Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

2007 • 2,814 citations

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

2004 • 1,253 citations

Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

2005 • 940 citations

Local Radiation Therapy of B16 Melanoma Tumors Increases the Generation of Tumor Antigen-Specific Effector Cells That Traffic to the Tumor

2005 • 894 citations

Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells

2008 • 650 citations

The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

2007 • 531 citations

Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma

2005 • 462 citations

Combining a Recombinant Cancer Vaccine with Standard Definitive Radiotherapy in Patients with Localized Prostate Cancer

2005 • 373 citations

Innovations in image-guided radiotherapy

2007 • 361 citations

Combining radiotherapy and immunotherapy: A revived partnership

2005 • 349 citations

Anti–Cytotoxic T-Lymphocyte Antigen-4 Antibody: The First in an Emerging Class of Immunomodulatory Antibodies for Cancer Treatment

2008 • 311 citations

Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis

1998 • 266 citations

Induction of adenocarcinomas of the colon in mice by weekly injections of 1,2-dimethylhydrazine.

1973 • 229 citations

Combination of Conformal Radiotherapy and Intratumoral Injection of Adoptive Dendritic Cell Immunotherapy in Refractory Hepatoma

2005 • 181 citations

Gene Expression Profiling of Breast, Prostate, and Glioma Cells following Single versus Fractionated Doses of Radiation

2007 • 181 citations

Alloreactive cytotoxic T lymphocytes generated in the presence of viral-derived peptides show exquisite peptide and MHC specificity.

1993 • 150 citations

Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12.

1999 • 141 citations

T-Cell Responses to Survivin in Cancer Patients Undergoing Radiation Therapy

2008 • 140 citations

Sensors of ionizing radiation effects on the immunological microenvironment of cancer

2007 • 120 citations

Abscopal effect of radiation in papillary adenocarcinoma

1973 • 110 citations

Safety and Immunologic Response of a Viral Vaccine to Prostate-Specific Antigen in Combination with Radiation Therapy when Metronomic-Dose Interleukin 2 Is Used as an Adjuvant

2008 • 110 citations

Invariant Natural Killer T Cells Regulate Breast Cancer Response to Radiation and CTLA-4 Blockade

2009 • 96 citations

The abscopal effect: Demonstration in lymphomatous involvement of kidneys

1981 • 60 citations

Local control by radiotherapy: is that all there is?

2008 • 56 citations

The cytotoxic T-lymphocyte response against a poorly immunogenic mammary adenocarcinoma is focused on a single immunodominant class I epitope derived from the gp70 Env product of an endogenous retrovirus.

2003 • 42 citations

Mechanism and Therapeutic Reversal of Immune Suppression in Cancer

2007 • 40 citations

Disease control and long-term survival in chemotherapy-naive patients with advanced melanoma treated with ipilimumab (MDX- 010) with or without dacarbazine

2008 • 32 citations