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2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis

Data up to Jan 2025

Published1982
Citations251
References17

Total Citations Per Year

Abstract

References (17)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

1976 • 668 citations

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

1976 • 638 citations

Arachidonate lipoxygenase in blood platelets

1975 • 613 citations

A new approach to anti-inflammatory drugs

1979 • 501 citations

Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid.

1980 • 330 citations

On the formation of thromboxane B2 and 12L-hydroxy-5, 8,10,14-eicosatetraenoic acid (12 ho-20:4) in tissues from the guinea pig

1976 • 277 citations

Leukotrienes and Slow Reacting Substance of Anaphylaxis (SRS‐A)

1980 • 228 citations

Effect of temperature and antioxidants upon the lipoxidase-catalyzed oxidation of sodium linoleate

1953 • 206 citations

Inhibition of prostaglandin biosynthesis by eicosa-5,8,11,14-tetraynoic acid

1970 • 132 citations

Enzymatic assembly of slow reacting substance

1980 • 122 citations

Inhibition of rabbit PMN lipoxygenase activity by benoxaprofen

1979 • 98 citations

The inhibitory effects of BW 755C on arachidonic acid metabolism in human polymorphonuclear leukocytes

1980 • 79 citations

The production of 5-HETE and leukotriene B in rat neutrophils from carrageenan pleural exudates

1981 • 75 citations

The role of arachidonate lipoxygenase in the release of SRS-A from guinea-pig chopped lung

1980 • 70 citations

The effect of thiols on the immunologic release of slow reacting substance of anaphylaxis. II. Other in vitro and in vivo models.

1976 • 45 citations

The Effect of Thiols on the Immunologic Release of Slow Reacting Substance of Anaphylaxis

1976 • 33 citations

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2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective… (1982) – Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | Metascience Observatory Explorer