mouse mast cell colonies in methylcellulose culture

1982 • 155 citations

Continuous Lines of Basophil/Mast Cells Derived from Normal Mouse Bone Marrow

1981 • 154 citations

Heterogeneity of human mast cells.

1983 • 151 citations

THE IN VITRO DIFFERENTIATION OF MAST CELLS

1967 • 151 citations

Comparison of Histamine Release in Human Skin Mast Cells Induced by Morphine, Fentanyl, and Oxymorphone

1985 • 149 citations

Über die Zellformen des lockeren Bindegewebes

1905 • 147 citations

Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells.

1987 • 144 citations

Fibroblasts maintain the phenotype and viability of the rat heparin-containing mast cell in vitro.

1985 • 140 citations

Isolation and characterization of human intestinal mucosal mast cells.

1985 • 138 citations

Generation of mucosal mast cells is stimulated in vitro by factors derived from T cells of helminth-infected rats

1982 • 135 citations

Neurogenic inflammation, vascular permeability, and mast cells.

1988 • 132 citations

Preparative purification of the rat mast cell chymase. Characterization and Interaction with granule components

1977 • 131 citations

Human skin chymotryptic proteinase. Isolation and relation to cathepsin g and rat mast cell proteinase I.

1983 • 129 citations

Mast cell-dependent amplification of an immunologically nonspecific inflammatory response. Mast cells are required for the full expression of cutaneous acute inflammation induced by phorbol 12-myristate 13-acetate.

1988 • 127 citations

Fundamental immunology

1985 • 126 citations

Effects of sodium cromoglycate and nedocromil sodium on histamine secretion from human lung mast cells.

1988 • 124 citations

Unequivocal Delayed Hypersensitivity in Mast Cell-Deficient and Beige Mice

1984 • 121 citations

Mast cells in human keloid, small intestine, and lung by an immunoperoxidase technique using a murine monoclonal antibody against tryptase.

1986 • 121 citations

Phagocytosis of mast cell granules by cultured fibroblasts.

1983 • 119 citations

In in vitro production and cloning of the P cell, a bone marrow-derived null cell that expresses H-2 and Ia-antigens, has mast cell-like granules, and is regulated by a factor released by activated T cells.

1981 • 118 citations

Mouse bone marrow-derived mast cells cocultured with fibroblasts. Morphology and stimulation-induced release of histamine, leukotriene B4, leukotriene C4, and prostaglandin D2.

1987 • 116 citations

Development of rat mast cells in vitro. I. Differentiation of mast cells from thymus cells.

1976 • 116 citations

Contributions of Electron Microscopy to the Study of Mast Cells

1972 • 114 citations

Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.

1988 • 113 citations

Metabolically inactive 3T3 cells can substitute for marrow stromal cells to promote the proliferation and development of multipotent haemopoietic stem cells

1987 • 110 citations

Inhibition of basophil histamine release by anti-inflammatory steroids. II. Studies on the mechanism of action.

1982 • 109 citations

New role for 15-hydroxyeicosatetraenoic acid. Activator of leukotriene biosynthesis in PT-18 mast/basophil cells.

1982 • 109 citations

A major serine protease in rat skeletal muscle: Evidence for its mast cell origin

1978 • 107 citations

Ultrastructural identification of the mouse basophil

1982 • 106 citations

IL-3-dependent growth of basophil-like cells and mastlike cells from human bone marrow.

1989 • 106 citations

Complexes of heparin proteoglycans, chondroitin sulfate E proteoglycans, and [3H]diisopropyl fluorophosphate-binding proteins are exocytosed from activated mouse bone marrow-derived mast cells.

1986 • 106 citations

Mast Cell Heterogeneity in Man

1985 • 103 citations

Specificity of a mouse monoclonal antibody raised against acute myeloid leukaemia cells for mast cells in human mucosal and connective tissues

1987 • 98 citations

Allergy: Principles and Practice

1989 • 98 citations

Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice.

