Activation of Peroxisome Proliferator-Activated Receptors (PPARs) by Their Ligands and Protein Kinase A Activators
Data up to Jan 2025
Total Citations Per Year
Abstract
References (58)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
The nuclear receptor superfamily: The second decade
1995 • 6,929 citations
Chapter 4 Preparation of Isolated Rat Liver Cells
1976 • 5,335 citations
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 • 3,462 citations
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 • 2,880 citations
Steroid hormone receptors: Many Actors in search of a plot
1995 • 1,854 citations
Nuclear Receptor Coregulators: Cellular and Molecular Biology*
1999 • 1,783 citations
Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators
1995 • 1,626 citations
Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting
1999 • 1,589 citations
Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.
1990 • 1,507 citations
Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
1992 • 1,362 citations
The PPARα–leukotriene B4 pathway to inflammation control
1996 • 1,328 citations
Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay
1997 • 1,158 citations
Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARγ
1996 • 1,033 citations
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders
1999 • 931 citations
Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)
1998 • 851 citations
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors.
1986 • 733 citations
Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription.
1994 • 667 citations
Transcriptional Activation by Peroxisome Proliferator-activated Receptor γ Is Inhibited by Phosphorylation at a Consensus Mitogen-activated Protein Kinase Site
1997 • 544 citations
Peroxisome proliterator-activated receptors, orphans with ligands and functions
1997 • 494 citations
Regulation of Peroxisome Proliferator-activated Receptor γ Activity by Mitogen-activated Protein Kinase
1997 • 446 citations
The structure of the nuclear hormone receptors
1999 • 414 citations
Peroxisome Proliferator-activated Receptor α-Isoform Deficiency Leads to Progressive Dyslipidemia with Sexually Dimorphic Obesity and Steatosis
1998 • 395 citations
Interdomain communication regulating ligand binding by PPAR-γ
1998 • 344 citations
Polarity and Specific Sequence Requirements of Peroxisome Proliferator-activated Receptor (PPAR)/Retinoid X Receptor Heterodimer Binding to DNA
1997 • 342 citations
Expression of the Peroxisome Proliferator-activated Receptor α Gene Is Stimulated by Stress and Follows a Diurnal Rhythm
1996 • 317 citations
Ligand-independent Activation Domain in the N Terminus of Peroxisome Proliferator-activated Receptor γ (PPARγ)
1997 • 276 citations
Androgen-independent Induction of Prostate-specific Antigen Gene Expression via Cross-talk between the Androgen Receptor and Protein Kinase A Signal Transduction Pathways
1999 • 273 citations
Insulin- and Mitogen-activated Protein Kinase-mediated Phosphorylation and Activation of Peroxisome Proliferator-activated Receptor γ
1996 • 272 citations
Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization
1999 • 254 citations
Peroxisome Proliferator-activated Receptor α Controls the Hepatic CYP4A Induction Adaptive Response to Starvation and Diabetes
1998 • 211 citations
Progesterone Receptor Regulation in Uterine Cells:Stimulation by Estrogen, Cyclic Adenosine 3′,5′-Monophosphate, and Insulin-Like Growth Factor I andSuppression by Antiestrogens and Protein KinaseInhibitors*
1991 • 203 citations
Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activators.
1993 • 197 citations
The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin.
1996 • 179 citations
Protein Kinase A-Dependent Phosphorylation Modulates DNA-Binding Activity of Hepatocyte Nuclear Factor 4
1997 • 179 citations
Regulation of the Transcriptional Activity of the Peroxisome Proliferator-activated Receptor α by Phosphorylation of a Ligand-independent trans-Activating Domain
1999 • 174 citations
Modulation of glucocorticoid receptor function by protein kinase A.
1992 • 162 citations
Two Separate Mechanisms for Ligand-Independent Activation of the Estrogen Receptor
1997 • 153 citations
Phosphorylation of the retinoic acid receptor-alpha by protein kinase A.
1995 • 122 citations
Alteration in the agonist/antagonist balance of antiestrogens by activation of protein kinase A signaling pathways in breast cancer cells: antiestrogen selectivity and promoter dependence.
1994 • 122 citations
Phosphorylation of activation functions AF-1 and AF-2 of RARalpha and RARgamma is indispensable for differentiation of F9 cells upon retinoic acid and cAMP treatment
1997 • 114 citations
A Carboxyl-terminal Extension of the Zinc Finger Domain Contributes to the Specificity and Polarity of Peroxisome Proliferator-activated Receptor DNA Binding
1998 • 108 citations
Mechanistic Aspects of Estrogen Receptor Activation Probed with Constitutively Active Estrogen Receptors: Correlations with DNA and Coregulator Interactions and Receptor Conformational Changes
1997 • 85 citations
Modulation of Human Mineralocorticoid Receptor Function by Protein Kinase A
1999 • 69 citations
Activation of transcriptionally inactive human estrogen receptors by cyclic adenosine 3',5'-monophosphate and ligands including antiestrogens.
1994 • 65 citations
Adenovirus-Mediated Delivery of a Dominant Negative Estrogen Receptor Gene Abrogates Estrogen-Stimulated Gene Expression and Breast Cancer Cell Proliferation
1999 • 62 citations
Mutations in the Activation Function-2 Core Domain of Steroidogenic Factor-1 Dominantly Suppresses PKA-dependent Transactivation of the Bovine CYP17 Gene
1998 • 44 citations
Characterization of the Amino-terminal Activation Domain of Peroxisome Proliferator-activated Receptor α
1999 • 44 citations
Mechanisms of catecholamine effects on ketogenesis
1984 • 39 citations
Phosphorylation of peroxisome proliferator-activated receptor α in rat Fao cells and stimulation by ciprofibrate
1999 • 38 citations
Comparison of Dose–Response Relationships for Induction of Lipid Metabolizing and Growth Regulatory Genes by Peroxisome Proliferators in Rat Liver
1998 • 37 citations
Plasma cAMP: a hepatorenal link influencing proximal reabsorption and renal hemodynamics?
1997 • 30 citations
Characterization of the AB (AF-1) region in the muscle-specific retinoid X receptor-gamma: evidence that the AF-1 region functions in a cell-specific manner
1996 • 25 citations
Responsiveness to Thyroid Hormone is Enhanced in Rat Hepatocytes Cultured as Spheroids Compared with that in Monolayers: Altered Responsiveness to Thyroid Hormone Possibly Involves Complex Formed on Thyroid Hormone Response Elements
1999 • 19 citations
Synergistic Enhancement of PRB-Mediated RU486 and R5020 Agonist Activities through Cyclic Adenosine 3′,5′-Monophosphate Represents a Delayed Primary Response
1998 • 16 citations
Role of cAMP in mediating effects of fasting on dephosphorylation of insulin receptor
1992 • 14 citations
Control of fructose 2,6-diphosphate in muscle of exercising fasted rats
1992 • 13 citations