Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

2003 • 7,170 citations

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1996 • 1,973 citations

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1998 • 1,687 citations

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1996 • 1,678 citations

Chemokines and disease

2001 • 1,371 citations

CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

2001 • 1,024 citations

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

1999 • 999 citations

CCR5⁺and CXCR3⁺T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions

1999 • 839 citations

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1998 • 837 citations

CXC chemokines in angiogenesis

2000 • 811 citations

The α-Chemokine, Stromal Cell-derived Factor-1α, Binds to the Transmembrane G-protein-coupled CXCR-4 Receptor and Activates Multiple Signal Transduction Pathways

1998 • 627 citations

Dancing to the tune of chemokines

2001 • 624 citations

HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication

1997 • 564 citations

Cc Chemokine Receptor 2 Is Critical for Induction of Experimental Autoimmune Encephalomyelitis

2000 • 510 citations

Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants.

1989 • 497 citations

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4

1998 • 419 citations

A Possible Role for CXCR4 and Its Ligand, the CXC Chemokine Stromal Cell-Derived Factor-1, in the Development of Bone Marrow Metastases in Neuroblastoma

2001 • 419 citations

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

2002 • 413 citations

Chemokines and Their Receptors in the Central Nervous System

2001 • 402 citations

Expression of monocyte chemoattractant protein-1 and other β-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions

1998 • 400 citations

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study

1998 • 371 citations

Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma.

2000 • 371 citations

International Union of Pharmacology. XXX. Update on Chemokine Receptor Nomenclature

2002 • 346 citations

Epithelial cancer cell migration: a role for chemokine receptors?

2001 • 342 citations

A central role for astrocytes in the inflammatory response to β-amyloid; chemokines, cytokines and reactive oxygen species are produced

1999 • 313 citations

The CXC Chemokines IP-10 and Mig Are Necessary for IL-12-Mediated Regression of the Mouse RENCA Tumor

1998 • 295 citations

Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C

2000 • 266 citations

Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease

1999 • 263 citations

The CXC Chemokine Stromal Cell-Derived Factor Activates a Gi-Coupled Phosphoinositide 3-Kinase in T Lymphocytes

1999 • 253 citations

The Chemokine Growth-Regulated Oncogene-α Promotes Spinal Cord Oligodendrocyte Precursor Proliferation

1998 • 227 citations

The Chemokine Monocyte Chemotactic Protein 1 Triggers Janus Kinase 2 Activation and Tyrosine Phosphorylation of the CCR2B Receptor

1998 • 224 citations

Signal Transduction by Cxc Chemokine Receptor 4

2000 • 222 citations

Glial and Neuronal Cells Express Functional Chemokine Receptor CXCR4 and Its Natural Ligand Stromal Cell‐Derived Factor 1

1999 • 220 citations

Stromal cell‐derived factor‐1α induces astrocyte proliferation through the activation of extracellular signal‐regulated kinases 1/2 pathway

2001 • 187 citations

Induction of experimental autoimmune encephalomyelitis in C57BL / 6 mice deficient in either the chemokine macrophage inflammatory protein-1α or its CCR5 receptor

2000 • 163 citations

Differential signalling of the chemokine receptor CXCR4 by stromal cell‐derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes

2000 • 159 citations

Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12

1998 • 151 citations

CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells

1998 • 149 citations

CXC chemokines interleukin-8 (IL-8) and growth-related gene product α (GROα) modulate Purkinje neuron activity in mouse cerebellum

1998 • 148 citations

The chemokine interleukin‐8 acutely reduces Ca²⁺ currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs

2001 • 135 citations

Developmental pattern of expression of the alpha chemokine stromal cell‐derived factor 1 in the rat central nervous system

2001 • 132 citations

HIV-1 Tat Causes Apoptotic Death and Calcium Homeostasis Alterations in Rat Neurons

2001 • 125 citations

Expression of ?-chemokines and chemokine receptors in human fetal astrocyte and microglial co-cultures: Potential role of chemokines in the developing CNS

2001 • 120 citations

CXC Chemokine Receptor 4 Expression and Function in Human Astroglioma Cells

2001 • 116 citations

β-Chemokine Receptor CCR5 Signals through SHP1, SHP2, and Syk

2000 • 88 citations

RANTES promotes growth and survival of human first-trimester forebrain astrocytes

2001 • 80 citations

Expression of Chemokine Receptors in the Rat Brain^a

1999 • 69 citations

Identification of fractalkine, a CX3C-type chemokine, as a direct target of p53.

2000 • 59 citations

TGF-?1 prevents gp120-induced impairment of Ca2+ homeostasis and rescues cortical neurons from apoptotic death

1997 • 52 citations

Growth inhibition of human glioma cells modulated by retrovirus gene transfection with antisense IL-8

1995 • 28 citations

Constitutive and inflammatory induction of α and β chemokines in human first trimester forebrain astrocytes and neurons

2002 • 23 citations