Tryptase Levels as an Indicator of Mast-Cell Activation in Systemic Anaphylaxis and Mastocytosis

Two types of human mast cells that have distinct neutral protease compositions.

1986 • 999 citations

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

1982 • 588 citations

Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells.

1987 • 504 citations

Release of Prostaglandin D₂into Human Airways during Acute Antigen Challenge

1986 • 476 citations

Increased Production of Prostaglandin D2 in Patients with Systemic Mastocytosis

1980 • 430 citations

Tryptase from human pulmonary mast cells. Purification and characterization.

1981 • 428 citations

The mast cell.

1981 • 399 citations

Physiologic manifestations of human anaphylaxis.

1980 • 385 citations

Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer.

1986 • 348 citations

Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells.

1981 • 332 citations

Increased sensitivity of the enzymatic isotopic assay of histamine: Measurement of histamine in plasma and serum

1979 • 321 citations

Evaluation of human peripheral blood leukocytes for mast cell tryptase.

1987 • 281 citations

Arachidonic acid metabolism in purified human lung mast cells.

1984 • 234 citations

Diagnosis, prevention, and treatment of adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs

1984 • 216 citations

Improved Diagnosis of Mastocytosis by Measurement of Urinary Hist Amine Metabolites

1983 • 175 citations

Human lung tryptase. Purification and characterization.

1984 • 172 citations

Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release.

1984 • 168 citations

Biosynthesis of prostaglandin D2 1. Formation of prostaglandin D2 by human platelets

1977 • 140 citations

Synthesis of leukotriene B4, and prostanoids by human alveolar macrophages: analysis by gas chromatography/ mass spectrometry

1984 • 130 citations

Mast cells in human keloid, small intestine, and lung by an immunoperoxidase technique using a murine monoclonal antibody against tryptase.

1986 • 121 citations

Exercise-induced anaphylaxis: a distinct form of physical allergy.

1983 • 118 citations

Monoclonal antibodies against human mast cell tryptase demonstrate shared antigenic sites on subunits of tryptase and selective localization of the enzyme to mast cells.

1985 • 118 citations

Comparison of the therapeutic efficacy of cromolyn sodium with that of combined chlorpheniramine and cimetidine in systemic mastocytosis. Results of a double-blind clinical trial

1985 • 109 citations

Plasma kallikrein during experimentally induced allergic rhinitis: role in kinin formation and contribution to TAME-esterase activity in nasal secretions.

1986 • 105 citations

Immunoassay of tryptase from human mast cells

1986 • 80 citations

Aspirin-Sensitive Asthma: Abnormal Platelet Response to Drugs Inducing Asthmatic Attacks

1985 • 77 citations

Measurement of urinary histamine: Development of methodology and normal values

1981 • 56 citations

Patterns of skeletal scintigraphy and their relationship to plasma and urinary histamine levels in systemic mastocytosis.

1984 • 51 citations

Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: Relevance of circulating basophils to measurements of plasma histamine

1984 • 51 citations

Measurement ofN τ-methylhistamine concentrations in plasma and urine as a parameter for histamine release during anaphylactoid reactions

1985 • 43 citations

Increased Urine Histamine and Contrast Media Reactions

1984 • 35 citations

Localization of tryptase to human cutaneous mast cells and keratinocytes by immunofluorescence and immunoperoxidase cytochemistry with monoclonal antitryptase antibody

1985 • 34 citations

Histaminuria From Histamine-Rich Foods

1983 • 29 citations

Failure of sulfites to produce clinical responses in patients with systemic mastocytosis or recurrent anaphylaxis: Results of a single-blind study

1985 • 27 citations

Investigation of the Possible Involvement of IgE Anti-Salicyloyl Antibodies in Patients with Urticaria

1981 • 18 citations

Analysis of plasma histamine: A modification of the enzymatic isotopic assay

1986 • 15 citations