Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation

The cellular and molecular basis of hyperthermia

2002 • 1,594 citations

Roles of the NKG2D immunoreceptor and its ligands

2003 • 1,297 citations

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

2005 • 1,246 citations

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells

1998 • 1,134 citations

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

1996 • 1,010 citations

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages

2000 • 864 citations

New aspects of natural-killer-cell surveillance and therapy of cancer

2002 • 713 citations

Retinoic Acid Early Inducible Genes Define a Ligand Family for the Activating NKG2D Receptor in Mice

2000 • 694 citations

A New Era for Cancer Immunotherapy Based on the Genes that Encode Cancer Antigens

1999 • 578 citations

Heat shock factors and the control of the stress response

2000 • 568 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

Human natural killer cell development and biology

2005 • 487 citations

What does it take to make a natural killer?

2003 • 481 citations

External Beam Radiation of Tumors Alters Phenotype of Tumor Cells to Render Them Susceptible to Vaccine-Mediated T-Cell Killing

2004 • 425 citations

Implications of increased tumor blood flow and oxygenation caused by mild temperature hyperthermia in tumor treatment

2005 • 273 citations

UL16-Binding Proteins, Novel MHC Class I-Related Proteins, Bind to NKG2D and Activate Multiple Signaling Pathways in Primary NK Cells

2002 • 272 citations

Cancer Cells Become Susceptible to Natural Killer Cell Killing after Exposure to Histone Deacetylase Inhibitors Due to Glycogen Synthase Kinase-3–Dependent Expression of MHC Class I–Related Chain A and B

2005 • 260 citations

Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+increase are reciprocally modulated in rat cardiomyocytes

2006 • 254 citations

Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein

2002 • 240 citations

The enigma of the natural killer cell

1995 • 236 citations

NK cells and the tumour microenvironment: implications for NK-cell function and anti-tumour activity

2003 • 223 citations

Lymphocyte activation via NKG2D: towards a new paradigm in immune recognition?

2002 • 206 citations

Immune Modulation by Ionizing Radiation and its Implications for Cancer Immunotherapy

2002 • 200 citations

ULBP1, 2, 3: novel MHC class I-related molecules that bind to human cytomegalovirus glycoprotein UL16, activate NK cells

2001 • 155 citations

Putting the natural killer cell in its place

2005 • 150 citations

Augmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermia

2001 • 118 citations

Intratumoral injection of immature dendritic cells enhances antitumor effect of hyperthermia using magnetic nanoparticles

2005 • 118 citations

Human Natural Killer cell receptors: insights into their molecular function and structure

2003 • 104 citations

Regulation of NKG2D Ligand Gene Expression

2006 • 100 citations

Tumour escape: antitumour effectors too much of a good thing?

2004 • 87 citations

Direct injection of immature dendritic cells into irradiated tumor induces efficient antitumor immunity

2004 • 82 citations

The NKG2D receptor and its ligands–recognition beyond the “missing self”?

2003 • 78 citations

Catechins inhibit angiotensin II-induced vascular smooth muscle cell proliferation via mitogen-activated protein kinase pathway

2006 • 68 citations

Binding between wild-type p53 and hsp72 accumulated after UV and γ-ray irradiation

1995 • 65 citations

Loss of HLA molecules in B lymphomas is associated with an aggressive clinical course

1998 • 64 citations

Effects of Irradiation on the Expression of Surface Antigens in Human Ovarian Cancer

1996 • 36 citations

New directions in natural killer cell-based immunotherapy of human cancer

2003 • 35 citations

Activated natural killer cell-mediated immunity is required for the inhibition of tumor metastasis by dendritic cell vaccination

2004 • 31 citations

Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells

2005 • 29 citations

Combined radiation therapy and dendritic cell vaccine for treating solid tumors with liver micro‐metastasis

2004 • 28 citations

The effects of irradiation on the expression of a tumour rejection antigen (heat shock protein gp96) in human cervical cancer

1998 • 28 citations

Cancer immunotherapy and heat-shock proteins: promises and challenges

2004 • 25 citations

Heat Shock Enhances the Susceptibility of Tumor Cells to Lysis by Lymphokine-Activated Killer Cells

1995 • 25 citations

X-irradiation to human malignant glioma cells enhances the cytotoxicity of autologous killer lymphocytes under specific conditions

2004 • 21 citations

Combined hyperthermia and immunotherapy treatment of multiple pulmonary metastases in mice

1994 • 12 citations

New directions in natural killer cell-based immunotherapy of human cancer

2003 • 3 citations

Cancer immunotherapy and heat-shock proteins: promises and challenges

2004 • 2 citations