1989 • 98 citations

Phenotypic changes of bone marrow-derived mast cells after intraperitoneal transfer into W/Wv mice that are genetically deficient in mast cells.

1987 • 97 citations

Co-culture of human lung-derived mast cells with mouse 3T3 fibroblasts: morphology and IgE-mediated release of histamine, prostaglandin D2, and leukotrienes.

1987 • 96 citations

Suspension culture of human mast cells/basophils from umbilical cord blood mononuclear cells.

1983 • 95 citations

Structure, specificity and localization of the serine proteases of connective tissue

1980 • 95 citations

Thiol-sensitive mast cell lines derived from mouse bone marrow respond to a mast cell growth-enhancing activity different from both IL-3 and IL-4.

1989 • 93 citations

Morphologic and immunologic characterization of human basophils developed in cultures of cord blood mononuclear cells.

1985 • 91 citations

Extensive proliferation of mature connective-tissue type mast cells in vitro

1986 • 91 citations

3T3 fibroblasts induce cloned interleukin 3-dependent mouse mast cells to resemble connective tissue mast cells in granular constituency.

1988 • 89 citations

Development of mucosal mast cells after injection of a single connective tissue-type mast cell in the stomach mucosa of genetically mast cell-deficient W/Wv mice.

1986 • 87 citations

Effect of p-nitrophenyl-beta-D-xyloside on proteoglycan and glycosaminoglycan biosynthesis in rat serosal mast cell cultures.

1982 • 86 citations

Ultrastructural analysis of maturing human T and TC mast cells in situ.

1989 • 86 citations

Formation of mast cell colonies in methylcellulose by mouse peritoneal cells and differentiation of these cloned cells in both the skin and the gastric mucosa of W/Wv mice: evidence that a common precursor can give rise to both "connective tissue-type" and "mucosal" mast cells.

1986 • 85 citations

Worm expulsion and mucosal mast cell response induced by repetitive IL-3 administration in Strongyloides ratti-infected nude mice.

1988 • 82 citations

Ultrastructural, biochemical, and functional characteristics of histamine-containing cells cloned from mouse bone marrow: tentative identification as mucosal mast cells.

1983 • 82 citations

Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation.

1984 • 81 citations

Fibroblast‐dependent growth of mouse mast cells in vitro: Duplication of mast cell depletion in mutant mice of w/w^v genotype

1988 • 81 citations

In vitro duplication and in vivo cure of mast-cell deficiency of Sl/Sld mutant mice by cloned 3T3 fibroblasts.

1989 • 80 citations

Basophil and mast cell degranulation: ultrastructural analysis of mechanisms of mediator release.

1983 • 76 citations

Does heparin occur in mucosal mast cells of the rat small intestine?

1977 • 76 citations

Immunoglobulin E-mediated degranulation of isolated human lung mast cells.

1985 • 74 citations

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

1988 • 71 citations

Growth and differentiation in vitro of mast cells from mesenteric lymph nodes of Nippostrongylus brasiliensis-infected rats.

1980 • 71 citations

Mast cells in severely T-cell depleted rats and the response to infestation with Nippostrongylus brasiliensis.

1979 • 70 citations

Anaphylaxis in Mast Cell-Deficient Mice

1984 • 70 citations

Factor-dependent in vitro growth of human normal bone marrow-derived basophil-like cells.

1983 • 69 citations

Mucosal mast cells in vivo and in vitro

1984 • 67 citations

Development of Rat Mast Cells in Vitro

1976 • 66 citations

A monoclonal antibody reacting with human basophils

1987 • 65 citations

Electron Microscopic Study of Human Basophils

1967 • 64 citations

Differentiation and activity of mast cells following immunization in cultures of lymph-node cells.

1978 • 64 citations

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

1988 • 64 citations

The Human Blood Basophil

1976 • 63 citations

Functional Characteristics of Mucosal and Connective Tissue Mast Cells of Man, the Rat and Other Animals

1985 • 61 citations

The isolation of heparin from mast cells of the normal rat

1959 • 61 citations

The role of mast cells in thioglycollate-induced inflammation.

