bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes

1992 • 1,514 citations

A common progenitor for neurons and glia persists in rat retina late in development

1987 • 1,395 citations

Isolation of a stem cell for neurons and glia from the mammalian neural crest

1992 • 796 citations

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture

1988 • 760 citations

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

1992 • 760 citations

Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics

1983 • 758 citations

Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension.

1986 • 741 citations

Glial Cell Diversification in the Rat Optic Nerve

1989 • 725 citations

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

1990 • 720 citations

Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture.

1986 • 696 citations

Multipotent Precursors Can Give Rise to All Major Cell Types of the Frog Retina

1988 • 663 citations

Lineage-independent determination of cell type in the embryonic mouse retina

1990 • 656 citations

Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.

1990 • 635 citations

Purification of a fibroblast growth factor from bovine pituitary.

1975 • 595 citations

A dual receptor system is required for basic fibroblast growth factor activity

1991 • 589 citations

FGF modulates the PDGF-driven pathway of oligodendrocyte development

1990 • 586 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

Proliferation and differentiation of rat neuroepithelial precursor cells in vivo

1988 • 563 citations

FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.

1991 • 541 citations

Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions

1988 • 529 citations

Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons.

1987 • 495 citations

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

1989 • 492 citations

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

1991 • 462 citations

Division and differentiation of isolated CNS blast cells in microculture

1989 • 404 citations

Developmental expression of two murine fibroblast growth factor receptors, fig and bek

1991 • 397 citations

Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization

1990 • 387 citations

Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation

1993 • 381 citations

Guanylyl cyclase receptors and their endocrine, paracrine, and autocrine ligands

1992 • 346 citations

Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro

1987 • 336 citations

Immortalization of precursor cells from the mammalian CNS

1988 • 328 citations

Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture

1989 • 318 citations

A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve: In vivo evidence for two distinct astrocyte lineages

1985 • 316 citations

The neural crest cell lineage problem: Neuropoiesis?

1989 • 315 citations

Neurons, astrocytes, and oligodendrocytes of the rat cerebral cortex originate from separate progenitor cells: an ultrastructural analysis of clonally related cells

1993 • 311 citations

Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.

1989 • 294 citations

EGF and TGF-α stimulate retinal neuroepithelial cell proliferation in vitro

1991 • 286 citations

Ion channel expression by white matter glia: I. Type 2 astrocytes and oligodendrocytes

1988 • 284 citations

Control of proliferation in the retina: temporal changes in responsiveness to FGF and TGFα

1992 • 276 citations

The generation of neurons and oligodendrocytes from a common precursor cell

1991 • 274 citations

Growth of purified astrocytes in a chemically defined medium.

1981 • 268 citations

Fibroblast growth factor stimulates the proliferation and differentiation of neural precursor cells in vitro

1990 • 257 citations

Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies.

1990 • 241 citations

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

1993 • 240 citations

Two glial cell lineages diverge prenatally in rat optic nerve

1984 • 232 citations

Two forms of the basic fibroblast growth factor receptor-like mRNA are expressed in the developing mouse brain.

1990 • 228 citations

Fibroblast growth factor is a mitogen for oligodendrocytes in vitro

1985 • 227 citations

A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF

1990 • 205 citations

Generation and migration of cells in the developing striatum

1992 • 183 citations

The origins of cellular diversity in the mammalian central nervous system

1989 • 173 citations

Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity

1992 • 148 citations

Basic fibroblast growth factor promotes In vitro survival and cholinergic development of rat septal neurons: Comparison with the effects of nerve growth factor

1989 • 142 citations

Gliogenesis in rat optic nerve: Astrocytes are generated in a single wave before oligodendrocytes

1990 • 133 citations

Effects of acidic and basic fibroblast growth factors on proliferation and maturation of cultured rat oligodendrocytes

1989 • 133 citations

Ion channels in spinal cord astrocytes in vitro. I. Transient expression of high levels of Na+ and K+ channels

1992 • 121 citations

Ion channels in spinal cord astrocytes in vitro. II. Biophysical and pharmacological analysis of two Na+ current types

1992 • 109 citations

Effects of acidic and basic fibroblast growth factors (aFGF and bFGF) on the proliferation and the glutamine synthetase expression of rat astroblasts in culture

1988 • 104 citations

Alternative splicing generates at least five different isoforms of the human basic-FGF receptor.

1991 • 104 citations

Voltage-gated ion channels in schwann cells and glia

1992 • 94 citations

Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures

1987 • 86 citations

Basic fibroblast growth factor (bFGF), a multifunctional growth factor for neuroectodermal cells

1990 • 67 citations

Multiple Neurotrophic Factors from Skeletal Muscle: Demonstration of Effects of Basic Fibroblast Growth Factor and Comparisons with the 22‐Kilodalton Choline Acetyltransferase Development Factor

1989 • 61 citations

Establishment of pure neuronal cultures from fetal rat spinal cord and proliferation of the neuronal precursor cells in the presence of fibroblast growth factor

1991 • 57 citations

Rapid isolation and purification of DNA from agarose gels: the phenol-freeze-fracture method.

1991 • 31 citations

Fibroblast growth factor-induced increased survival of chollnergic mesopontine neurons in culture

1991 • 23 citations

Effects of basic fibroblast growth factor on the development of GABAergic neurons in culture

1991 • 23 citations

Impulses and resting membrane properties of small cultured rat hippocampal neurons.

1992 • 23 citations

Influence of basic fibroblast growth factor on carbonic anhydrase expression by rat glial cells in primary culture

1988 • 17 citations

Putative structure of the FGF6 gene product and role of the signal peptide.

1991 • 16 citations