On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart1

1929 • 1,470 citations

Fitting and Statistical Analysis of Single-Channel Records

1983 • 1,098 citations

Calcium tolerant ventricular myocytes prepared by preincubation in a ?KB medium?

1982 • 917 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.

1982 • 808 citations

Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

1985 • 732 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres

1968 • 488 citations

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

1983 • 471 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

The control of the metabolism and the hormonal role of adenosine.

1978 • 416 citations

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.

1984 • 411 citations

Adenosine as inhibitor of myocardial effects of catecholamines

1977 • 364 citations

Inward-rectifying channels in isolated patches of the heart cell membrane: ATP-dependence and comparison with cell-attached patches

1984 • 333 citations

Reconstitution of resolved muscarinic cholinergic receptors with purified GTP-binding proteins.

1985 • 314 citations

Isolated atrial myocytes: adenosine and acetylcholine increase potassium conductance

1983 • 277 citations

Studies of calcium channels in rat clonal pituitary cells with patch electrode voltage clamp

1982 • 272 citations

Adenosine-activated potassium conductance in cultured striatal neurons.

1985 • 253 citations

Interaction between cyclic adenosine monophosphate and cyclic gunaosine monophosphate in guinea pig ventricular myocardium.

1975 • 228 citations

The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein

1983 • 215 citations

Voltage‐dependent activation of the inward‐rectifier potassium channel in the ventricular cell membrane of guinea‐pig heart.

1985 • 202 citations

Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell

1978 • 200 citations

Actions of adenosine and isoproterenol on isolated mammalian ventricular myocytes.

1983 • 199 citations

Intracellular analysis of a postsynaptic action of adenosine in the rat hippocampus

1982 • 167 citations

The effect of intracellular cyclic nucleotides and calcium on the action potential and acetylcholine response of isolated cardiac cells

1982 • 164 citations

Ionic basis for the antagonism between adenosine and isoproterenol on isolated mammalian ventricular myocytes.

1984 • 150 citations

Electrical properties of cardiac muscle attributable to inward going (anomalous) rectification

1965 • 138 citations

Reduction by adenosine of the isoproterenol-induced increase in cyclic adenosine 3',5'-monophosphate formation and glycogen phosphorylase activity in rat heart muscle.

1978 • 135 citations

Time course of the increase in the myocardial slow inward current after a photochemically generated concentration jump of intracellular cAMP.

1983 • 132 citations

Isolation of calcium current and its sensitivity to monovalent cations in dialysed ventricular cells of guinea‐pig.

1984 • 132 citations

Adenosine enhances afterhyperpolarization and accommodation in hippocampal pyramidal cells

1984 • 125 citations

Adenosine receptors in frog sinus venosus: slow inhibitory potentials produced by adenine compounds and acetylcholine.

1979 • 118 citations

Specificity of adenosine uptake into the heart and inhibition by dipyridamole

1970 • 106 citations

The mechanism by which adenosine and cholinergic agents reduce contractility in rat myocardium. Correlation with cyclic adenosine monophosphate and receptor densities.

1985 • 105 citations

Membrane currents and their modification by acetylcholine in isolated single atrial cells of the guinea‐pig.

1985 • 105 citations

The effects of intracellular protons on the electrical activity of single ventricular cells

1982 • 104 citations

Attenuation of muscarinic cholinergic inhibition by islet-activating protein in the heart

1985 • 95 citations

Adenosine mediates a slow hyperpolarizing synaptic potential in autonomic neurones

1984 • 84 citations

Correlation of sinus slowing and hyperpolarization caused by adenosine in sinus node

1985 • 83 citations

Effects of acetylcholine and parasympathetic nerve stimulation on membrane potential in quiescent guinea‐pig atria.

1978 • 79 citations

Responses in the rat thalamus to whisker movements produced by motor nerve stimulation

1974 • 73 citations

Pertussis toxin treatment blocks hyperpolarization by muscarinic agonists in chick atrium.

1985 • 71 citations

Myocardial adenosine formation with increased cardiac performance in the dog

1979 • 67 citations

Effect of Acetylcholine and Adenosine on Cardiac Cellular Potentials

1956 • 64 citations

Muscarinic inhibitory transmission in mammalian sympathetic ganglia mediated by increased potassium conductance

1984 • 63 citations

The time course of the muscarinic response to ionophoretic acetylcholine application to the S-A node of the rabbit heart

1981 • 56 citations

Potassium currents in frog ventricular muscle: evidence from voltage clamp currents and extracellular K accumulation.

1979 • 49 citations

Effects of acetylcholine on electrophysiological properties of rabbit cardiac Purkinje fibers.

1983 • 49 citations

Muscarinic antagonism of the effects of phosphodiesterase inhibitor (methylisobutylxanthine) in embryonic chick ventricle.

1980 • 43 citations

Purinergic Receptors

1981 • 39 citations

Comparison of the adenine nucleotide metabolism of dog atrial and ventricular myocardium,

1975 • 34 citations

Sites of Action and Production of Adenosine in the Heart

1981 • 27 citations

Proceedings: Effects of adrenaline on membrane currents underlying pacemaker activity in frog atrial muscle.

1974 • 25 citations

"Fade" of hyperpolarizing responses to vagal stimulation at the sinoatrial and atrioventricular nodes of the rabbit heart.

1985 • 21 citations

Desensitization of the muscarinic acetylcholine receptor of atrium in bullfrogs.

1981 • 16 citations

Insulin Blockade of Epinephrine

1970 • 9 citations

Papaverine enhances the effect of adenosine in guinea-pig atria

1984 • 3 citations