1988 • 61 citations

Abnormal mast cell granules in the beige (Chédiak-Higashi syndrome) mouse.

1975 • 60 citations

THE RIDDLE OF THE MAST CELLS A TRIBUTE TO PAUL EHRLICH

1954 • 60 citations

Regulation of the growth rate of mouse fibroblasts by IL-3-activated mouse bone marrow-derived mast cells.

1989 • 59 citations

Immortalization of murine connective tissue-type mast cells at multiple stages of their differentiation by coculture of splenocytes with fibroblasts that produce Kirsten sarcoma virus.

1988 • 59 citations

Periodic, multimodal distribution of granule volumes in mast cells

1983 • 59 citations

A NEW SYNDROME CHARACTERISED BY ABSENCE OF EOSINOPHILS AND BASOPHILS

1977 • 57 citations

Effect of Fixation on the Light Microscopical Visualization of Mast Cells in the Mucosa and Connective Tissue of the Human Duodenum

1982 • 57 citations

Vesicular uptake of eosinophil peroxidase by guinea pig basophils and by cloned mouse mast cells and granule-containing lymphoid cells.

1985 • 55 citations

Long-term in vitro culture of murine mast cells. III. Discrimination of mast cells growth factor and granulocyte-CSF.

1982 • 55 citations

Mast cell heterogeneity: Evidence and implications

1984 • 55 citations

Human mast cells synthesize new granules during recovery from degranulation. In vitro studies with mast cells purified from human lungs

1988 • 55 citations

THE IN VITRO DIFFERENTIATION AND CULTURE OF NORMAL MAST CELLS FROM THE MOUSE THYMUS*

1963 • 54 citations

A hemopoietic cell line dependent upon a factor in pokeweed mitogen‐stimulated spleen cell conditioning medium

1980 • 53 citations

New approaches for the analysis of mast cell maturation, heterogeneity, and function.

1987 • 52 citations

Development of large numbers of mast cells at sites of idiopathic chronic dermatitis in genetically mast cell-deficient WBB6F1-W/Wv mice

1987 • 52 citations

Characterization of human mast cells in long-term culture

1983 • 51 citations

Production of BSF-1 during an in vivo, T-dependent immune response.

1986 • 51 citations

A New Look at Basophils in Mice

1981 • 51 citations

Decrease of mast cells in W/W[v] mice and their increase by bone marrow transplantation

1979 • 51 citations

The mast cell-committed progenitor. I. Description of a cell capable of IL-3-independent proliferation and differentiation without contact with fibroblasts.

1989 • 50 citations

Mast cell growth on fibroblast monolayers: two-cell entities.

1982 • 50 citations

Development of mast cells in vitro. II. Biologic function of cultured mast cells.

1977 • 49 citations

Inhibition of the growth of IL-3-dependent mast cells from murine bone marrow by recombinant granulocyte macrophage-colony-stimulating factor.

1989 • 48 citations

Separation of mast cells in successive stages of differentiation using programmed gradient sedimentation.

1970 • 48 citations

Two classes of mouse mast cells delineated by monoclonal antibodies.

1983 • 47 citations

Granule-associated serine neutral proteases of the mouse bone marrow-derived mast cell that degrade fibronectin: their increase after sodium butyrate treatment of the cells.

1984 • 47 citations

Infection of immune mast cells by Harvey sarcoma virus: immortalization without loss of requirement for interleukin-3.

1985 • 46 citations

Proliferation and differentiation in culture of mast cell progenitors derived from mast cell‐deficient mice of genotype W/W^v

1985 • 46 citations

CULTURE OF HUMAN MARROW

1937 • 45 citations

Biochemical and phenotypic characterization of human basophilic cells derived from dispersed fetal liver with murine T cell factors.

1986 • 44 citations

Ultrastructural criteria for identification of mast cells and basophils in humans, guinea pigs, and mice.

