Murine retrovirus-induced depletion of T cells is mediated through activation-induced death by apoptosis

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 • 1,194 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1987 • 923 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

The Reservoir for HIV-1 in Human Peripheral Blood Is a T Cell That Maintains Expression of CD4

1989 • 732 citations

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

1992 • 689 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

Death and the cell

1986 • 616 citations

The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells

1990 • 589 citations

Programmed Cell Death in the Immune System

1991 • 575 citations

Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration

1989 • 549 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes

1989 • 513 citations

2,3,7,8-Tetrachlorodibenzo- p -Dioxin Kills Immature Thymocytes by Ca ²⁺ -Mediated Endonuclease Activation

1988 • 460 citations

Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.

1990 • 443 citations

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

1991 • 432 citations

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

1990 • 375 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Mitogens increase phosphorylation of phosphoinositides in thymocytes

1984 • 223 citations

Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection

1992 • 208 citations

Activation-driven T cell death. I. Requirements for de novo transcription and translation and association with genome fragmentation.

1989 • 194 citations

Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2.

1993 • 177 citations

Cytokine modulation of HIV expression

1993 • 147 citations

Interleukin 1 inhibits T cell receptor-mediated apoptosis in immature thymocytes.

1990 • 125 citations

Human papillomavirus 16 E7 protein is associated with the nuclear matrix.

1991 • 100 citations

A Val-25-to-Ile substitution in the envelope precursor polyprotein, gPr80env, is responsible for the temperature sensitivity, inefficient processing of gPr80env, and neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB

1990 • 86 citations

Apoptosis induced by tumor necrosis factor in cells chronically infected with feline immunodeficiency virus

1993 • 74 citations

Defective signal transduction—a common pathway for cellular dysfunction in HIV infection?

1990 • 69 citations

Glucocorticoid-induced cell-size changes and nuclear fragility in rat thymocytes

1981 • 63 citations

Moloney Murine Leukemia Virus Temperature-Sensitive Mutants: A Model for Retrovirus-Induced Neurologic Disorders

1990 • 63 citations

Human immunodeficiency virus type 1 glycoprotein precursor retains a CD4-p56lck complex in the endoplasmic reticulum

1992 • 61 citations

On the Statistical Distribution of Epidermal Papillomata in Mice

1964 • 59 citations

Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virus

1993 • 55 citations

Intracellular distribution of the envelope glycoprotein of human immunodeficiency virus and its role in the production of cytopathic effect in CD4+ and CD4- human cell lines

1990 • 55 citations

ts1, A mutant of moloney murine leukemia virus-TB, causes both immunodeficiency and neurologic disorders in BALB/c Mice

1989 • 51 citations

Lymphocytotoxic strains of feline leukemia virus induce apoptosis in feline T4-thymic lymphoma cells.

1992 • 48 citations

Replication of murine leukemia virus in heterologous cells: Interaction between ecotropic and xenotropic viruses

1981 • 42 citations

Molecular cloning of two paralytogenic, temperature-sensitive mutants, ts1 and ts7, and the parental wild-type Moloney murine leukemia virus

1985 • 41 citations

High susceptibility of FVB/N mice to the paralytic disease induced by ts1, a mutant of Moloney murine leukemia virus TB

1991 • 33 citations

Programmed cell death in heterokaryons. A study of the transfer of apoptosis between nuclei.

1992 • 28 citations

Staphylococcal exotoxin superantigens induce human immunodeficiency virus type 1 expression in naturally infected CD4+ T cells

1992 • 26 citations

Molecular Basis of Neurologic Disorders Induced by a Mutant, ts1, of Moloney Murine Leukemia Virus

1992 • 25 citations

The role of the thymus in the pathogenesis of hind-limb paralysis induced by ts1, a mutant of moloney murine leukemia virus-TB

1989 • 21 citations

ts1, a temperature-sensitive mutant of Moloney murine leukemia virus TB, can infect both CD4+ and CD8+ T cells but requires CD4+ T cells in order to cause paralysis and immunodeficiency

1992 • 20 citations

Temporal lymphoreticular changes caused by ts1, a paralytogenic mutant of Moloney murine leukemia virus TB.

1992 • 20 citations

Alteration from T- to B-cell tropism reduces thymic atrophy and cytocidal effects in thymocytes but not neurovirulence induced by ts1, a mutant of Moloney murine leukemia virus TB.

1991 • 16 citations

Protective role of cytotoxic lymphocytes against murine leukemia virus-induced neurologic disease and immunodeficiency is enhanced by the presence of helper T cells

1992 • 14 citations

Rudimentary Thymus of SCID Mouse Plays an Important Role in the Development of Retrovirus-Induced Neurologic Disorders

1993 • 11 citations

T, not B, lymphocytes are required for immunodeficiency and paralysis induced by ts1, a mutant of moloney murine leukemia virus-TB

1991 • 10 citations