High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells
Data up to Jan 2025
Total Citations Per Year
Abstract
References (60)
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
1998 • 2,496 citations
The Biology of Chemokines and their Receptors
2000 • 2,416 citations
Direct isolation of human central nervous system stem cells
2000 • 1,822 citations
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
1998 • 1,687 citations
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
1992 • 1,514 citations
The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood
1997 • 1,414 citations
Clonal and Population Analyses Demonstrate That an EGF-Responsive Mammalian Embryonic CNS Precursor Is a Stem Cell
1996 • 1,366 citations
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
2002 • 1,335 citations
Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy
2003 • 1,259 citations
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.
1996 • 1,164 citations
The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses
2000 • 1,077 citations
Isolation, Characterization, and use of Stem Cells from the CNS
1995 • 819 citations
Identification of major cell classes in the developing mammalian nervous system
1985 • 803 citations
Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
2003 • 758 citations
bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
1993 • 651 citations
Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain
2003 • 640 citations
NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4
2003 • 624 citations
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
2003 • 595 citations
The expression and posttranslational modification of a neuron‐specific β‐tubulin isotype during chick embryogenesis
1990 • 589 citations
Hematopoietic Stem Cells Are Uniquely Selective in Their Migratory Response to Chemokines
2002 • 518 citations
In Vitro Expansion of a Multipotent Population of Human Neural Progenitor Cells
1999 • 501 citations
Regulation of neurogenesis by growth factors and neurotransmitters
1998 • 483 citations
Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4
1998 • 419 citations
Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor
2002 • 413 citations
Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4
1998 • 411 citations
In vitro -generated neural precursors participate in mammalian brain development
1997 • 313 citations
Morphine induces apoptosis of human microglia and neurons
2002 • 312 citations
Role of Chemokines in Angiogenesis: CXCL12/SDF‐1 and CXCR4 Interaction, a Key Regulator of Endothelial Cell Responses
2003 • 302 citations
Role of the ?-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system
2003 • 277 citations
B Lymphocyte Chemotaxis Regulated in Association with Microanatomic Localization, Differentiation State, and B Cell Receptor Engagement
1998 • 276 citations
Expression of Functional CXCR4 by Muscle Satellite Cells and Secretion of SDF-1 by Muscle-Derived Fibroblasts is Associated with the Presence of Both Muscle Progenitors in Bone Marrow and Hematopoietic Stem/Progenitor Cells in Muscles
2003 • 272 citations
Multipotent and restricted precursors in the central nervous system
1999 • 269 citations
Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons
2002 • 238 citations
Role of Chemokines in Angiogenesis: CXCL12/SDF-1 and CXCR4 Interaction, a Key Regulator of Endothelial Cell Responses
2003 • 210 citations
Cell Contact Regulates Fate Choice by Cortical Stem Cells
2000 • 205 citations
Human Neural Stem Cells: Isolation, Expansion and Transplantation
1999 • 203 citations
Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer
2002 • 173 citations
Chemokines Promote Quiescence and Survival of Human Neural Progenitor Cells
2004 • 163 citations
Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain.
1995 • 154 citations
Stromal cell‐derived factor 1‐mediated CXCR4 signaling in rat and human cortical neural progenitor cells
2004 • 152 citations
Mitogen and Substrate Differentially Affect the Lineage Restriction of Adult Rat Subventricular Zone Neural Precursor Cell Populations
1999 • 145 citations
Macrophage migration inhibitory factor: Roles in regulating tumor cell migration and expression of angiogenic factors in hepatocellular carcinoma
2003 • 135 citations
Cell that are O4 antigen-positive and O1 antigen-negative differentiate into O1 antigen-positive oligodendrocytes
1982 • 135 citations
Developmental pattern of expression of the alpha chemokine stromal cell‐derived factor 1 in the rat central nervous system
2001 • 132 citations
Immunolocalization of HIV envelope gp120 in HIV encephalitis with dementia
2000 • 113 citations
The CCR3 Receptor Is Involved in Eosinophil Differentiation and Is Up-Regulated by Th2 Cytokines in CD34+ Progenitor Cells
2003 • 107 citations
Human neural stem cells improve cognitive function of aged brain
2001 • 106 citations
Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation
2003 • 100 citations
Neural progenitors and stem cells: mechanisms of progenitor heterogeneity
1998 • 96 citations
Microarray analysis of selected genes in neural stem and progenitor cells
2002 • 94 citations
Embryonic expression of the mRNA for the rat homologue of the fusin/CXCR-4 HIV-1 co-receptor
1997 • 75 citations
Expression of Glial and Vimentin Type Intermediate Filaments in Cultures Derived from Human Glial Material
1981 • 67 citations
Stem cells and the cellular organization of the brain
2000 • 35 citations
Response of Human CD34+Cells to CXC, CC, and CX3C Chemokines: Implications for Cell Migration and Activation
2001 • 31 citations
Differentiation of CD34+ cells from human cord blood and murine bone marrow is suppressed by C6 beta-chemokines.
2003 • 28 citations
Environmental Signals Influence Expression of a Cortical Areal Phenotypein VitroIndependent of Effects on Progenitor Cell Proliferation
1996 • 25 citations
CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors
2001 • 24 citations
Chemokines: New, Key Players in the Pathobiology of Pancreatic Cancer
2002 • 22 citations
Differentiation of CD34+ Cells from Human Cord Blood and Murine Bone Marrow Is Suppressed by C6 β-Chemokines
2003 • 21 citations
SDF-1 enhances the expansion and maintenance of highly purified human hematopoietic progenitors
2003 • 16 citations