1983 • 44 citations

Reevaluation of reserpine-induced suppression of contact sensitivity. Evidence that reserpine interferes with T lymphocyte function independently of an effect on mast cells.

1985 • 42 citations

Differences in the volume distributions of human lung mast cell granules and lipid bodies: evidence that the size of these organelles is regulated by distinct mechanisms.

1985 • 42 citations

Ultrastructure of human basophils developing in vitro. Evidence for the acquisition of peroxidase by basophils and for different effects of human and murine growth factors on human basophil and eosinophil maturation.

1985 • 39 citations

The presence of mast cell precursors in rat peripheral blood

1981 • 39 citations

Changes in numbers and types of mast cell colony-forming cells in the peritoneal cavity of mice after injection of distilled water: evidence that mast cells suppress differentiation of bone marrow-derived precursors

1988 • 38 citations

Normalization of Anti-Tick Response of Mast Cell-Deficient W/W v Mice by Intracutaneous Injection of Cultured Mast Cells

1987 • 37 citations

The Wandering Cells of the Alimentary Canal

1895 • 37 citations

Partial purification of a mast cell growth-enhancing activity and its separation from IL-3 and IL-4.

1989 • 37 citations

Ethanol-induced acute gastric injury in mast cell-deficient and congenic normal mice. Evidence that mast cells can augment the area of damage.

1987 • 36 citations

Mouse heparin proteoglycan. Synthesis by mast cell-fibroblast monolayers during lymphocyte-dependent mast cell proliferation.

1982 • 36 citations

Defective cytoplasmic granule formation. I. Abnormalities affecting tissue mast cells and pancreatic acinar cells of beige mice.

1987 • 34 citations

Failure of W/Wv mouse-derived cultured mast cells to enter S phase upon contact with NIH/3T3 fibroblasts

1988 • 34 citations

Development of large numbers of mast cells at sites of idiopathic chronic dermatitis in genetically mast cell-deficient WBB6F1-W/Wv mice

1987 • 34 citations

Selective growth of a population of human basophil cells in vitro.

1981 • 32 citations

Phenotypic changes in mast cells proliferating in the rat lung following infection withNippostrongylus brasiliensis

1987 • 31 citations

Bone Marrow Origin of Mucosal Mast Cells

1984 • 31 citations

Histochemical heterogeneity of dermal mast cells in athymic and normal rats

1988 • 30 citations

Effect of cycloheximide, β-<scp>d</scp>-xylosides and β-<scp>d</scp>-galactosides on heparin biosynthesis in mouse mastocytoma

1981 • 30 citations

Induction of Intestinal Mastocytosis in Nude Mice by Repeated Injection of Interleukin-3

1988 • 30 citations

The mast cell-committed progenitor. II. W/Wv mice do not make mast cell-committed progenitors and S1/S1d fibroblasts do not support development of normal mast cell-committed progenitors.

1989 • 29 citations

Thymus Dependence of Connective Tissue Mast Cells: A Quantitative Cytofluorometric Study of the Growth of Peritoneal Mast Cells in Normal and Athymic Rats

1985 • 29 citations

Effect of sodium butyrate on the production of serotonin, histamine and glycosaminoglycans by cultured murine mastocytoma cells

1980 • 29 citations

Studies on the growth of mast cells in rats. Changes in granule size between 1 and 6 months.

1988 • 28 citations

Studies of the role of mast cells in contact sensitivity responses

1987 • 27 citations

Mast cell restoration. A study of the rat peritoneal mast cells after depletion with polymyxin B.

1981 • 25 citations

Establishment of four mouse mastocytoma cell lines

1985 • 24 citations

Basophil Leukocyte Differential in Blood and Bone Marrow

1963 • 23 citations

Cloned Mouse Mast Cells and Normal Mouse Peritoneal Mast Cells

1985 • 23 citations

Coculture of mouse IL-3-dependent mast cells with 3T3 fibroblasts stimulates synthesis of globopentaosylceramide (Forssman glycolipid) by fibroblasts and surface expression on both populations.

