Adenosine A₁‐receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT₁ MF‐2 cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

Subclasses of external adenosine receptors.

1980 • 1,087 citations

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

1989 • 537 citations

On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins

1986 • 510 citations

<scp>l</scp>‐N^G‐nitro arginine methyl ester exhibits antinociceptive activity in the mouse

1991 • 481 citations

Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes

1987 • 376 citations

2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis

1982 • 251 citations

Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor.

1990 • 190 citations

INHIBITION OF CYCLO-OXYGENASE AND LIPOXYGENASE

1983 • 158 citations

ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.

1992 • 132 citations

Distinct pathways of desensitization of A1- and A2-adenosine receptors in DDT1 MF-2 cells.

1991 • 126 citations

Adenosine receptors: structure, function and regulation

1986 • 124 citations

Vigabatrin in the treatment of epilepsy in children.

1989 • 118 citations

Pharmacological profile of AA-861, A 5-lipoxygenase inhibitor

1983 • 111 citations

PD 115,199: An antagonist ligand for adenosine A2 receptors

1987 • 96 citations

Receptors that inhibit phosphoinositide breakdown

1989 • 88 citations

Adenosine stimulates guanylate cyclase activity in vascular smooth muscle cells.

1987 • 88 citations

Regulation of GH3-cell function via adenosine A1 receptors. Inhibition of prolactin release, cyclic AMP production and inositol phosphate generation

1988 • 87 citations

Adenosine Receptor Subtypes: Binding Studies

1987 • 85 citations

Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow

1986 • 81 citations

Calcium influx in a rat mast cell (RBL-2H3) line. Use of multivalent metal ions to define its characteristics and role in exocytosis

1991 • 69 citations

Characterization of adenosine A1 receptors in intact DDT1 MF-2 smooth muscle cells.

1990 • 67 citations

Studies on the adenosine‐receptor mediating the augmentation of histamine‐induced inositol phospholipid hydrolysis in guinea‐pig cerebral cortex

1987 • 67 citations

Cross-talk between different receptor-effector systems in the mammalian CNS

1989 • 58 citations

Glucocorticoid receptor activation leads to up-regulation of adenosine A1 receptors and down-regulation of adenosine A2 responses in DDT1 MF-2 smooth muscle cells.

1991 • 57 citations

Accumulations of inositol phosphates and cyclic AMP in brain slices: Synergistic interactions of histamine and 2-chloroadenosine

1986 • 57 citations

Studies on the receptor mediating cyclic AMP‐independent enhancement by adenosine of IgE‐dependent mediator release from rat mast cells

1986 • 56 citations

Differences in the adenosine receptors modulating inositol phosphates and cyclic AMP accumulation in mammalian cerebral cortex

1989 • 56 citations

Adenosine Inhibition of Histamine‐Stimulated Inositol Phospholipid Hydrolysis in Mouse Cerebral Cortex

1988 • 54 citations

Demonstration of both A1 and A2 adenosine receptors in DDT1 MF-2 smooth muscle cells.

1990 • 52 citations

Adenosine A₁‐receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT₁ MF‐2 cells

1992 • 41 citations

Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction

1990 • 39 citations

1,3,8‐ and 1,3,7‐substituted xanthines: relative potency as adenosine receptor antagonists at the frog neuromuscular junction

1989 • 39 citations

Pharmacological classification of receptors for adenyl purines in guinea pig myometrium.

1988 • 26 citations

Possible involvement of prostaglandins in the action of ATP on guinea-pig uterus.

1979 • 26 citations

Action of adenosine in estrogen-primed nonpregnant guinea pig myometrium: characterization of the smooth muscle receptor and coupling to phosphoinositide metabolism.

1991 • 23 citations

Smooth muscle adenosine A1 receptors couple to disparate effectors by distinct G proteins in pregnant myometrium

1991 • 23 citations

Adenosine Inhibits Histamine‐Induced Phosphoinositide Hydrolysis Mediated via Pertussis Toxin‐Sensitive G Protein in Human Astrocytoma Cells

1991 • 21 citations

Measuring muscarinic antagonist potency using stimulated phosphoinositide breakdown in rat cortex slices

1987 • 14 citations

Expression of beta2-adrenoceptors mediating cyclic AMP accumulation in astroglial and neuronal cell lines derived from the rat CNS

1990 • 12 citations