Transcription Stimulation of the Fas-encoding Gene by Nuclear Factor for Interleukin-6 Expression upon Influenza Virus Infection

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

Cytokine signal transduction

1994 • 1,358 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

1993 • 955 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen.

1992 • 839 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6.

1993 • 587 citations

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes.

1994 • 560 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Purification and characterization of the Fas-ligand that induces apoptosis.

1994 • 521 citations

Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.

1992 • 510 citations

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

1991 • 432 citations

Apoptosis: a mechanism of cell killing by influenza A and B viruses

1994 • 431 citations

Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβ

1992 • 398 citations

DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement

1992 • 392 citations

Apoptosis in AIDS

1993 • 375 citations

The cytopathic effect of hiv is associated with apoptosis

1991 • 358 citations

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1993 • 345 citations

The Interferon-induced Double-Stranded RNA-Activated Protein Kinase Induces Apoptosis

1994 • 322 citations

Induction of programmed cell death (apoptosis) by influenza virus infection in tissue culture cells

1993 • 319 citations

A Nuclear Factor for Interleukin-6 Expression (NF-IL6) and the Glucocorticoid Receptor Synergistically Activate Transcription of the Rat α1-Acid Glycoprotein Gene via Direct Protein-Protein Interaction

1993 • 215 citations

The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.

1993 • 210 citations

Membrane Expression of HIV Envelope Glycoproteins Triggers Apoptosis in CD4 Cells

1993 • 210 citations

Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection

1992 • 208 citations

The Double Stranded RNA-Activated Protein Kinase Induced by Interferon: dsRNA-PK

1989 • 202 citations

Programmed cell death and AIDS: from hypothesis to experiment

1992 • 167 citations

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells.

1990 • 164 citations

Programmed cell death of T lymphocytes during acute viral infection: a mechanism for virus-induced immune deficiency

1993 • 147 citations

Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elements.

1994 • 144 citations

Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication.

1990 • 127 citations

NF-IL6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1.

1993 • 111 citations

The organization and the complete nucleotide sequence of the human NADH-cytochrome b5 reductase gene

1989 • 102 citations

HIV-1 infection of human CD4+ T cells in vitro. Differential induction of apoptosis in these cells.

1994 • 87 citations

The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes

1990 • 84 citations

The basis for the mechanistic bias for deletional over inversional V(D)J recombination.

1992 • 79 citations

New Concepts in AIDS Pathogenesis

1993 • 79 citations

Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA

1985 • 78 citations

Fas antigen mRNA induction in postischemic murine brain

1994 • 76 citations

Specific binding of influenza A virus NS1 protein to the virus minus-sense RNA in vitro

1992 • 58 citations

Apoptosis II: The molecular basis of apoptosis in disease

1994 • 43 citations

Murine retrovirus-induced depletion of T cells is mediated through activation-induced death by apoptosis

1994 • 34 citations

Increased Fas antigen expression in murine retrovirus‐induced immunodeficiency syndrome, MAIDS

1994 • 28 citations

An established CD4+ T lymphoma cell line derived from a patient with so- called Lennert's lymphoma: possible roles of cytokines in histopathogenesis

1988 • 27 citations

Superinfection-induced apoptosis and its correlation with the reduction of viral progeny in cells persistently infected with Hz-1 baculovirus

1993 • 23 citations

Transcription stimulation of the adenovirus type 12 E1a gene in vitro by the 266-amino-acid E1A protein

1994 • 6 citations