Calcium influx in a rat mast cell (RBL-2H3) line. Use of multivalent metal ions to define its characteristics and role in exocytosis

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration

1986 • 489 citations

Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes.

1983 • 466 citations

The mechanism of the calcium signal and correlation with histamine release in 2H3 cells.

1984 • 351 citations

Highly Cooperative Opening of Calcium Channels by Inositol 1,4,5-Trisphosphate

1988 • 307 citations

Uptake and intracellular sequestration of divalent cations in resting and methacholine-stimulated mouse lacrimal acinar cells. Dissociation by Sr2+ and Ba2+ of agonist-stimulated divalent cation entry from the refilling of the agonist-sensitive intracellular pool.

1990 • 298 citations

The relationship between histamine secretion and ⁴⁵calcium‐uptake by mast cells

1977 • 265 citations

Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+

1989 • 248 citations

Characterization of the Bradykinin-stimulated Calcium Influx Pathway of Cultured vascular Endothelial Cells

1989 • 224 citations

Pathways of Ca2+ influx at the plasma membrane: Voltage-, receptor-, and second messenger-operated channels

1987 • 223 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

The role of the alkaline earth ions in anaphylactic histamine secretion

1972 • 210 citations

Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor.

1990 • 190 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

Antigen-induced Secretion of Histamine and the Phosphorylation of Myosin by Protein Kinase C in Rat Basophilic Leukemia Cells

1989 • 161 citations

Depolarization of rat basophilic leukemia cells inhibits calcium uptake and exocytosis.

1987 • 132 citations

Direct demonstration of increased intracellular concentration of free calcium as measured by quin-2 in stimulated rat peritoneal mast cell.

1984 • 118 citations

2 Calcium and Histamine Secretion from Mast Cells

1982 • 114 citations

Immunoglobulin E Receptor Cross-linking Induces Oscillations in Intracellular Free Ionized Calcium in Individual Tumor Mast Cells

1989 • 113 citations

Diacylglycerol metabolism in mast cells. Analysis of lipid metabolic pathways using molecular species analysis of intermediates.

1987 • 112 citations

An indirect pathway of receptor-mediated 1,2-diacylglycerol formation in mast cells. I. IgE receptor-mediated activation of phospholipase D.

1990 • 109 citations

IgE-mediated histamine release in rat basophilic leukemia cells: Receptor activation, phospholipid methylation, Ca2+ flux, and release of arachidonic acid

1981 • 103 citations

Calcium shares the limelight in stimulus-secretion coupling

1986 • 97 citations

The cromolyn binding protein constitutes the Ca2+ channel of basophils opening upon immunological stimulus.

1984 • 92 citations

Membrane Phosphoinositide-Activated Signals in Mast Cells and Basophils1

2015 • 91 citations

Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release.

1987 • 90 citations

Studies of protein kinase C in the rat basophilic leukemia (RBL-2H3) cell reveal that antigen-induced signals are not mimicked by the actions of phorbol myristate acetate and Ca2+ ionophore.

1989 • 71 citations

Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.

1988 • 69 citations

The action of lanthanum and manganese on anaphylactic histamine secretion

1973 • 66 citations

The relative contributions of extracellular and intracellular calcium to secretion from tumor mast cells. Multiple effects of the proton ionophore carbonyl cyanide m-chlorophenylhydrazone.

1987 • 61 citations

Cholera toxin increases the rate of antigen-stimulated calcium influx in rat basophilic leukemia cells.

1988 • 60 citations

A patch-clamp study: secretagogue-induced currents in rat peritoneal mast cells

1989 • 59 citations

Initial Characterization of the Calcium Channel Activated by the Crosslinking of the Receptors for Immunoglobulin E *

1986 • 55 citations

Assessment of IgE-receptor function through measurement of hydrolysis of membrane inositol phospholipids. New insights on the phenomena of biphasic antigen concentration-response curves and desensitization.

1988 • 54 citations

Phospholipase A2 stimulation during cell secretion in rat basophilic leukemia cells.

1986 • 54 citations

Modulation of histamine release from human basophils in vitro by physiological concentrations of zinc.

1981 • 50 citations

The rise in concentration of free Ca2+ and of pH provides sequential, synergistic signals for secretion in antigen-stimulated rat basophilic leukemia (RBL-2H3) cells.

1989 • 50 citations

Effects of smooth muscle calcium antagonists on human basophil histamine release

1981 • 50 citations

The control of mediator release from RBL-2H3 cells: roles for Ca2+, Na+, and protein kinase C1.

1987 • 50 citations

Restoration of Ca ²⁺ influx and degranulation capacity of variant RBL-2H3 cells upon implantation of isolated cromolyn binding protein

1983 • 47 citations

IgE receptor-activated calcium permeability pathway in rat basophilic leukemia cells: measurement of the unidirectional influx of calcium using quin2-buffered cells

1987 • 46 citations

Isolation of a basophilic membrane protein binding the anti-allergic drug cromolyn.

1982 • 45 citations

Receptor-mediated release of inositol 1,4,5-trisphosphate and inositol 1,4-bisphosphate in rat basophilic leukemia RBL-2H3 cells permeabilized with streptolysin O

1989 • 42 citations

Initial characterization of the calcium channel activated by the cross-linking of the receptors for immunoglobulin E.

1984 • 41 citations

Activation of Basophils and Mast Cells for Mediator Release

1987 • 38 citations

Movement of strontium ions into mast cells and its relationship to the secretory response

1977 • 35 citations

The interaction of calcium and strontium with phosphatidyl serine in the anaphylactic secretion of histamine

1973 • 34 citations

Calcium specificity of the antigen-induced channels in rat basophilic leukemia cells

1988 • 25 citations

Evaluation of calcium entry blockers in several models of immediate hypersensitivity.

1984 • 24 citations

Characterization of the ion channel activity in planar bilayers containing IgE-Fc epsilon receptor and the cromolyn-binding protein.

1986 • 22 citations

Isolation and purification of an Fc.epsilon. receptor activated ion channel from the rat mast cell line RBL-2H3

1988 • 19 citations

The Action of Strontium on Basophil Leukocytes and its Use to Probe the Relationship between Immunologic Stimulus and Secretory Response

1979 • 15 citations

Release of calcium from intracellular stores in rat basophilic leukemia cells monitored with the fluorescent probe chlortetracycline

1990 • 11 citations