Back to search

High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells

Data up to Jan 2025

Published2004
Citations77
References60

Total Citations Per Year

Abstract

References (60)

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

Direct isolation of human central nervous system stem cells

2000 • 1,822 citations

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1998 • 1,687 citations

A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes

1992 • 1,514 citations

The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

1997 • 1,414 citations

Clonal and Population Analyses Demonstrate That an EGF-Responsive Mammalian Embryonic CNS Precursor Is a Stem Cell

1996 • 1,366 citations

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4

2002 • 1,335 citations

Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy

2003 • 1,259 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses

2000 • 1,077 citations

Isolation, Characterization, and use of Stem Cells from the CNS

1995 • 819 citations

Identification of major cell classes in the developing mammalian nervous system

1985 • 803 citations

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide

2003 • 758 citations

bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells

1993 • 651 citations

Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain

2003 • 640 citations

NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4

2003 • 624 citations

HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver

2003 • 595 citations

The expression and posttranslational modification of a neuron‐specific β‐tubulin isotype during chick embryogenesis

1990 • 589 citations

Hematopoietic Stem Cells Are Uniquely Selective in Their Migratory Response to Chemokines

2002 • 518 citations

In Vitro Expansion of a Multipotent Population of Human Neural Progenitor Cells

1999 • 501 citations

Regulation of neurogenesis by growth factors and neurotransmitters

1998 • 483 citations

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4

1998 • 419 citations

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

2002 • 413 citations

Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4

1998 • 411 citations

In vitro -generated neural precursors participate in mammalian brain development

1997 • 313 citations

Morphine induces apoptosis of human microglia and neurons

2002 • 312 citations

Role of Chemokines in Angiogenesis: CXCL12/SDF‐1 and CXCR4 Interaction, a Key Regulator of Endothelial Cell Responses

2003 • 302 citations

Role of the ?-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system

2003 • 277 citations

B Lymphocyte Chemotaxis Regulated in Association with Microanatomic Localization, Differentiation State, and B Cell Receptor Engagement

1998 • 276 citations

Expression of Functional CXCR4 by Muscle Satellite Cells and Secretion of SDF-1 by Muscle-Derived Fibroblasts is Associated with the Presence of Both Muscle Progenitors in Bone Marrow and Hematopoietic Stem/Progenitor Cells in Muscles

2003 • 272 citations

Multipotent and restricted precursors in the central nervous system

1999 • 269 citations

Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons

2002 • 238 citations

Role of Chemokines in Angiogenesis: CXCL12/SDF-1 and CXCR4 Interaction, a Key Regulator of Endothelial Cell Responses

2003 • 210 citations

Cell Contact Regulates Fate Choice by Cortical Stem Cells

2000 • 205 citations

Human Neural Stem Cells: Isolation, Expansion and Transplantation

1999 • 203 citations

Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer

2002 • 173 citations

Chemokines Promote Quiescence and Survival of Human Neural Progenitor Cells

2004 • 163 citations

Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain.

1995 • 154 citations

Stromal cell‐derived factor 1‐mediated CXCR4 signaling in rat and human cortical neural progenitor cells

2004 • 152 citations

Mitogen and Substrate Differentially Affect the Lineage Restriction of Adult Rat Subventricular Zone Neural Precursor Cell Populations

1999 • 145 citations

Macrophage migration inhibitory factor: Roles in regulating tumor cell migration and expression of angiogenic factors in hepatocellular carcinoma

2003 • 135 citations

Cell that are O4 antigen-positive and O1 antigen-negative differentiate into O1 antigen-positive oligodendrocytes

1982 • 135 citations

Developmental pattern of expression of the alpha chemokine stromal cell‐derived factor 1 in the rat central nervous system

2001 • 132 citations

Immunolocalization of HIV envelope gp120 in HIV encephalitis with dementia

2000 • 113 citations

The CCR3 Receptor Is Involved in Eosinophil Differentiation and Is Up-Regulated by Th2 Cytokines in CD34+ Progenitor Cells

2003 • 107 citations

Human neural stem cells improve cognitive function of aged brain

2001 • 106 citations

Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation

2003 • 100 citations

Neural progenitors and stem cells: mechanisms of progenitor heterogeneity

1998 • 96 citations

Microarray analysis of selected genes in neural stem and progenitor cells

2002 • 94 citations

Embryonic expression of the mRNA for the rat homologue of the fusin/CXCR-4 HIV-1 co-receptor

1997 • 75 citations

Expression of Glial and Vimentin Type Intermediate Filaments in Cultures Derived from Human Glial Material

1981 • 67 citations

Stem cells and the cellular organization of the brain

2000 • 35 citations

Response of Human CD34+Cells to CXC, CC, and CX3C Chemokines: Implications for Cell Migration and Activation

2001 • 31 citations

Differentiation of CD34+ cells from human cord blood and murine bone marrow is suppressed by C6 beta-chemokines.

2003 • 28 citations

Environmental Signals Influence Expression of a Cortical Areal Phenotypein VitroIndependent of Effects on Progenitor Cell Proliferation

1996 • 25 citations

CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors

2001 • 24 citations

Chemokines: New, Key Players in the Pathobiology of Pancreatic Cancer

2002 • 22 citations

Differentiation of CD34+ Cells from Human Cord Blood and Murine Bone Marrow Is Suppressed by C6 β-Chemokines

2003 • 21 citations

SDF-1 enhances the expansion and maintenance of highly purified human hematopoietic progenitors

2003 • 16 citations

Cited By (0)

Loading...