Back to search

Role of T lymphocytes in tumor response to radiotherapy

Data up to Jan 2025

Published2012
Citations159
References82

Total Citations Per Year

Abstract

References (82)

Hallmarks of Cancer: The Next Generation

2011 • 58,651 citations

The Hallmarks of Cancer

2000 • 27,569 citations

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

2010 • 14,016 citations

Innate Immune Recognition

2002 • 8,157 citations

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

2006 • 5,923 citations

Cancer immunoediting: from immunosurveillance to tumor escape

2002 • 4,911 citations

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

2002 • 4,625 citations

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

2011 • 3,283 citations

Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

2003 • 3,194 citations

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

2007 • 2,814 citations

The Three Es of Cancer Immunoediting

2004 • 2,781 citations

Microsatellite Instability in Colorectal Cancer

2010 • 2,013 citations

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

2012 • 1,925 citations

Natural Innate and Adaptive Immunity to Cancer

2011 • 1,878 citations

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

2009 • 1,694 citations

Adoptive immunotherapy for cancer: harnessing the T cell response

2012 • 1,570 citations

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

2006 • 1,499 citations

Interferons, immunity and cancer immunoediting

2006 • 1,497 citations

Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

2009 • 1,480 citations

Adaptive immunity maintains occult cancer in an equilibrium state

2007 • 1,307 citations

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

2004 • 1,253 citations

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

2005 • 1,246 citations

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

2011 • 1,226 citations

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

2012 • 1,160 citations

Immune infiltration in human tumors: a prognostic factor that should not be ignored

2009 • 1,020 citations

Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

2005 • 940 citations

Systemic effects of local radiotherapy

2009 • 906 citations

Local Radiation Therapy of B16 Melanoma Tumors Increases the Generation of Tumor Antigen-Specific Effector Cells That Traffic to the Tumor

2005 • 894 citations

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages

2000 • 864 citations

Cell death modalities: classification and pathophysiological implications

2007 • 772 citations

Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells

2008 • 650 citations

Immune parameters affecting the efficacy of chemotherapeutic regimens

2011 • 622 citations

The grateful dead: damage‐associated molecular pattern molecules and reduction/oxidation regulate immunity

2007 • 616 citations

Sublethal Irradiation of Human Tumor Cells Modulates Phenotype Resulting in Enhanced Killing by Cytotoxic T Lymphocytes

2004 • 532 citations

Perforin and interferon-γ activities independently control tumor initiation, growth, and metastasis

2001 • 529 citations

Decoding Cell Death Signals in Inflammation and Immunity

2010 • 519 citations

Expression of tumour-specific antigens underlies cancer immunoediting

2012 • 501 citations

In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study

2010 • 467 citations

Irradiation of Tumor Cells Up-Regulates Fas and Enhances CTL Lytic Activity and CTL Adoptive Immunotherapy

2003 • 452 citations

Radiation-Induced IFN-γ Production within the Tumor Microenvironment Influences Antitumor Immunity

2008 • 436 citations

External Beam Radiation of Tumors Alters Phenotype of Tumor Cells to Render Them Susceptible to Vaccine-Mediated T-Cell Killing

2004 • 425 citations

TLR-dependent T cell activation in autoimmunity

2011 • 421 citations

Epitope Landscape in Breast and Colorectal Cancer

2008 • 408 citations

Lymphoproliferation in CTLA-4–Deficient Mice Is Mediated by Costimulation-Dependent Activation of CD4 + T Cells

1997 • 405 citations

Combining a Recombinant Cancer Vaccine with Standard Definitive Radiotherapy in Patients with Localized Prostate Cancer

2005 • 373 citations

Radiation Enhances Regulatory T Cell Representation

2010 • 368 citations

[Whole body irradiation].

1992 • 364 citations

A Sense of Danger from Radiation1

2004 • 317 citations

Workshop R: Tumor Immunology, Abstract R1 bis R30

2001 • 312 citations

Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies

2012 • 265 citations

Isoform-Specific Activation of Latent Transforming Growth Factor β (LTGF-β) by Reactive Oxygen Species

2006 • 256 citations

Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases

2005 • 241 citations

Effect of Host Immune Capability on Radiocurability and Subsequent Transplantability of a Murine Fibrosarcoma<xref ref-type="fn" rid="FN2">2</xref>

1979 • 236 citations

Transplant tumor registry: donor related malignancies

2002 • 231 citations

Cell intrinsic mechanisms of T‐cell inhibition and application to cancer therapy

2008 • 219 citations

Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer.

1999 • 211 citations

Chemotherapy and radiotherapy: Cryptic anticancer vaccines

2010 • 189 citations

DNA damage and autophagy

2011 • 185 citations

Cutting Edge: Tumor Rejection Mediated by NKG2D Receptor-Ligand Interaction Is Dependent upon Perforin

2002 • 181 citations

Combination of Conformal Radiotherapy and Intratumoral Injection of Adoptive Dendritic Cell Immunotherapy in Refractory Hepatoma

2005 • 181 citations

Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation

2006 • 175 citations

The Combination of Ionizing Radiation and Peripheral Vaccination Produces Long-term Survival of Mice Bearing Established Invasive GL261 Gliomas

2006 • 159 citations

Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro

1997 • 159 citations

Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration.

2003 • 158 citations

Addicted to Death

2004 • 157 citations

Targeting Toll-like Receptor 9 with CpG Oligodeoxynucleotides Enhances Tumor Response to Fractionated Radiotherapy

2005 • 152 citations

CpG Oligodeoxynucleotide Enhances Tumor Response to Radiation

2004 • 146 citations

Combination of ?-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice: Approach to treatment of advanced stage cancer

2001 • 131 citations

Sensors of ionizing radiation effects on the immunological microenvironment of cancer

2007 • 120 citations

Combination of External Beam Radiotherapy (EBRT) With Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients

2011 • 114 citations

Immune selective pressure and HLA class I antigen defects in malignant lesions

2006 • 114 citations

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

2006 • 101 citations

Intratumour T cells, their activation status and survival in gastric carcinomas characterised for microsatellite instability and Epstein–Barr virus infection

2005 • 88 citations

Direct injection of immature dendritic cells into irradiated tumor induces efficient antitumor immunity

2004 • 82 citations

Radiotherapy Enhances Antitumor Effect of Anti-CD137 Therapy in a Mouse Glioma Model

2010 • 67 citations

Effect of radiation on the expression of carcinoembryonic antigen of human gastric adenocarcinoma cells

1991 • 64 citations

Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy

2008 • 44 citations

Tumor microvasculature as a barrier to antitumor immunity

2003 • 40 citations

Translational Research Working Group Developmental Pathway for Immune Response Modifiers

2008 • 36 citations

A sense of danger

1962 • 5 citations

Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

1998 • 5 citations

Immune Escape: Immunosuppressive Networks

2007 • 2 citations

Cited By (0)

Loading...
Role of T lymphocytes in tumor response to radiotherapy (2012) – Frontiers in Oncology | Metascience Observatory Explorer