1988 • 22 citations

Enhancement of Mast Cell Differentiation in vitro by T Cell Factor(s)

1981 • 22 citations

Genetically mast cell-deficient W/Wv mice as a tool for studies of differentiation and function of mast cells.

1987 • 21 citations

Development of Mast Cells in Vitro

1977 • 21 citations

Analysis of pure and mixed murine mast cell colonies

1984 • 19 citations

STRUCTURAL ASPECTS OF HISTAMINE BINDING: THE MAST CELL GRANULE**Supported in part by a grant-in-aid from the United States Public Health Service (HE-03174).

1966 • 19 citations

Identification and characterization of human hemopoietic mast cell colonies.

1988 • 19 citations

Functional and biochemical characterization of rat bone marrow derived mast cells.

1988 • 19 citations

Mast Cell Restoration

1981 • 17 citations

Mast cell granule proteases in mouse and rat: A guide to mast cell heterogeneity and activation in the gastrointestinal tract

1989 • 17 citations

Mast cell-mediated toxicity to schistosomula of Schistosoma mansoni: potentiation by exogenous peroxidase.

1986 • 16 citations

Ontogeny of in vitro-differentiated mouse mast cells.

1987 • 16 citations

Immunogold probe for the light-microscopic phenotyping of human mast cells and basophils

1987 • 15 citations

An inherited anomaly of human eosinophils and basophils.

1978 • 15 citations

Biochemical and morphological modifications in dexamethasone-treated mouse bone marrow-derived mast cells.

1988 • 14 citations

Peroxidase Activity in Circulating Mast Cells in Blast Crisis of Chronic Granulocytic Leukemia: Comparative Studies with Basophils and Cutaneous Mast Cells

1986 • 13 citations

Coincident basophilic chronic myelogenous leukemia and pulmonary tuberculosis. Associated with extreme elevations of blood histamine levels and maturity onset asthma

1968 • 12 citations

Cultured human bone marrow-derived mast cells, their similarities to cultured murine E-mast cells.

1988 • 11 citations

Basophils and Mast Cells: Morphologic Insights into Their Biology, Secretory Patterns, and Function (Part 1 of 7)

1984 • 9 citations

Cutaneous Basophil Hypersensitivity

1986 • 9 citations

Medium Conditioned by Spleen Cells of &lt;i&gt;Nematospiroides dubiu&lt;/i&gt;&lt;i&gt;s&lt;/i&gt;-lnfected Mice Does Not Support Development of Cultured Mast Cells

1988 • 8 citations

Cell membrane glycoproteins of human mast cells: a biochemical comparison with basophils.

1986 • 7 citations

Basophil and eosinophil deficiency in a patient with hypogammaglobulinemia associated with thymoma.

1983 • 7 citations

Further Biochemical Characterization of Human Basophil-Like Cell-Promoting Activity and Its Distinction from Human Interleukin-3-Like Activity

1988 • 7 citations

Ultrastructure of the mouse blood basophil.

1983 • 6 citations

Mast Cell Differentiation in Cultures of T Cell-Depleted Mesenteric Lymph Node Cells from &lt;i&gt;Nippostrongylus brasiliensi&lt;/i&gt;&lt;i&gt;s&lt;/i&gt;-lnfected Mice

1988 • 6 citations

Human Mast Cells

1989 • 6 citations

The Innervation of Mast Cells

2018 • 5 citations

Immediate hypersensitivity

1975 • 5 citations

Prostaglandin D2 generation in mouse bone marrow-derived mast cells exposed to dexamethasone is associated with endogenous peroxidase activity.

1988 • 5 citations

Mast cell growth factor.

1983 • 4 citations

Studies on kinetics of human leucocytes in vivo with 3H-thymidine autoradiography. II. Eosinophils and basophils.

1969 • 2 citations