Predictability of FTY720 efficacy in experimental autoimmune encephalomyelitis by in vivo macrophage tracking: Clinical implications for ultrasmall superparamagnetic iron oxide‐enhanced magnetic resonance imaging

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells

2000 • 1,723 citations

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

Measurement of the blood‐brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts

1991 • 1,442 citations

Accumulation of Ultrasmall Superparamagnetic Particles of Iron Oxide in Human Atherosclerotic Plaques Can Be Detected by In Vivo Magnetic Resonance Imaging

2003 • 794 citations

Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging.

1992 • 681 citations

The role of magnetic resonance techniques in understanding and managing multiple sclerosis

1998 • 553 citations

Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology

1997 • 517 citations

Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis

1993 • 378 citations

FTY720 Immunosuppression Impairs Effector T Cell Peripheral Homing Without Affecting Induction, Expansion, and Memory

2000 • 364 citations

α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels

2001 • 330 citations

Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment

2003 • 281 citations

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

2002 • 265 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. II. FTY720 Prolongs Skin Allograft Survival by Decreasing T Cell Infiltration into Grafts But Not Cytokine Production In Vivo

1998 • 263 citations

DURATION AND SELECTIVITY OF BLOOD-BRAIN BARRIER BREAKDOWN IN CHRONIC RELAPSING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS STUDIED BY GADOLINIUM-DTPA AND PROTEIN MARKERS

1990 • 215 citations

Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles

2001 • 214 citations

In vivo macrophage activity imaging in the central nervous system detected by magnetic resonance

1999 • 208 citations

FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation

2000 • 166 citations

MRI‐based monitoring of inflammation and tissue damage in acute and chronic relapsing EAE

2003 • 165 citations

Mechanisms of inflammation in MS tissue: adhesion molecules and chemokines

1999 • 163 citations

Lymph node metastases from head and neck squamous cell carcinoma: MR imaging with ultrasmall superparamagnetic iron oxide particles (Sinerem MR) – results of a phase-III multicenter clinical trial

2001 • 162 citations

ICAM-1 expression in autoimmune encephalitis visualized using magnetic resonance imaging

2000 • 142 citations

Selective MR imaging of labeled human peripheral blood mononuclear cells by liposome mediated incorporation of dextran‐magnetite particles

1993 • 139 citations

Dynamic patterns of USPIO enhancement can be observed in macrophages after ischemic brain damage

2001 • 139 citations

Pathogenesis of multiple sclerosis: an update on immunology

2002 • 135 citations

FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats.

1996 • 127 citations

Characterization of tissue damage in multiple sclerosis by nuclear magnetic resonance

1999 • 109 citations

Multicenter clinical trial of ultrasmall superparamagnetic iron oxide in the evaluation of mediastinal lymph nodes in patients with primary lung carcinoma

1999 • 94 citations

FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression

2001 • 90 citations

MR microscopy of transgenic mice that spontaneously acquire experimental allergic encephalomyelitis

1998 • 89 citations

In‐vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO

2002 • 88 citations

Immunopathogenesis of the multiple sclerosis lesion

2001 • 83 citations

Chronic relapsing experimental allergic encephalomyelitis in the Lewis rat

1985 • 78 citations

FTY720 Pretreatment Reduces Warm Hepatic Ischemia Reperfusion Injury Through Inhibition of T-Lymphocyte Infiltration

2002 • 72 citations

Method for intracellular magnetic labeling of human mononuclear cells using approved iron contrast agents

1999 • 68 citations

Tagging of T cells with superparamagnetic iron oxide: Uptake kinetics and relaxometry

1996 • 54 citations

Blood—brain barrier breakdown in MBP-specific T cell induced experimental allergic encephalomyelitis

1993 • 46 citations

Magnetic resonance imaging of antibody-mediated demyelinating experimental allergic encephalomyelitis

1994 • 20 citations

Correlation between MRI and clinico-pathological manifestations in Lewis rats protected from experimental allergic encephalomyelitis by acylated synthetic peptide of myelin basic protein

1999 • 17 citations