Crystal structure of HLA-DP2 and implications for chronic beryllium disease

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

1997 • 10,943 citations

Scaling and assessment of data quality

2005 • 4,154 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 • 707 citations

Global indicators of X-ray data quality

2001 • 681 citations

MHC Class-II Molecules and Autoimmunity

1991 • 521 citations

HLA-DPB1 Glutamate 69: a Genetic Marker of Beryllium Disease

1993 • 450 citations

MHC class II proteins and disease: a structural perspective

2006 • 407 citations

Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme

1993 • 326 citations

Production of soluble MHC class II proteins with covalently bound single peptides

1994 • 302 citations

Proliferative Response of Bronchoalveolar Lymphocytes to Beryllium

1988 • 214 citations

Epidemiology of Beryllium Sensitization and Disease in Nuclear Workers

1993 • 202 citations

Machining risk of beryllium disease and sensitization with median exposures below 2 ?g/m3

1996 • 197 citations

A specific HLA-DP beta allele is associated with pauciarticular juvenile rheumatoid arthritis but not adult rheumatoid arthritis.

1989 • 150 citations

Differential Susceptibilities to Chronic Beryllium Disease Contributed by Different Glu69 HLA-DPB1 and -DPA1 Alleles

1999 • 146 citations

Beryllium presentation to CD4⁺T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease

2000 • 130 citations

Human Leukocyte Antigen Class II Amino Acid Epitopes

2002 • 126 citations

Beryllium disease screening in the ceramics industry. Blood lymphocyte test performance and exposure-disease relations.

1993 • 126 citations

BeF\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy}\usepackage{mathrsfs}\setlength{\oddsidemargin}{-69pt}\begin{document}\begin{equation*}{\mathrm{_{3}^{-}}}\end{equation*}\end{document} acts as a phosphate analog in proteins phosphorylated on aspartate: Structure of a BeF\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy}\…

2001 • 125 citations

Influence of MHC CLASS II in Susceptibility to Beryllium Sensitization and Chronic Beryllium Disease

2003 • 124 citations

HLA-DP Allele-Specific T Cell Responses to Beryllium Account for DP-Associated Susceptibility to Chronic Beryllium Disease

2001 • 114 citations

HLA-A and DPB1 loci confer susceptibility to Grave's disease

1992 • 113 citations

Recent contributions to the aqueous coordination chemistry of beryllium

2001 • 108 citations

Major Histocompatibility Complex-Directed Susceptibility to Rheumatoid Arthritis

1998 • 105 citations

Target organ localization of memory CD4+ T cells in patients with chronic beryllium disease

2002 • 94 citations

Susceptibility to hard metal lung disease is strongly associated with the presence of glutamate 69 in HLA‐DPβ chain

1997 • 90 citations

Target organ localization of memory CD4+ T cells in patients with chronic beryllium disease

2002 • 81 citations

The association between HLA‐DPB1^Glu69 and chronic beryllium disease and beryllium sensitization

2004 • 79 citations

Genetic susceptibility and immune-mediated destruction in beryllium-induced disease

2005 • 74 citations

Model for the Peptide-Free Conformation of Class II MHC Proteins

2008 • 65 citations

Beryllium Presentation to CD4+ T Cells Is Dependent on a Single Amino Acid Residue of the MHC Class II β-Chain

2005 • 63 citations

Beryllium binding to HLA-DP molecule carrying the marker of susceptibility to berylliosis glutamate β69

2001 • 62 citations

HLA-Linked susceptibility and resistance to Takayasu Arteritis

1992 • 46 citations

Detailed analysis of the effects of Glu/Lys beta69 human leukocyte antigen-DP polymorphism on peptide-binding specificity

2003 • 39 citations

Potential binding modes of beryllium with the class II major histocompatibility complex HLA-DP: a combined theoretical and structural database study

2003 • 39 citations

Recombinant HLA-DP2 Binds Beryllium and Tolerizes Beryllium-Specific Pathogenic CD4+ T Cells

2006 • 38 citations

Beryllium Chemical Speciation in Elemental Human Biological Fluids

2003 • 33 citations

Characterization of natural peptide ligands from HLA-DP2: new insights into HLA-DP peptide-binding motifs

2004 • 28 citations

Electrostatic potential on human leukocyte antigen: implications for putative mechanism of chronic beryllium disease.

2003 • 24 citations

Role of high‐affinity HLA‐DP specific CLIP‐derived peptides in beryllium binding to the HLA‐DPGlu69 berylliosis‐associated molecules and presentation to beryllium‐sensitized T cells

2008 • 15 citations