Specificity and detection of insulin-reactive CD4+T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse

Use of Peptide Libraries to Map the Substrate Specificity of a Peptide-Modifying Enzyme: A 13 Residue Consensus Peptide Specifies Biotinylation in Escherichia coli

1993 • 586 citations

Detection of Antigen-Specific T Cells with Multivalent Soluble Class II MHC Covalent Peptide Complexes

1998 • 465 citations

Peptide ‘Velcro’: Design of a heterodimeric coiled coil

1993 • 437 citations

Epitope specificity, cytokine production profile and diabetogenic activity of insulin‐specific T cell clones isolated from NOD mice

1995 • 359 citations

Chromogranin A is an autoantigen in type 1 diabetes

2010 • 330 citations

How the T Cell Repertoire Becomes Peptide and MHC Specific

2005 • 310 citations

Production of soluble MHC class II proteins with covalently bound single peptides

1994 • 302 citations

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

2008 • 265 citations

A Structural Framework for Deciphering the Link Between I-A ^g7 and Autoimmune Diabetes

2000 • 256 citations

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders.

1996 • 217 citations

Structural Basis of Peptide Binding and Presentation by the Type I Diabetes-Associated MHC Class II Molecule of NOD Mice

2000 • 197 citations

Insulin as an autoantigen in NOD/human diabetes

2008 • 193 citations

Diabetogenic T cells recognize insulin bound to IA^g7in an unexpected, weakly binding register

2010 • 189 citations

T-Lymphocyte Clone Specific for Pancreatic Islet Antigen

1988 • 188 citations

Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

2005 • 181 citations

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

2010 • 174 citations

T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage

1997 • 174 citations

A comprehensive guide to antibody and T‐cell responses in type 1 diabetes

2003 • 166 citations

Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis

2009 • 116 citations

Crystal structure of HLA-DP2 and implications for chronic beryllium disease

2010 • 115 citations

Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue

2001 • 108 citations

The Insulin-Specific T Cells of Nonobese Diabetic Mice Recognize a Weak MHC-Binding Segment in More Than One Form

2007 • 100 citations

T cell receptor restriction of diabetogenic autoimmune NOD T cells

1997 • 99 citations

Structural Snapshot of Aberrant Antigen Presentation Linked to Autoimmunity

2002 • 98 citations

On the Pathogenicity of Autoantigen-Specific T-Cell Receptors

2008 • 95 citations

Anti-LFA-1 Therapy Induces Long-Term Islet Allograft Acceptance in the Absence of IFN-γ or IL-4

2000 • 90 citations

The role of HLA-DQ8 β57 polymorphism in the anti-gluten T-cell response in coeliac disease

2008 • 88 citations

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

2011 • 84 citations

In APCs, the Autologous Peptides Selected by the Diabetogenic I-Ag7 Molecule Are Unique and Determined by the Amino Acid Changes in the P9 Pocket

2002 • 76 citations

Mimotopes for Alloreactive and Conventional T Cells in a Peptide–MHC Display Library

2004 • 74 citations

Minute quantities of a single immunodominant foreign epitope are presented as large nested sets by major histocompatibility complex class II molecules

1993 • 73 citations

Use of baculovirus MHC/peptide display libraries to characterize T‐cell receptor ligands

2006 • 73 citations

The post-translational processing of chromogranin A in the pancreatic islet: involvement of the eukaryote subtilisin PC2

1994 • 69 citations

Dual Overlapping Peptides Recognized by Insulin Peptide B:9–23 T Cell Receptor AV13S3 T Cell Clones of the NOD Mouse

2000 • 63 citations

Detection and Characterization of T Cells Specific for BDC2.5 T Cell-Stimulating Peptides

2003 • 56 citations

Ex Vivo Analysis of Thymic CD4 T Cells in Nonobese Diabetic Mice with Tetramers Generated from I-Ag7/Class II-Associated Invariant Chain Peptide Precursors

2003 • 51 citations

Conserved T cell receptor α-chain induces insulin autoantibodies

2008 • 30 citations

Activation of Type B T Cells after Protein Immunization Reveals Novel Pathways of In Vivo Presentation of Peptides

2007 • 26 citations

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