Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor.

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 • 1,199 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Mast cells as a source of multifunctional cytokines

1990 • 708 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

New Insights into “The Riddle of the Mast Cells”: Microenvironmental Regulation of Mast Cell Development and Phenotypic Heterogeneity

1990 • 625 citations

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

1990 • 599 citations

Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines.

1989 • 557 citations

Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit

1990 • 521 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation

1989 • 494 citations

Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors.

1990 • 304 citations

Coculture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells.

1986 • 287 citations

Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfate.

1982 • 282 citations

Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells.

1987 • 268 citations

Mast cell clones: a model for the analysis of cellular maturation.

1982 • 174 citations

Berberine sulphate binding to mast cell polyanions: A cytofluorometric method for the quantitation of heparin

1974 • 163 citations

Mast Cell and Basophil Differentiation and Function in Health and Disease

1989 • 159 citations

Extensive proliferation of mature connective-tissue type mast cells in vitro

1986 • 91 citations

Ultrastructural, biochemical, and functional characteristics of histamine-containing cells cloned from mouse bone marrow: tentative identification as mucosal mast cells.

1983 • 82 citations

In vitro duplication and in vivo cure of mast-cell deficiency of Sl/Sld mutant mice by cloned 3T3 fibroblasts.

1989 • 80 citations

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

1988 • 71 citations

Identification of chondroitin sulfate E in human lung mast cells.

1988 • 71 citations

Development of large numbers of mast cells at sites of idiopathic chronic dermatitis in genetically mast cell-deficient WBB6F1-W/Wv mice

1987 • 52 citations

Phorbol 12-myristate 13-acetate-induced development of functionally active mast cells in W/Wv but not Sl/Sld genetically mast cell- deficient mice

1990 • 41 citations

Mouse heparin proteoglycan. Synthesis by mast cell-fibroblast monolayers during lymphocyte-dependent mast cell proliferation.

1982 • 36 citations

Mast Cells: Immunologically Specific Effectors and Potential Sources of Multiple Cytokines During IgE‐Dependent Responses

2007 • 34 citations

IgE, Mast Cells and the Allergic Response

1990 • 22 citations

IgE, mast cells, and the allergic response

1989 • 15 citations