The Diversity Of Mast Cell-Derived Mediators: Implications For Acute, Subacute, And Chronic Cutaneous Inflammatory Disorders

Definition and Antagonism of Histamine H2-receptors

1972 • 2,284 citations

STUDIES ON INFLAMMATION

1961 • 714 citations

The release of histamine and formation of a slow‐reacting substance (SRS‐A) during anaphylactic shock

1960 • 638 citations

Disodium Cromoglycate (FPL 670) (‘Intal’*): a Specific Inhibitor of Reaginic Antibody–Antigen Mechanisms

1967 • 440 citations

Cold Urticaria: Release into the Circulation of Histamine and Eosinophil Chemotactic Factor of Anaphylaxis during Cold Challenge

1976 • 390 citations

Eosinophils as mediators of antibody-dependent damage to schistosomula

1975 • 369 citations

Dermatology in General Medicine

1971 • 365 citations

Modification of the enzymatic isotopic assay of histamine and its application to measurement of histamine in tissues, serum and urine

1972 • 345 citations

IMMUNOLOGICAL RELEASE OF HISTAMINE AND SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS FROM HUMAN LUNG

1971 • 338 citations

Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils

1974 • 279 citations

AN EOSINOPHIL LEUKOCYTE CHEMOTACTIC FACTOR OF ANAPHYLAXIS

1971 • 266 citations

In vivo studies of mediator release in cold urticaria and cholinergic urticaria

1975 • 247 citations

The IgE-Mediated Release of an Eosinophil Leukocyte Chemotactic Factor from Human Lung

1971 • 244 citations

Morphology of delayed type hypersensitivity reactions in man. I. Quantitative description of the inflammatory response.

1974 • 241 citations

The effects of the H1 and H2 antihistamines on "allergic" histamine release and its inhibition by histamine.

1975 • 233 citations

Slow Reacting Substance of Anaphylaxis

1969 • 230 citations

REACTIONS OF ISOLATED HUMAN ASTHMATIC LUNG AND BRONCHIAL TISSUE TO A SPECIFIC ANTIGEN HISTAMINE RELEASE AND MUSCULAR CONTRACTION

1951 • 222 citations

PREVENTION OF ENDEMIC GOITRE

1965 • 221 citations

Purification and synthesis of eosinophilotactic tetrapeptides of human lung tissue: identification as eosinophil chemotactic factor of anaphylaxis.

1975 • 217 citations

FORMATION OF C3a AND C5a ANAPHYLATOXINS IN WHOLE HUMAN SERUM AFTER INHIBITION OF THE ANAPHYLATOXIN INACTIVATOR

1973 • 204 citations

PROTEOLYTIC ENZYMES OF MAST CELLS*

1963 • 197 citations

Inactivation of Slow Reacting Substance of Anaphylaxis by Human Eosinophil Arylsulfatase

1975 • 189 citations

Histamine release from human leukocytes: studies with deuterium oxide, colchicine, and cytochalasin B

1972 • 182 citations

RELEASE OF VASOACTIVE AMINES FROM RABBIT PLATELETS INDUCED BY SENSITIZED MONONUCLEAR LEUKOCYTES AND ANTIGEN

1970 • 170 citations

Immunologic release of histamine and slow reacting substance of anaphylaxis from human lung. V. Effects of prostaglandins on release of histamine.

1973 • 168 citations

The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis.

1973 • 167 citations

Properties of a subpopulation of T cells bearing histamine receptors.

1975 • 160 citations

Immunologic Release of Chemical Mediators from Human Nasal Polyps

1973 • 158 citations

MATURATION OF RAT MAST CELLS

1966 • 151 citations

The Physicochemical Characteristics and Purification of Slow-Reacting Substance of Anaphylaxis

1973 • 146 citations

Pharmacologic Inhibition of the Antigen-Induced Release of Histamine and Slow Reacting Substance of Anaphylaxis (SRS-A) from Monkey Lung Tissues Mediated by Human IgE

1971 • 141 citations

Isolation of human eosinophil phospholipase D.

1976 • 139 citations

Itch: Role of Prostaglandins

1973 • 135 citations

Mast Cell Population in Human Skin**From the Department of Dermatology, Wayne State University College of Medicine and Detroit Receiving Hospital, Detroit, Michigan.

1964 • 128 citations

Prostaglandins

1972 • 118 citations

Histologic studies of human skin test responses to ragweed, compound 48/80, and histamine

1973 • 117 citations

Contributions of Electron Microscopy to the Study of Mast Cells

1972 • 114 citations

Inhibition of Allergic Reactions in Man and Other Species by Cromoglycate

1970 • 113 citations

Gross and ultrastructural observations on lesions produced by intradermal injection of human C3a in man.

1970 • 111 citations

The release of four mediators of immediate hypersensitivity from human leukemic basophils.

1975 • 111 citations

Inactivation of slow reacting substance of anaphylaxins (SRS-A) by arylsulfatases.

1974 • 109 citations

THE HISTAMINE-LIKE ACTION OF CURANE AND TUBOCURARINE INJECTED INTRACUTANEOUSLY AND INTRA-ARTERIALLY IN MAN

1946 • 96 citations

The Release of Four Mediators of Immediate Hypersensitivity from Human Leukemic Basophils

1975 • 96 citations

Inactivation of Slow Reacting Substance of Anaphylaxis (SRS-A) by Arylsulfatases

1974 • 95 citations

Cutaneous responses to human C 3 anaphylatoxin in man.

1972 • 92 citations

Effect of Histamine and Its Methyl Derivatives on Cyclic AMP Metabolism in Gastric Mucosa and Its Blockade by an H2 Receptor Antagonist

1974 • 91 citations

Dermographia mediated by immunoglobulin E

1973 • 89 citations

FORMATION OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS IN HUMAN LUNG TISSUE AND CELLS BEFORE RELEASE

1974 • 89 citations

Chemotaxis of Basophils by Lymphocyte-Dependent and Lymphocyte-Independent Mechanisms

1975 • 88 citations

Selective attraction of eosinophils and synergism between eosinophil chemotactic factor of anaphylaxis (ECF-A) and a fragment cleaved from the fifth component of complement (C5a).

1973 • 88 citations

Atropine modification of the pulmonary effects of chemical mediators in the guinea pig

1975 • 88 citations

Effects of Bradykinin and Indomethacin on Cyclic GMP and Cyclic AMP in Lung Slices

1973 • 84 citations

Immunochemical and biologic properties of rat IgE. II. Capacity to mediate the immunologic releas of histamine an slow-reacting substance of anaphylaxis (SRS-A).

1970 • 84 citations

Role of Mast Cell and Basophil in Cold Urticaria with Associated Systemic Reactions

1961 • 81 citations

Blockade by burimamide of the effects of histamine and histamine analogs on cardiac contractility, phosphorylase activation and cyclic adenosine monophosphate.

1974 • 77 citations

The fine structure of connective tissue

1962 • 76 citations

Ultrastructure of human mast-cell granules

1968 • 75 citations

Disodium Cromoglycate

1970 • 74 citations

Disodium cromoglycate. Activity in three in vitro models of the immediate hypersensitivity reaction in lung.

1970 • 71 citations

Pharmacology and Pharmacokinetics

1974 • 70 citations

Chemotaxis of human basophil leucocytes.

1972 • 58 citations

Biologic properties of rat antibodies. II. Time-course of appearance of antibodies involved in antigen-induced release of slow reacting substance of anaphylaxis (SRS-A rat); association of this activity with rat IgGa.

1968 • 55 citations

The mast cell in health and disease

1993 • 52 citations

Arylsulfatase B of human lung. Isolation, characterization, and interaction with slow-reacting substance of anaphylaxis.

1976 • 52 citations

Immunochemical and Biologic Properties of Rat IgE

1970 • 51 citations

Cutaneous Thermography with Liquid Crystals*†

1965 • 50 citations

A fine structure study of some cellular components in allergic reactions

1974 • 48 citations

An Electron Microscopic Study of the Degranulation of Mast Cell Granules in Urticaria Pigmentosa*

1966 • 47 citations

Clinical Presentations And Mechanisms Of Necrotizing Angiitis Of The Skin

1976 • 47 citations

Plasma histamine concentrations in allergic diseases

1963 • 45 citations

Histamine, hormones, and hypersensitivity

1954 • 45 citations

Activation and control mechanisms of Hageman factor-dependent pathways of coagulation, fibrinolysis, and kinin generation and their contribution to the inflammatory response

1975 • 42 citations

Chemotactic Deactivation of Human Eosinophils by the Eosinophil Chemotactic Factor of Anaphylaxis

1975 • 41 citations

Release of Slow Reacting Substance of Anaphylaxis from Human Leukocytes

1974 • 40 citations

Degranulation and regranulation of human mast cells. An electron microscopic study of the whealing reaction in urticaria pigmentosa.

1969 • 39 citations

N-Acetyl-β-glucosaminidase in rat mast cell granules

1970 • 37 citations

Destruction of rabbit platelets in the allergic response of sensitized leukocytes. II. Evidence for basophil involvement.

1971 • 35 citations

The fine structure of connective tissue

1963 • 34 citations

IgE-mediated hypersensitivity in human skin studied using a new in vitro method.

1972 • 32 citations

Cyclic AMP-induced inhibition of IgE-mediated hypersensitivity in human skin.

1973 • 32 citations

Effect of disodium cromoglycate on antigen-evoked histamine release from human skin.

1974 • 30 citations

Dissociation of the Immunologic Release of Histamine and Slow Reacting Substance of Anaphylaxis from Human Lung Using Cytochalasins A and B

1975 • 30 citations

PROCEEDINGS OF THE British Pharmacological Society

1974 • 25 citations

Increased blood histamine in thermal intolerance

1958 • 23 citations

Mastocytoma Cell Migration in Vitro: Inhibition by MIF-Containing Supernatants

1975 • 21 citations

Regulation of Gingival Collagenase: A Possible Role for a Mast Cell Factor

1974 • 21 citations

Electron microscopic studies of mast cell degranulation.

1973 • 16 citations

Inhibition of Immediate Hypersensitivity Reactions in the Rat by ICI 74, 917 and Disodium Cromoglycate

1975 • 15 citations

Probable Role of Prostaglandins in Asthma

1975 • 15 citations

Fluid Therapy in Severe Systemic Reaction to Radiopaque Dye

1975 • 14 citations

Combined biochemical and morphological ultrastructure studies on mast-cell granules.

1967 • 10 citations

Diffuse Urticaria Pigmentosa: An Ultrastructural Study Before And After Whealing

1967 • 10 citations

Inhibition of human cutaneous anaphylaxis by cytochalasin B.

1973 • 8 citations

Passive sensitization of guinea-pig skin in vitro for the antigen-induced release of anaphylactic mediators.

1974 • 7 citations

The Leukocytic Response to Aseptic Inflammation in Urticaria Pigmentosa*

1965 • 7 citations